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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 32, 2017 - Issue 1
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Research Paper

Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea

Supattra BoonruangBioengineering Program, Faculty of Engineering, Burapha University, Muang, Chonburi, Thailand; View further author information
,
Khanistha PrakobsriBioengineering Program, Faculty of Engineering, Burapha University, Muang, Chonburi, Thailand; View further author information
,
Phisit PouyfungDepartment of Biochemistry, Faculty of Science, Mahidol University, Ratchathewi, Bangkok, Thailand; View further author information
,
Ekaruth SrisookDepartment of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Burapha University, Muang, Chonburi, Thailand; View further author information
,
Aruna PrasopthumDepartment of Biochemistry, Faculty of Science, Mahidol University, Ratchathewi, Bangkok, Thailand; View further author information
,
Pornpimol RongnoparutDepartment of Biochemistry, Faculty of Science, Mahidol University, Ratchathewi, Bangkok, Thailand; View further author information
&
Songklod SarapusitDepartment of Biochemistry and Center for Innovation in Chemistry, Faculty of Science, Burapha University, Muang, Chonburi, ThailandCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-6850-3198View further author information
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Pages 1136-1142 | Received 18 May 2017, Accepted 01 Aug 2017, Published online: 31 Aug 2017

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Tingting Zhang, Jinqiu Rao, Wei Li, Kai Wang & Feng Qiu. (2020) Mechanism-based inactivation of cytochrome P450 enzymes by natural products based on metabolic activation. Drug Metabolism Reviews 52:4, pages 501-530.
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Supattra Boonruang, Khanistha Prakobsri, Phisit Pouyfung, Aruna Prasopthum, Pornpimol Rongnoparut & Songklod Sarapusit. (2020) Structure–activity relationship and in vitro inhibition of human cytochrome CYP2A6 and CYP2A13 by flavonoids . Xenobiotica 50:6, pages 630-639.
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Ying Zhang, Jingwen Zhang, Yong Yang & Qiang Liu. (2017) Complete chloroplast genome of Pluchea indica (L.) Less. (Asteraceae) and its phylogenetic analysis. Mitochondrial DNA Part B 2:2, pages 918-919.
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Articles from other publishers (9)

Ni Putu Ermi Hikmawanti, Fadlina Chany Saputri, Arry Yanuar, Ibrahim Jantan, Ratih Asmana Ningrum & Abdul Mun'im. (2024) Insights into the anti-infective effects of Pluchea indica (L.) Less and its bioactive metabolites against various bacteria, fungi, viruses, and parasites. Journal of Ethnopharmacology 320, pages 117387.
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Sabrin R. M. Ibrahim, Alaa A. Bagalagel, Reem M. Diri, Ahmad O. Noor, Hussain T. Bakhsh & Gamal A. Mohamed. (2022) Phytoconstituents and Pharmacological Activities of Indian Camphorweed (Pluchea indica): A Multi-Potential Medicinal Plant of Nutritional and Ethnomedicinal Importance. Molecules 27:8, pages 2383.
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Michaela Šadibolová, Risto O. Juvonen, Seppo Auriola & Iva Boušová. (2022) In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity. Archives of Toxicology 96:3, pages 793-808.
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Panata Iawsipo, Rotsukon Poonbud, Natcha Somtragool, Photsathorn Mutapat & Anan Meejom. (2022) Pluchea indica tea-leaf extracts exert anti-cancer activity by inducing ROS-mediated cytotoxicity on breast and cervical cancer cells . British Food Journal.
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Sabrin R. M. Ibrahim, Abdelsattar M. Omar, Alaa A. Bagalagel, Reem M. Diri, Ahmad O. Noor, Diena M. Almasri, Shaimaa G. A. Mohamed & Gamal A. Mohamed. (2022) Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors. Plants 11:4, pages 539.
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Radim Vrzal. (2021) Genetic and Enzymatic Characteristics of CYP2A13 in Relation to Lung Damage. International Journal of Molecular Sciences 22:22, pages 12306.
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Fangzheng Yin, Lijiao Zhao, Lili Zhang, Yuhe Chen, Guohui Sun, Jintao Li, Na Zhang, Yuancong Xu, Paul Kay-Sheung Chan & Rugang Zhong. (2020) Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone. Biomedicines 8:11, pages 472.
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Long Ma, Gang Jin, Yi Yang, Yao Pang, Wenhao Wang, Hongyi Zhang, Jiawei Liu, Peng Wu, Zequan Wang, Kui Wang, Ruitong Chang, Jialong Li & Zijiang Zhu. (2020) Association between CYP2A13 polymorphisms and lung cancer. Medicine 99:50, pages e23289.
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Mirza Bojić, Martin Kondža, Hrvoje Rimac, Goran Benković & Željan Maleš. (2019) The Effect of Flavonoid Aglycones on the CYP1A2, CYP2A6, CYP2C8 and CYP2D6 Enzymes Activity. Molecules 24:17, pages 3174.
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