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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 32, 2017 - Issue 1
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Research Paper

Synthesis and biological evaluation of anti-Toxoplasma gondii activity of a novel scaffold of thiazolidinone derivatives

Simone CarradoriDepartment of Pharmacy, “G. D’Annunzio” University of Chieti-Pescara, Chieti, Italy; View further author information
,
Daniela SecciDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome, Italy; Correspondence[email protected]
View further author information
,
Bruna BizzarriDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome, Italy; View further author information
,
Paola ChimentiDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome, Italy; View further author information
,
Celeste De MonteDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome, Italy; View further author information
,
Paolo GuglielmiDepartment of Drug Chemistry and Technologies, Sapienza University of Rome, Rome, Italy; View further author information
,
Cristina CampestreDepartment of Pharmacy, “G. D’Annunzio” University of Chieti-Pescara, Chieti, Italy; View further author information
,
Daniela RivaneraDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy; View further author information
,
Claudia BordónStanley Division of Developmental Neurovirology, Johns Hopkins University School of Medicine, Baltimore, MD, USAView further author information
&
Lorraine Jones-BrandoStanley Division of Developmental Neurovirology, Johns Hopkins University School of Medicine, Baltimore, MD, USAView further author information
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Pages 746-758 | Received 16 Mar 2017, Accepted 04 Apr 2017, Published online: 24 May 2017

