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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity

Amr Sonousia Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, EgyptCorrespondence[email protected]
,
Rasha A. Hassana Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
,
Eman O. Osmana Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
,
Amr M. Abdoub Department of Microbiology and Immunology, National Research Centre, Dokki, Giza, Egypt
&
Soha H. Emama Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
Pages 2644-2659 | Received 27 Jun 2022, Accepted 24 Aug 2022, Published online: 22 Sep 2022

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Mahmoud G. Abo Al-Hamd, Haytham O. Tawfik, Omeima Abdullah, Koki Yamaguchi, Masaharu Sugiura, Ahmed B. M. Mehany, Mervat H. El-Hamamsy & Tarek F. El-Moselhy. (2023) Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R). Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Articles from other publishers (2)

Eman O. Osman, Soha H. Emam, Amr Sonousi, Mai M. Kandil, Amr M. Abdou & Rasha A. Hassan. (2023) Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors. Drug Development Research.
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Safaa E. Seif, Zeinab Mahmoud, Wagnat W. Wardakhan, Amr M. Abdou & Rasha A. Hassan. (2023) Design and synthesis of novel hexahydrobenzo[4,5]thieno[2,3‐ d ]pyrimidine derivatives as potential anticancer agents with antiangiogenic activity via VEGFR‐2 inhibition, and down‐regulation of PI3K/AKT/mTOR signaling pathway . Drug Development Research.
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