Citations (40)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Sijia Li, Weiwei Li, Yinqi Jin, Bin Wu & Yimou Wu. (2023) Advancements in the development of nucleic acid vaccines for syphilis prevention and control. Human Vaccines & Immunotherapeutics 19:2.
Read now
Read now
Stewart Sell. (2019) How vaccines work: immune effector mechanisms and designer vaccines. Expert Review of Vaccines 18:10, pages 993-1015.
Read now
Read now
Kang Zheng, Man Xu, Yongjian Xiao, Haodang Luo, Yafeng Xie, Jian Yu, Manyi Tan, Yumeng Li, Feijun Zhao, Tiebing Zeng & Yimou Wu. (2018) Immunogenicity and protective efficacy against Treponema pallidum in New Zealand rabbits immunized with plasmid DNA encoding flagellin. Emerging Microbes & Infections 7:1, pages 1-10.
Read now
Read now
Articles from other publishers (37)
Tang Jun, Liu Zhimin, Deng Xi, Wu Hua, Shen Huilong, Peng Jiaofeng, Zheng Kang & Qinghua Xie. (2023) Immunisation with the glycolytic enzyme enolase inhibits dissemination of Treponema pallidum in C57BL/6 mice. Microbial Pathogenesis 184, pages 106374.
Crossref
Crossref
Deniz Gökengin, Teymur Noori, Andrea Alemany, Carlo Bienkowski, Geoffroy Liegon, Ahmet Çağkan İnkaya, Jorge Carrillo, Georg Stary, Katja Knapp, Oriol Mitja & Jean-Michel Molina. (2023) Prevention strategies for sexually transmitted infections, HIV, and viral hepatitis in Europe. The Lancet Regional Health - Europe 34, pages 100738.
Crossref
Crossref
Xiaohong Zhang, Junxia Duan, Yali Wang, Bibo Xie, Jie Zhou, Sisi Zhao, Weiguo Yin, Peng Liu & Feijun Zhao. (2023)
Insight into the invasion process and immune-protective evaluation of Tp0971, a membrane lipoprotein from
Treponema pallidum
. Microbiology Spectrum.
Crossref
Crossref
Dan Liu, Rui Chen, Yong-Jing Wang, Wei Li, Li-Li Liu, Li-Rong Lin, Tian-Ci Yang & Man-Li Tong. (2023) Insights into the protective immune response by immunization with full-length recombinant TprK protein: cellular and humoral responses. npj Vaccines 8:1.
Crossref
Crossref
Yuxing He, Dejun Chen, Yue Fu, Xinzhuo Huo, Feijun Zhao, Ling Yao, Xiuping Zhou, Pengfei Qi, Haoquan Yin, Longgu Cao, Hui Ling & Tiebing Zeng. (2023) Immunization with Tp0954, an adhesin of Treponema pallidum, provides protective efficacy in the rabbit model of experimental syphilis. Frontiers in Immunology 14.
Crossref
Crossref
Lei-Wen Peng, Yu-Jie Gao, Ya-li Cui, Huang Xu & Zheng-Xiang Gao. (2023) Missed opportunities for screening congenital syphilis early during pregnancy: A case report and brief literature review. Frontiers in Public Health 10.
Crossref
Crossref
Eisuke Fukama, Tomoaki Nomura, Daisuke Hatanaka, Michiko Kusakari, Hidehiro Takahashi, Toshihiko Nakamura & Naoto Takahashi. (2023) Cytokine profiles in an extremely preterm infant with congenital syphilis. FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 69:3, pages 185-189.
Crossref
Crossref
Sheila A. Lukehart, Barbara Molini, Alloysius Gomez, Charmie Godornes, Rebecca Hof, Mark C. Fernandez, Ragan A. Pitner, Sean A. Gray, Darrick Carter, Lorenzo Giacani & Caroline E. Cameron. (2022) Immunization with a tri-antigen syphilis vaccine significantly attenuates chancre development, reduces bacterial load, and inhibits dissemination of Treponema pallidum. Vaccine 40:52, pages 7676-7692.
Crossref
Crossref
Jinlin Chen, Jielite Huang, Zhuoran Liu & Yafeng Xie. (2022)
Treponema pallidum
outer membrane proteins: current status and prospects
. Pathogens and Disease 80:1.
Crossref
Crossref
Dejun Chen, Siqian Wang, Yuxing He, Yue Fu, Feijun Zhao, Xiuping Zhou, Haoquan Yin, Jia Wan, Yunting Huang, Yimou Wu, Longgu Cao & Tiebing Zeng. (2022)
Assessment of recombinant antigens Tp0100 and Tp1016 of
Treponema pallidum
for serological diagnosis of syphilis
. Journal of Clinical Laboratory Analysis 36:9.
