Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

Lianbao YeSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;

Tao ZhaoSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;

Wenjun DuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;

Anhu LiEsa Biotech Co., LTD., Guangzhou, China;

Wei GaoSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China;

Jingrong LiEsa Biotech Co., LTD., Guangzhou, China;

Ling WangJoint International Research Laboratory of Synthetic Biology and Medicine, Guangdong Provincial Engineering and Technology Research Center of Biopharmaceuticals, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China

http://orcid.org/0000-0001-5116-7749

Weiqiang ChenSchool of Basic Courses, Guangdong Pharmaceutical University, Guangzhou, China; Correspondence[email protected]

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Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

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Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

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