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Original Article

WISP1 is a novel adipokine linked to metabolic parameters in gestational diabetes mellitus

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Pages 942-946 | Received 11 Jan 2016, Accepted 17 May 2016, Published online: 08 Jun 2016

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Adem Yavuz, Mustafa Ata Aydin, Kader Ugur, Suna Aydin, Arzu Senol, Yakup Baykus, Rulin Deniz, İbrahim Sahin, Mehmet Hanifi Yalcin, Berrin Tarakci Gencer, Yaprak Kandemir Deniz, Sefer Ustebay, Zuhal Karaca Karagoz, Elif Emre & Suleyman Aydin. (2023) Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes. Biotechnic & Histochemistry 98:4, pages 243-254.
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Pierre-Olivier Gaudreau, Sylvie Clairefond, Caleb A. Class, Pierre-Luc Boulay, Pavel Chrobak, Bertrand Allard, Feryel Azzi, Sandra Pommey, Kim-Anh Do, Fred Saad, Dominique Trudel, Marian Young & John Stagg. (2019) WISP1 is associated to advanced disease, EMT and an inflamed tumor microenvironment in multiple solid tumors. OncoImmunology 8:5.
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Gulcin Sahin Ersoy, Tugba Altun Ensari, Dogan Vatansever, Volkan Emirdar & Ozge Cevik. (2017) Novel adipokines WISP1 and betatrophin in PCOS: relationship to AMH levels, atherogenic and metabolic profile. Gynecological Endocrinology 33:2, pages 119-123.
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Articles from other publishers (24)

