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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1
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Research Paper

Discovery of secondary sulphonamides as IDO1 inhibitors with potent antitumour effects in vivo

Shushan Gea State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaORCID Iconhttps://orcid.org/0000-0003-2812-1376View further author information
ORCID Icon,
Haiqing Zhongb State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaView further author information
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Xuewei Maa State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaView further author information
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Yingbo Zhenga State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaView further author information
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Yi Zoua State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaView further author information
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Fang Wanga State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaView further author information
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Yan Wangb State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaView further author information
,
Yue Hub State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaView further author information
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Yuezhen Lic Department of Organic Chemistry, School of Science, China Pharmaceutical University, Nanjing, PR ChinaView further author information
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Wen Liub State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaView further author information
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Wenjie Guob State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8506-3905View further author information
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Qiang Xub State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, PR ChinaCorrespondence[email protected]
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Yisheng Laia State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, Nanjing, PR ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8026-7949View further author information
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Pages 1240-1257 | Received 27 Feb 2020, Accepted 30 Apr 2020, Published online: 28 May 2020

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Peng-Fei Wang, Li-Qiang Yang, Zhao-Hang Shi, Xue-Min Li & Han-Yue Qiu. (2022) An updated patent review of IDO1 inhibitors for cancer (2018–2022). Expert Opinion on Therapeutic Patents 32:11, pages 1145-1159.
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Romain Amador, Ali Tahrioui, Magalie Barreau, Olivier Lesouhaitier, Michael Smietana & Guillaume Clavé. (2023) N -Acylsulfonamide: a valuable moiety to design new sulfa drug analogues . RSC Medicinal Chemistry 14:8, pages 1567-1571.
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Yiming Wang, Tianning Huang, Jian Gu & Ling Lu. (2023) Targeting the metabolism of tumor-infiltrating regulatory T cells. Trends in Immunology 44:8, pages 598-612.
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Yuheng Yan, Lan Huang, Yiming Liu, Ming Yi, Qian Chu, Dechao Jiao & Kongming Wu. (2022) Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity. Journal of Hematology & Oncology 15:1.
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