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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 33, 2018 - Issue 1
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Research Paper

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

Ashok AspatwarFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6938-7835View further author information
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Holger M. BeckerDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany; View further author information
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Nanda Kumar ParvathaneniDepartment of Radiotherapy, The M-Lab Group, GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands; ;Institut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, MontpellierCedex 05, France; View further author information
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Milka HammarenFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; View further author information
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Aleksandra SvorjovaFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; View further author information
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Harlan BarkerFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; View further author information
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Claudiu T. SupuranNEUROFARBA Department, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Firenze, Italy; ORCID Iconhttp://orcid.org/0000-0003-4262-0323View further author information
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Ludwig DuboisDepartment of Radiotherapy, The M-Lab Group, GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands; ORCID Iconhttp://orcid.org/0000-0002-8887-4137View further author information
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Philippe LambinDepartment of Radiotherapy, The M-Lab Group, GROW – School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands; View further author information
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Mataleena ParikkaFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; View further author information
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Seppo ParkkilaFaculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland; ;Fimlab Ltd. and Tampere University Hospital, Tampere, FinlandView further author information
&
Jean-Yves WinumInstitut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM, Université de Montpellier, MontpellierCedex 05, France; ORCID Iconhttp://orcid.org/0000-0003-3197-3414View further author information
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Pages 1064-1073 | Received 30 Apr 2018, Accepted 25 May 2018, Published online: 17 Jun 2018

Citations (14)

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Emilie Anduran, Ludwig J Dubois, Philippe Lambin & Jean-Yves Winum. (2022) Hypoxia-activated prodrug derivatives of anti-cancer drugs: a patent review 2006 – 2021. Expert Opinion on Therapeutic Patents 32:1, pages 1-12.
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Claudiu T Supuran. (2020) Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors. Journal of Experimental Pharmacology 12, pages 603-617.
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Ashok Aspatwar, Emanuela Berrino, Silvia Bua, Fabrizio Carta, Clemente Capasso, Seppo Parkkila & Claudiu T. Supuran. (2020) Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1765-1772.
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Ashok Aspatwar, Nanda Kumar Parvathaneni, Harlan Barker, Emilie Anduran, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Seppo Parkkila & Jean-Yves Winum. (2020) Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 109-117.
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Ashok Aspatwar, Milka Hammaren, Mataleena Parikka, Seppo Parkkila, Fabrizio Carta, Murat Bozdag, Daniela Vullo & Claudiu T. Supuran. (2020) In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 65-71.
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Articles from other publishers (9)

Zhao-Jie Wang, Yi-Chi Chen, Feng-Cai Zou, Yan Qin, Yan-Yan Zhu, Xia Xiao, Tian-Zhen Xie, Ying-Jie He, Yun-li Zhao & Xiao-Dong Luo. (2023) Phytochemical Analysis and Anti- Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo . Journal of Agricultural and Food Chemistry 71:13, pages 5219-5229.
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Ashok Aspatwar, Martti E. E. Tolvanen, Harlan Barker, Leo Syrjänen, Susanna Valanne, Sami Purmonen, Abdul Waheed, William S. Sly & Seppo Parkkila. (2022) Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology. Physiological Reviews 102:3, pages 1327-1383.
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Małgorzata Sztanke, Jolanta Rzymowska & Krzysztof Sztanke. (2022) Anti-Tumor Active Isopropylated Fused Azaisocytosine-Containing Congeners Are Safe for Developing Danio rerio as Well as Red Blood Cells and Activate Apoptotic Caspases in Human Breast Carcinoma Cells. Molecules 27:4, pages 1211.
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Justina Kazokaitė-Adomaitienė, Holger M. Becker, Joana Smirnovienė, Ludwig J. Dubois & Daumantas Matulis. (2021) Experimental Approaches to Identify Selective Picomolar Inhibitors for Carbonic Anhydrase IX. Current Medicinal Chemistry 28:17, pages 3361-3384.
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Hiroko Matsumoto, Hisako Miyagi, Nobuhiro Nakamura, Yasuhiro Shiga, Toshihiro Ohta, Shoko Fujiwara & Mikio Tsuzuki. (2021) Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae. Toxicology Reports 8, pages 1937-1947.
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Kanchan Aggarwal, Timothy P. Kuka, Mandira Banik, Brenda P. Medellin, Chinh Q. Ngo, Da Xie, Yohaan Fernandes, Tyler L. Dangerfield, Elva Ye, Bailey Bouley, Kenneth A. Johnson, Yan Jessie Zhang, Johann K. Eberhart & Emily L. Que. (2020) Visible Light Mediated Bidirectional Control over Carbonic Anhydrase Activity in Cells and in Vivo Using Azobenzenesulfonamides . Journal of the American Chemical Society 142:34, pages 14522-14531.
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Emilie Anduran, Ashok Aspatwar, Nanda-Kumar Parvathaneni, Dennis Suylen, Silvia Bua, Alessio Nocentini, Seppo Parkkila, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin & Jean-Yves Winum. (2020) Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation. Molecules 25:10, pages 2347.
Crossref
Jingyu Zhang, Yanyan Ba, Su Wang, Huaixia Yang, Xuehui Hou & Zhi Xu. (2019) Nitroimidazole-containing compounds and their antibacterial and antitubercular activities. European Journal of Medicinal Chemistry 179, pages 376-388.
Crossref
Justina Kazokaitė, Holger M. Becker, Harlan R. Barker, Ashok Aspatwar, Seppo Parkkila, Ludwig J. Dubois & Daumantas Matulis. 2019. Carbonic Anhydrase as Drug Target. Carbonic Anhydrase as Drug Target 265 287 .

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