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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Brief Reports

Design, synthesis and biological evaluation of a series of dianilinopyrimidines as EGFR inhibitors

Longjia Yana School of Pharmaceutical Sciences, Guizhou University, Guiyang, China;b State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China;c Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, ChinaORCID Iconhttps://orcid.org/0000-0003-3703-6704View further author information
ORCID Icon,
Qin Wanga School of Pharmaceutical Sciences, Guizhou University, Guiyang, China;c Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, ChinaView further author information
,
Li Liua School of Pharmaceutical Sciences, Guizhou University, Guiyang, China;c Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, ChinaView further author information
&
Yi Lea School of Pharmaceutical Sciences, Guizhou University, Guiyang, China;b State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang, China;c Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, ChinaCorrespondence[email protected]
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Pages 832-843 | Received 16 Dec 2021, Accepted 20 Feb 2022, Published online: 09 Mar 2022

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Nian Rao, Yuyu Ding, Lan Yang, Yue Zhou, Yi Le, Longjia Yan & Li Liu. (2023) Synthesis, crystal structure, DFT calculation and biological activity of 3-((4-chloro-6-((4-morpholinophenyl)amino)-1,3,5-triazin-2-yl)amino)-N-methylthiophene-2-carboxamide. Molecular Crystals and Liquid Crystals 757:1, pages 95-106.
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Yaqing Zuo, Rongrong Li, Yan Zhang, Guochen Bao, Yi Le & Longjia Yan. (2022) Design, synthesis and antitumor activity of 5-trifluoromethylpyrimidine derivatives as EGFR inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2742-2754.
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Articles from other publishers (4)

Yan Zhang, Zhiwu Long, Nian Rao, Yi Le, Li Liu & Longjia Yan. (2023) New phenylisoxazole derivatives: Synthesis, spectroscopic, X-ray, IR, DFT calculation and biological activity studies. Journal of Molecular Structure 1285, pages 135557.
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Longjia Yan, Yaqing Zuo, Kehui Chen, Ying Xu & Yi Le. (2023) Synthesis and Biological Evaluation of 5-Methylpyrimidine Derivatives as Dual Inhibitors of EGFR and Src for Cancer Treatment. HETEROCYCLES 106:4, pages 742.
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Dan Li, San Tu, Yi Le, Yue Zhou, Lan Yang, Yuyu Ding, Lei Huang & Li Liu. (2023) Development of carbazole-based fluorescent probe for highly sensitive application in fluoride ion detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 285, pages 121816.
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Yan Zhang, Zhiwu Long, Longjia Yan, Li Liu, Lan Yang & Yi Le. (2022) Discovery of 4-nitro-3-phenylisoxazole derivatives as potent antibacterial agents derived from the studies of [3 + 2] cycloaddition. RSC Advances 12:39, pages 25633-25638.
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