Crossref
Crossref
Kristina N. Delgado, Jairo M. Montezuma-Rusca, Isabel C. Orbe, Melissa J. Caimano, Carson J. La Vake, Amit Luthra, Christopher M. Hennelly, Fredrick N. Nindo, Jacob W. Meyer, Letitia D. Jones, Jonathan B. Parr, Juan C. Salazar, M. Anthony Moody, Justin D. Radolf & Kelly L. Hawley. (2022)
Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG
+
-Specific B-Cells in the Rabbit Model of Experimental Syphilis
. mBio 13:4.
Crossref
Crossref
Qianqi Chen & Yiyao Yang. (2022) A Review on the Diagnosis and Treatment of Syphilis. Highlights in Science, Engineering and Technology 8, pages 515-522.
Crossref
Crossref
Lucas Gabriel Rodrigues Gomes, Thaís Cristina Vilela Rodrigues, Arun Kumar Jaiswal, Roselane Gonçalves Santos, Rodrigo Bentes Kato, Debmalya Barh, Khalid J. Alzahrani, Hamsa Jameel Banjer, Siomar de Castro Soares, Vasco Azevedo & Sandeep Tiwari. (2022) In Silico Designed Multi-Epitope Immunogen “Tpme-VAC/LGCM-2022” May Induce Both Cellular and Humoral Immunity against Treponema pallidum Infection. Vaccines 10:7, pages 1019.
Crossref
Crossref
A.S. Vickram, Kuldeep Dhama, S. Thanigaivel, Sandip Chakraborty, K. Anbarasu, Nibedita Dey & Rohini Karunakaran. (2022) Strategies for successful designing of immunocontraceptive vaccines and recent updates in vaccine development against sexually transmitted infections - A review. Saudi Journal of Biological Sciences 29:4, pages 2033-2046.
Crossref
Crossref
Barbara Molini, Mark C. Fernandez, Charmie Godornes, Anastassia Vorobieva, Sheila A. Lukehart & Lorenzo Giacani. (2022) B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses. Frontiers in Immunology 13.
Crossref
Crossref
A.V. Kolerova, N.V. Deeva, M.S. Gileva, I.S. Karabanov, V.V. Popov, A.Yu. Tropynina, M.A. Shaidurova & I.G. Sergeeva. (2022) On vaccination against sexually transmitted infections. Klinicheskaya dermatologiya i venerologiya 21:4, pages 424.
Crossref
Crossref
Man Xu, Yafeng Xie, Kang Zheng, Haodang Luo, Manyi Tan, Feijun Zhao, Tiebing Zeng & Yimou Wu. (2021) Two Potential Syphilis Vaccine Candidates Inhibit Dissemination of Treponema pallidum. Frontiers in Immunology 12.
Crossref
Crossref
Abisola Abisoye-Ogunniyan, Isabella M. Carrano, Dina R. Weilhammer, Sean F. Gilmore, Nicholas O. Fischer, Sukumar Pal, Luis M. de la Maza, Matthew A. Coleman & Amy Rasley. (2021) A Survey of Preclinical Studies Evaluating Nanoparticle-Based Vaccines Against Non-Viral Sexually Transmitted Infections. Frontiers in Pharmacology 12.
Crossref
Crossref
Melody Ren, Thomas Dashwood & Sharon Walmsley. (2021) The Intersection of HIV and Syphilis: Update on the Key Considerations in Testing and Management. Current HIV/AIDS Reports 18:4, pages 280-288.
Crossref
Crossref
Kelly L. Hawley, Jairo M. Montezuma-Rusca, Kristina N. Delgado, Navreeta Singh, Vladimir N. Uversky, Melissa J. Caimano, Justin D. Radolf & Amit Luthra. (2021) Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine. Journal of Bacteriology 203:15.
Crossref
Crossref
Ethan Osias, Phoebe Hung, Lorenzo Giacani, Chrysovalantis Stafylis, Kelika A. Konda, Silver K. Vargas, E. Michael Reyes-Díaz, W. Scott Comulada, David A. Haake, Austin M. Haynes, Carlos F. Caceres & Jeffrey D. Klausner. (2020) Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol. BMC Infectious Diseases 20:1.
Crossref
Crossref
Kun Gao, Dong-Mei Xu, Xiao-Rong Lin, Xiao-Zhen Zhu, Hui-Lin Zhang & Man-Li Tong. (2020) Immunization with nontreponemal antigen alters the course of experimental syphilis in the rabbit model. International Immunopharmacology 89, pages 107100.
Crossref
Crossref
Amit Luthra, Jairo M. Montezuma-Rusca, Carson J. La Vake, Morgan LeDoyt, Kristina N. Delgado, Timothy C. Davenport, Mary Fiel-Gan, Melissa J. Caimano, Justin D. Radolf & Kelly L. Hawley. (2020) Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis. PLOS Pathogens 16:9, pages e1008871.