Kenneth Maiese. (2023) Cornerstone Cellular Pathways for Metabolic Disorders and Diabetes Mellitus: Non-Coding RNAs, Wnt Signaling, and AMPK. Cells 12:22, pages 2595.
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Kenneth Maiese. (2023) The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk. Frontiers in Immunology 14.
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Herman Yeger. (2023) CCN proteins: opportunities for clinical studies—a personal perspective. Journal of Cell Communication and Signaling 17:2, pages 333-352.
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Faustino R. Pérez‐López, Junhua Yuan, Manuel Sánchez‐Prieto, María T. López‐Baena, Gonzalo R. Pérez‐Roncero & Seshadri Reddy Varikasuvu. (2023) Maternal and cord blood betatrophin (angiopoietin‐like protein 8) in pregnant women with gestational diabetes and normoglycemic controls: A systematic review, meta‐analysis, and meta‐regression. Diabetes/Metabolism Research and Reviews.
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Kenneth Maiese. (2022) Wnt Signaling and WISP1 (CCN4): Critical Components in Neurovascular Disease, Blood Brain Barrier Regulation, and Cerebral Hemorrhage. Current Neurovascular Research 19:4, pages 379-382.
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Rui Meng, Qianqian Gao, Ranran Liang, Lina Guan, Shanhe Liu, Qinghua Zhu, Dongmei Su, Yixin Xia & Xu Ma. (2022) Changes in gene expression in rat placenta at gestational day 16.5 in response to hyperglycemia. General and Comparative Endocrinology 320, pages 113999.
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Yangyang Cheng, Xiaohui Du, Bilin Zhang & Junxia Zhang. (2021) Increased Serum WISP1 Levels are Associated with Lower Extremity Atherosclerotic Disease in Patients with Type 2 Diabetes Mellitus. Experimental and Clinical Endocrinology & Diabetes 130:04, pages 248-253.
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Li-chao Liu, Shi-ting Xu & Ling Li. (2021) WISP1 is increased in the maternal serum, adipose tissue, and placenta of women with gestational diabetes mellitus. International Journal of Diabetes in Developing Countries 42:2, pages 269-275.
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Olga Pivovarova-Ramich, Jennifer Loske, Silke Hornemann, Mariya Markova, Nicole Seebeck, Anke Rosenthal, Frederick Klauschen, José Castro, René Buschow, Tilman Grune, Volker Lange, Natalia Rudovich & D. Ouwens. (2021) Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity. Cells 10:5, pages 1048.
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Delia Bogdanet, Catriona Reddin, Dearbhla Murphy, Helen C. Doheny, Jose A. Halperin, Fidelma Dunne & Paula M. O’Shea. (2021) Emerging Protein Biomarkers for the Diagnosis or Prediction of Gestational Diabetes—A Scoping Review. Journal of Clinical Medicine 10:7, pages 1533.
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Małgorzata Mirr & Maciej Owecki. (2021) An Update to the WISP-1/CCN4 Role in Obesity, Insulin Resistance and Diabetes. Medicina 57:2, pages 100.
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Fuyan Yang, Wenfa Yang, Guohua Wang, Yaqiong Liu & Jun Jin. (2021) Association of betatrophin amounts with 25-(OH)D levels in patients with gestational diabetes mellitus. Medicine 100:16, pages e25646.
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Lucia Recinella, Giustino Orlando, Claudio Ferrante, Annalisa Chiavaroli, Luigi Brunetti & Sheila Leone. (2020) Adipokines: New Potential Therapeutic Target for Obesity and Metabolic, Rheumatic, and Cardiovascular Diseases. Frontiers in Physiology 11.
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David Karasek, Ondrej Krystynik, Dominika Goldmannova, Lubica Cibickova & Jan Schovanek. (2020) Circulating levels of selected adipokines in women with gestational diabetes and type 2 diabetes. Journal of Applied Biomedicine 18:2-3, pages 54-60.
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Lei Liu, Jiajin Hu, Liu Yang, Ningning Wang, Yang Liu, Xiaotong Wei, Ming Gao, Yinuo Wang, Yanan Ma & Deliang Wen. (2020) Association of WISP1/CCN4 with Risk of Overweight and Gestational Diabetes Mellitus in Chinese Pregnant Women. Disease Markers 2020, pages 1-10.
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Vadim V. Klimontov, Dinara M. Bulumbaeva, Olga N. Fazullina, Alexander P. Lykov, Natalia P. Bgatova, Nikolay B. Orlov, Vladimir I. Konenkov, Andreas F.H. Pfeiffer, Olga Pivovarova-Ramich & Natalia Rudovich. (2019) Circulating Wnt1-inducible signaling pathway protein-1 (WISP-1/CCN4) is a novel biomarker of adiposity in subjects with type 2 diabetes. Journal of Cell Communication and Signaling 14:1, pages 101-109.
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Lei Gu, Na Chen, Zhenhua Li, Fenglei Zhang & Xiaotian Wang. (2019) Relationship of serum Wnt1-inducible signaling pathway protein 1 levels with coronary artery disease and its severity. Coronary Artery Disease 30:7, pages 542-546.
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I. Barchetta, F. A. Cimini, G. Ciccarelli, M. G. Baroni & M. G. Cavallo. (2019) Sick fat: the good and the bad of old and new circulating markers of adipose tissue inflammation. Journal of Endocrinological Investigation 42:11, pages 1257-1272.
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Habib Yaribeygi, Stephen L. Atkin & Amirhossein Sahebkar. (2019) Wingless‐type inducible signaling pathway protein‐1 (WISP1) adipokine and glucose homeostasis. Journal of Cellular Physiology 234:10, pages 16966-16970.
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An-ru Wang, Xue-qin Yan, Cai Zhang, Cai-qi Du, Wen-jun Long, Di Zhan, Jie Ren & Xiao-ping Luo. (2018) Characterization of Wnt1-inducible Signaling Pathway Protein-1 in Obese Children and Adolescents. Current Medical Science 38:5, pages 868-874.
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Tae Woo Jung, Changmuk Kang, Jiwon Goh, Soo In Chae, Hyoung‐Chun Kim, Tae Jin Lee, A.M. Abd El‐Aty & Ji Hoon Jeong. (2018) WISP1 promotes non‐alcoholic fatty liver disease and skeletal muscle insulin resistance via TLR4/JNK signaling. Journal of Cellular Physiology 233:8, pages 6077-6087.
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Burcu Timur, Serap Fırtına Tuncer, Serkan Bodur, Hakan Timur, Aytekin Tokmak, Funda Gucel & Metin Altay. (2018) Serum betatrophin/angiopoietin-like protein 8 (ANGPTL8) levels in pregnancies affected by hyperemesis gravidarum. European Journal of Obstetrics & Gynecology and Reproductive Biology 225, pages 221-227.
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Ilaria Barchetta, Flavia Agata Cimini, Danila Capoccia, Riccardo De Gioannis, Alessandra Porzia, Fabrizio Mainiero, Michele Di Martino, Laura Bertoccini, Marzia De Bernardinis, Frida Leonetti, Marco Giorgio Baroni, Andrea Lenzi & Maria Gisella Cavallo. (2017) WISP1 Is a Marker of Systemic and Adipose Tissue Inflammation in Dysmetabolic Subjects With or Without Type 2 Diabetes. Journal of the Endocrine Society 1:6, pages 660-670.
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Fei-Juan Kong, Lei-Lei Ma, Ge Li, Yi-Xin Chen & Jia-Qiang Zhou. (2017) Circulating Betatrophin Levels and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis. PLOS ONE 12:1, pages e0169941.
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