Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 36, 2021 - Issue 1
Submit an article Journal homepage
1,737
Views
10
CrossRef citations to date
0
Altmetric
Research Paper

Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis

Junmin ZhangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaORCID Iconhttps://orcid.org/0000-0001-5036-5559View further author information
ORCID Icon,
Zai-Qin ZhengSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaView further author information
,
Qianhe XuSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaView further author information
,
Ya LiSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaView further author information
,
Kun GaoSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaCorrespondence[email protected]
View further author information
&
Jianguo FangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2884-3363View further author information
ORCID Icon
Pages 790-801 | Received 30 Jan 2021, Accepted 26 Feb 2021, Published online: 18 Mar 2021

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Qianhe Xu & Junmin Zhang. (2022) Novel strategies for targeting the thioredoxin system for cancer therapy. Expert Opinion on Drug Discovery 17:5, pages 437-442.
Read now
Jia Liang, RuoXiao Zhuang, XueYao Sun, Feng Zhang & Bin Zou. (2021) Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs). Bioengineered 12:1, pages 8583-8593.
Read now

Articles from other publishers (8)

Junmin Zhang, Pei Liu, Jianwei Chen, Dahong Yao, Qing Liu, Juanhong Zhang, Hua-Wei Zhang, Elaine Lai-Han Leung, Xiao-Jun Yao & Liang Liu. (2023) Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression. Pharmacological Research 187, pages 106565.
Crossref
Hong Li, Shuai Hu, Xiayao Wang, Xuewen Jian, Xiuyu Pang, Beixing Li, Yang Bai, Bingyu Zhu, Nan Zou, Jin Lin & Wei Mu. (2022) Toxicological differences of trifloxystrobin and kresoxim-methyl on zebrafish in various levels of exposure routes, organs, cells and biochemical indicators. Chemosphere 306, pages 135495.
Crossref
Qianhe Xu, Junmin Zhang, Zhengjia Zhao, Yajun Chu & Jianguo Fang. (2022) Revealing PACMA 31 as a new chemical type TrxR inhibitor to promote cancer cell apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1869:10, pages 119323.
Crossref
Camelia Bhattacharyya, Surupa Chakraborty & Rajib Sengupta. (2022) NO news: S-(de)nitrosylation of cathepsins and their relationship with cancer. Analytical Biochemistry 655, pages 114872.
Crossref
Junmin Zhang, Yaxiong Chen & Jianguo Fang. (2022) Targeting thioredoxin reductase by micheliolide contributes to radiosensitizing and inducing apoptosis of HeLa cells. Free Radical Biology and Medicine 186, pages 99-109.
Crossref
Junmin Zhang, Qianhe Xu & Di Ma. (2022) Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis. Free Radical Biology and Medicine 180, pages 244-252.
Crossref
Dongzhu Duan, Yanru Wang, Xiaojie Jin, Mi Li, Le Wang, Yunyun Yan, Jian Xiao, Peng Song & Xiaoling Wang. (2021) Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells. Free Radical Biology and Medicine 177, pages 15-23.
Crossref
Junmin Zhang, Qianhe Xu, Hong-Ying Yang, Minghao Yang, Jianguo Fang & Kun Gao. (2021) Inhibition of Thioredoxin Reductase by Santamarine Conferring Anticancer Effect in HeLa Cells. Frontiers in Molecular Biosciences 8.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.