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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1
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Short Communication

Discovery of 5-methyl-N-(2-arylquinazolin-7-yl)isoxazole-4-carboxamide analogues as highly selective FLT3 inhibitors

Daseul ImCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaView further author information
,
Hyungwoo MoonCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaView further author information
,
Jinwoong KimCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaView further author information
,
Youri OhCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaView further author information
,
Miyoung JangCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaView further author information
&
Jung-Mi HahCollege of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi-do, KoreaCorrespondence[email protected]
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Pages 1110-1115 | Received 26 Dec 2019, Accepted 10 Apr 2020, Published online: 27 Apr 2020

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Daseul Im, Joonhong Jun, Jihyun Baek, Haejin Kim, Dahyun Kang, Hyunah Bae, Hyunwook Cho & Jung-Mi Hah. (2022) Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 472-486.
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Articles from other publishers (2)

Masoumeh Divar, Najmeh Edraki, Tahereh Damghani, Fatemeh Moosavi, Maryam Mohabbati, Alireza Alipour, Somayeh Pirhadi, Luciano Saso, Soghra Khabnadideh & Omidreza Firuzi. (2023) Novel spiroindoline quinazolinedione derivatives as anticancer agents and potential FLT3 kinase inhibitors. Bioorganic & Medicinal Chemistry 90, pages 117367.
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Shih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, Yi-Ying Chen, Tony Eight Lin, Ssu-Ting Lien, Hui-Ju Tseng, Tzu-Ying Sung, Jui-Hua Hsieh, Wei-Jan Huang, Shiow-Lin Pan & Kai-Cheng Hsu. (2022) Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach. Bioorganic Chemistry 121, pages 105675.
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