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Francesca Arrighi, Arianna Granese, Paola Chimenti & Paolo Guglielmi. (2023) Novel therapeutic opportunities for Toxoplasma gondii, Trichomonas vaginalis, and Giardia intestinalis infections. Expert Opinion on Therapeutic Patents 33:3, pages 211-245.
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Lidia Węglińska, Adrian Bekier, Nazar Trotsko, Barbara Kaproń, Tomasz Plech, Katarzyna Dzitko & Agata Paneth. (2022) Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2621-2634.
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Gasem Mohammad Abu-Taweel, Munjed M. Ibrahim, Sikandar Khan, Hamed M. Al-Saidi, Meshal Alshamrani, Fahad A. Alhumaydhi & Salman S. Alharthi. (2022) Medicinal Importance and Chemosensing Applications of Pyridine Derivatives: A Review. Critical Reviews in Analytical Chemistry 0:0, pages 1-18.
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Guilherme F. S. Fernandes, Juliana R. Lopes, Jean L. Dos Santos & Cauê B. Scarim. (2023) Phthalimide as a versatile pharmacophore scaffold: Unlocking its diverse biological activities. Drug Development Research 84:7, pages 1346-1375.
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Hamida Jellali, Nasser Amri, Yousef E. Mukhrish, Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Eric Deniau, Mathieu Sauthier, Houcine Ghalla & Naceur Hamdi. (2023) Copper-Catalyzed Asymmetric Hydroboration Reaction of Novel Methylene Isoindolinone Compounds through Microwave Irradiation and Their Antileishmanial and Antitoxoplasma Activities. ACS Omega 8:25, pages 23067-23077.
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Helena Tuszewska, Jacek Szczepański, Sławomir Mandziuk & Nazar Trotsko. (2023) Thiazolidin-4-one-based derivatives – Efficient tools for designing antiprotozoal agents. A review of the last decade. Bioorganic Chemistry 133, pages 106398.
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Katarzyna Dzitko, Barbara Kaproń, Agata Paneth, Adrian Bekier, Tomasz Plech, Piotr Paneth & Nazar Trotsko. (2023) TZD-Based Hybrid Molecules Act as Dual Anti-Mycobacterium tuberculosis and Anti-Toxoplasma gondii Agents. International Journal of Molecular Sciences 24:3, pages 2069.
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Gopal MuthuboopathiThirumurthi RajendranSamina ShanawazDhivya MoorthiJanani ThirunavukkarasuNandhini NandhiniVani Saminathan. (2022) Research Critique of Thiazolidine Analogues. Asian Journal of Research in Chemistry, pages 351-357.
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Munira Alrooqi, Sikandar Khan, Fahad A. Alhumaydhi, Saeed A. Asiri, Meshal Alshamrani, Mutaib M. Mashraqi, Ahmad Alzamami, Asma M. Alshahrani & Afaf A. Aldahish. (2022) A Therapeutic Journey of Pyridine-based Heterocyclic Compounds as Potent Anticancer Agents: A Review (From 2017 to 2021). Anti-Cancer Agents in Medicinal Chemistry 22:15, pages 2775-2787.
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Hetal I. Soni, Navin B. Patel, Rahul B. Parmar, Manuel J. Chan-Bacab & Gildardo Rivera. (2022) Microwave Irradiated Synthesis of Pyrimidine Containing, Thiazolidin-4- ones: Antimicrobial, Anti-Tuberculosis, Antimalarial and Anti-Protozoa Evaluation. Letters in Organic Chemistry 19:9, pages 731-738.
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Yaqi Deng, Rou Pi, Li Niu, Yun Zhao, Dan Ni, Longlong Song, Zi Li, Wangyujing Han, Qinghua Wei, Yuqiao Han, Tong Zhu, Zhengli Luo, Donghui Sun, Suzhen Dong & Shunying Liu. (2022) Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo. European Journal of Medicinal Chemistry 228, pages 114010.
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Paolo Guglielmi & Daniela Secci. 2022. Antiprotozoal Drug Development and Delivery. Antiprotozoal Drug Development and Delivery 293 319 .
Emilia Păunescu, Ghalia Boubaker, Oksana Desiatkina, Nicoleta Anghel, Yosra Amdouni, Andrew Hemphill & Julien Furrer. (2021) The quest of the best – A SAR study of trithiolato-bridged dinuclear Ruthenium(II)-Arene compounds presenting antiparasitic properties. European Journal of Medicinal Chemistry 222, pages 113610.
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Diego A. Molina, Gerardo A. Ramos, Alejandro Zamora-Vélez, Gina M. Gallego-López, Cristian Rocha-Roa, Jorge Enrique Gómez-Marin & Edwar Cortes. (2021) In vitro evaluation of new 4-thiazolidinones on invasion and growth of Toxoplasma gondii. International Journal for Parasitology: Drugs and Drug Resistance 16, pages 129-139.
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Konasale M. Prasad. (2021) Infectious agents as risk factors for psychosis – A time to reconsider and reinvigorate investigations. Schizophrenia Research 233, pages 111-113.
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Jacek Szczepański, Helena Tuszewska & Nazar Trotsko. (2020) Synthesis of a New [3-(4-Chlorophenyl)-4-oxo-1,3-thiazolidin-5-ylidene]acetic Acid Derivative. Molbank 2020:3, pages M1150.
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Rahman Abdizadeh, Farzin Hadizadeh & Tooba Abdizadeh. (2020) In silico studies of novel scaffold of thiazolidin-4-one derivatives as anti-Toxoplasma gondii agents by 2D/3D-QSAR, molecular docking, and molecular dynamics simulations. Structural Chemistry 31:3, pages 1149-1182.
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Beatrice S. Ludwig, João D.G. Correia & Fritz E. Kühn. (2019) Ferrocene derivatives as anti-infective agents. Coordination Chemistry Reviews 396, pages 22-48.
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Diego Molina, Rodrigo Cossio-Pérez, Cristian Rocha-Roa, Lina Pedraza, Edwar Cortes, Alejandro Hernández & Jorge E. Gómez-Marín. (2018) Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18. BMC Genomics 19:1.
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Cristian Rocha-Roa, Diego Molina & Néstor Cardona. (2018) A Perspective on Thiazolidinone Scaffold Development as a New Therapeutic Strategy for Toxoplasmosis. Frontiers in Cellular and Infection Microbiology 8.
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Alessio Nocentini, Davide Moi, Gianfranco Balboni, Valentina Onnis & Claudiu T. Supuran. (2018) Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Bioorganic Chemistry 77, pages 293-299.
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Esteban Vargas, Fernando Echeverri, Yulieth Upegui, Sara Robledo & Wiston Quiñones. (2017) Hydrazone Derivatives Enhance Antileishmanial Activity of Thiochroman-4-ones. Molecules 23:1, pages 70.
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