Crossref
Crossref
Edwin David G. McIntosh. (2020) Development of vaccines against the sexually transmitted infections gonorrhoea, syphilis, Chlamydia, herpes simplex virus, human immunodeficiency virus and Zika virus. Therapeutic Advances in Vaccines and Immunotherapy 8, pages 251513552092388.
Crossref
Crossref
Jan A Roth, Fabian C Franzeck, Suraj Balakrishna, Stephan Lautenschlager, Maria Christine Thurnheer, Laurence Toutous Trellu, Matthias Cavassini, Pietro Vernazza, Enos Bernasconi, Dominique Braun, Roger D Kouyos, Manuel Battegay, A Anagnostopoulos, M Battegay, E Bernasconi, J Böni, D L Braun, H C Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, C A Fux, H F Günthard, D Haerry, B Hasse, H H Hirsch, M Hoffmann, I Hösli, M Huber, C R Kahlert, L Kaiser, O Keiser, T Klimkait, R D Kouyos, H Kovari, B Ledergerber, G Martinetti, B Martinez de Tejada, C Marzolini, K J Metzner, N Müller, D Nicca, P Paioni, G Pantaleo, M Perreau, A Rauch, C Rudin, A U Scherrer, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, P Vernazza, G Wandeler, R Weber & S Yerly. (2020) Repeated Syphilis Episodes in HIV-Infected Men Who Have Sex With Men: A Multicenter Prospective Cohort Study on Risk Factors and the Potential Role of Syphilis Immunity. Open Forum Infectious Diseases 7:1.
Crossref
Crossref
Valentina Marchese, Sarah Dal Zoppo, Virginia Quaresima, Benedetta Rossi & Alberto Matteelli. 2020. Sexually Transmitted Infections. Sexually Transmitted Infections
87
104
.
Nikhat Parveen, Mark C. Fernandez, Austin M. Haynes, Rui-Li Zhang, B. Charmie Godornes, Arturo Centurion-Lara & Lorenzo Giacani. (2019) Non-pathogenic Borrelia burgdorferi expressing Treponema pallidum TprK and Tp0435 antigens as a novel approach to evaluate syphilis vaccine candidates. Vaccine 37:13, pages 1807-1818.
Crossref
Crossref
E. David G. McIntosh. (2019) Development of vaccines against gonorrhoea, syphilis, chlamydia, herpes simplex virus, human immunodeficiency virus and Zika virus. Clinical Microbiology and Antimicrobial Chemotherapy 21:4, pages 253-260.
Crossref
Crossref
Rebecca Schmidt, Paul James Carson & Rick J Jansen. (2019) Resurgence of Syphilis in the United States: An Assessment of Contributing Factors. Infectious Diseases: Research and Treatment 12, pages 117863371988328.
Crossref
Crossref
Lenka Mikalová & David Šmajs. 2018. Diagnostics to Pathogenomics of Sexually Transmitted Infections. Diagnostics to Pathogenomics of Sexually Transmitted Infections
211
232
.
Caroline E. Cameron. (2018) Syphilis Vaccine Development: Requirements, Challenges, and Opportunities. Sexually Transmitted Diseases 45:9S, pages S17-S19.
Crossref
Crossref
Sanjiv Kumar, Melissa J. Caimano, Arvind Anand, Abhishek Dey, Kelly L. Hawley, Morgan E. LeDoyt, Carson J. La Vake, Adriana R. Cruz, Lady G. Ramirez, Lenka Paštěková, Irina Bezsonova, David Šmajs, Juan C. Salazar & Justin D. Radolf. (2018)
Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of
Treponema pallidum
subsp.
pallidum
, the Syphilis Spirochete
. mBio 9:3.
Crossref
Crossref
Noah Kojima & Jeffrey D Klausner. (2018) An Update on the Global Epidemiology of Syphilis. Current Epidemiology Reports 5:1, pages 24-38.
Crossref
Crossref
Chelsea L. Shannon & Jeffrey D. Klausner. (2018) The growing epidemic of sexually transmitted infections in adolescents. Current Opinion in Pediatrics 30:1, pages 137-143.
Crossref
Crossref
Wei-Chien Andrew Kao, Helena Pětrošová, Rhodaba Ebady, Karen V. Lithgow, Pablo Rojas, Yang Zhang, Yae-Eun Kim, Yae-Ram Kim, Tanya Odisho, Nupur Gupta, Annette Moter, Caroline E. Cameron & Tara J. Moriarty. (2017) Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete. Scientific Reports 7:1.
Crossref
Crossref
Irwin W. Sherman. 2017. The Power of Plagues. The Power of Plagues
466
484
.
Karen V. Lithgow, Rebecca Hof, Charmaine Wetherell, Drew Phillips, Simon Houston & Caroline E. Cameron. (2017) A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum. Nature Communications 8:1.
Crossref
Crossref