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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 35, 2020 - Issue 1

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Research Paper

Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H₃ receptor antagonists/inverse agonists containing triazole moiety

Mingxia Songa Medical College, Jinggangshan University, Ji’an, ChinaView further author information

Rui Yana Medical College, Jinggangshan University, Ji’an, ChinaView further author information

Yanhui Zhanga Medical College, Jinggangshan University, Ji’an, ChinaView further author information

Dongfu Guoa Medical College, Jinggangshan University, Ji’an, ChinaView further author information

Naiming Zhoub College of Life Sciences, Zhejiang University, Hangzhou, ChinaCorrespondence[email protected]
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XianQing Denga Medical College, Jinggangshan University, Ji’an, ChinaCorrespondence[email protected]
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Pages 1310-1321 | Received 07 Feb 2020, Accepted 19 May 2020, Published online: 12 Jun 2020

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https://doi.org/10.1080/14756366.2020.1774573
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Małgorzata Strzelecka, Benita Wiatrak, Paulina Jawień, Żaneta Czyżnikowska & Piotr Świątek. (2023) New Schiff bases derived from dimethylpyridine-1,2,4-triazole hybrid as cytotoxic agents targeting gastrointestinal cancers: Design, synthesis, biological evaluation and molecular docking studies. Bioorganic Chemistry 139, pages 106758.
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Ying Wang, Zheshan Quan & Dachuan Liu. (2023) An Active Group with Potential Anti-seizure Activity: A Review on 1,2,4- Triazoles. Letters in Drug Design & Discovery 20:8, pages 1005-1019.
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Bhumi M. Shah, Palmi Modi & Priti Trivedi. (2023) Recent Investigation on Synthetic ‘Triazoles’ Scaffold as Potential Pharmacological Agents: A Comprehensive Survey. Chemistry Africa 6:4, pages 1679-1697.
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Yi Hua, Mingxia Song, Qiaoyue Guo, Yiqin Luo, Xianqing Deng & Yushan Huang. (2023) Antiseizure Properties of Histamine H3 Receptor Antagonists Belonging 3,4-Dihydroquinolin-2(1H)-Ones. Molecules 28:8, pages 3408.
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Claudia V Maurer-Morelli, Jaira F de Vasconcellos, Estela M Bruxel, Cristiane S Rocha, Amanda M do Canto, Helder Tedeschi, Clarissa L Yasuda, Fernando Cendes & Iscia Lopes-Cendes. (2022) Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy. Experimental Biology and Medicine 247:24, pages 2233-2250.
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Alan Talevi. (2022) Antiseizure medication discovery: Recent and future paradigm shifts. Epilepsia Open 7:S1.
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Siamak Beheshti & Mohammad Wasil Wesal. (2022) Anticonvulsant activity of the histamine H3 receptor inverse agonist pitolisant in an electrical kindling model of epilepsy. Neuroscience Letters 782, pages 136685.
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Ying Wang & Dachuan Liu. (2021) An Important Potential Anti-Epileptic/Anticonvulsant Active Group: A Review of 1,2,4-Triazole Groups and Their Action. Drug Research 72:03, pages 131-138.
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Lin Yang, Yi Wang & Zhong Chen. (2021) Central histaminergic signalling, neural excitability and epilepsy. British Journal of Pharmacology 179:1, pages 3-22.
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Feng Xiao, Rui Yan, Yanhui Zhang, Shiben Wang, Shilong Chen, Naiming Zhou & Xianqing Deng. (2020) Synthesis and antiseizure effect evaluation of nonimidazole histamine H 3 receptor antagonists containing the oxazole moiety . Archiv der Pharmazie 354:4.
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Pakhuri Mehta, Przemysław Miszta & Sławomir Filipek. (2021) Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery. Molecules 26:6, pages 1778.
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Chensheng Yu, Han Wang, Lijing Min, Liang Han, Jianjun Shi & Xinghai Liu. (2021) Synthesis, Cyrstal Structure and Fungicidal Activity of New Triazole Compounds Containing Trifluoromethylphenyl Moiety. Chinese Journal of Organic Chemistry 41:11, pages 4498.
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Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H₃ receptor antagonists/inverse agonists containing triazole moiety

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Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H3 receptor antagonists/inverse agonists containing triazole moiety

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Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H₃ receptor antagonists/inverse agonists containing triazole moiety