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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Paper

Design, synthesis and biological evaluation of 2-((4-sulfamoylphenyl)amino)-pyrrolo[2,3-d]pyrimidine derivatives as CDK inhibitors

Bo YangInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
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Yanni QuanInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
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Wuli ZhaoInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
,
Yingjie JiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
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Xiaotang YangInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
,
Jianrui LiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
,
Yi LiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
,
Xiujun LiuInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaView further author information
,
Ying WangInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaCorrespondence[email protected]
View further author information
&
Yanping LiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5771-0252View further author information
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Article: 2169282 | Received 18 Oct 2022, Accepted 11 Jan 2023, Published online: 19 Jan 2023

Citations (5)

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Samar El-Kalyoubi, Samiha A. El-Sebaey, Ahmed A. El-Sayed, Moustafa S. Abdelhamid, Fatimah Agili & Sherin M. Elfeky. (2023) Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Peng Zhang, Congcong Shi, Tongbao Dong, Juntao Song & Gang Du. The anticancer therapeutic potential of pyrimidine–sulfonamide hybrids. Future Medicinal Chemistry 0:0, pages 1-20.
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Articles from other publishers (3)

Yuming Zhang, Lianhai Shan, Wentao Tang, Yating Ge, ChengXian Li & Jifa Zhang. (2024) Recent Discovery and Development of Inhibitors that Target CDK9 and Their Therapeutic Indications. Journal of Medicinal Chemistry 67:7, pages 5185-5215.
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Meng Zhou, Ying Liu, Shuo Wang, Jiankang Feng, Huiyan Ni, Chichong Lu & Guofan Jin. (2023) A novel strategy to bind pyrimidine sulfonamide derivatives with odd even chains: exploration of their design, synthesis and biological activity evaluation. Molecular Diversity.
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Z.-Y. Tan, J. Deng, Q.-X. Ye, Z.-F. Zhang & T.-Y. Luo. (2023) Current Developments of Pyrrolo[2,3-d]pyrimidines with Anticancer Potential (A Review). Russian Journal of General Chemistry 93:10, pages 2645-2662.
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