Advanced search
Publication Cover
Expert Review of Cardiovascular Therapy Volume 14, 2016 - Issue 9
Submit an article Journal homepage
666
Views
26
CrossRef citations to date
0
Altmetric
Review

Therapeutic targeting of autophagy in myocardial infarction and heart failure

Jaime A. RiquelmeAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, ChileView further author information
,
Myra N. ChavezAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, Chile;FONDAP Center for Genome Regulation, Facultad de Ciencias, Universidad de Chile, Santiago, ChileView further author information
,
David Mondaca-RuffAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, ChileView further author information
,
Mario BustamanteAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, Chile;Advanced Center for Chronic Disease (ACCDiS), Division Enfermedades Cardiovasculares, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, ChileView further author information
,
Jose Miguel VicencioAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, Chile;Cancer Institute, University College London, London, UKView further author information
,
Andrew F. G. QuestAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, ChileView further author information
&
Sergio LavanderoAdvanced Center for Chronic Disease (ACCDiS) & Center for Molecular Studies of the Cell (CEMC), Facultad de Ciencias Químicas y Farmacéuticas & Facultad de Medicina, Universidad de Chile, Santiago, Chile;Department of Internal Medicine, Cardiology Division, University of Texas Southwestern Medical Center, Dallas, TX, USACorrespondence[email protected]
View further author information
 show all
Pages 1007-1019 | Received 01 Apr 2016, Accepted 14 Jun 2016, Published online: 28 Jun 2016

Citations (26)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Shiyong Wu, Hairong Zhang, Ningheng Chen, Chuang Zhang & Xueli Guo. (2021) Metformin protects cardiomyocytes against oxygen-glucose deprivation injury by promoting autophagic flux through AMPK pathway. Journal of Drug Targeting 29:5, pages 551-561.
Read now

Articles from other publishers (25)

Mohammad Hosein Farzaei, Fatemeh Ramezani-Aliakbari, Maryam Ramezani-Aliakbari, Mohammad Zarei, Alireza Komaki, Siamak Shahidi, Abdolrahman Sarihi & Iraj Salehi. (2023) Regulatory effects of trimetazidine in cardiac ischemia/reperfusion injury. Naunyn-Schmiedeberg's Archives of Pharmacology 396:8, pages 1633-1646.
Crossref
Karina-Alexandra Cojocaru, Ionut Luchian, Ancuta Goriuc, Lucian-Mihai Antoci, Cristian-Gabriel Ciobanu, Roxana Popescu, Cristiana-Elena Vlad, Mihaela Blaj & Liliana Georgeta Foia. (2023) Mitochondrial Dysfunction, Oxidative Stress, and Therapeutic Strategies in Diabetes, Obesity, and Cardiovascular Disease. Antioxidants 12:3, pages 658.
Crossref
Nan Wang, Limeiting Wang, Changyan Li, Peng Rao, Xun Wang, Yazhou Xu, Lin Yang, Lin Sun & Di Lu. (2022) RBM3 interacts with Raptor to regulate autophagy and protect cardiomyocytes from ischemia–reperfusion-induced injury. Journal of Physiology and Biochemistry 79:1, pages 47-57.
Crossref
Lijuan Jiao, Yuzhe Liu, Xi-Yong Yu, Xiangbin Pan, Yu Zhang, Junchu Tu, Yao-Hua Song & Yangxin Li. (2023) Ribosome biogenesis in disease: new players and therapeutic targets. Signal Transduction and Targeted Therapy 8:1.
Crossref
Haihua Zhang, Wuying Lang, Xin Liu, Jiangsong Bai, Qinghui Jia & Qiumei Shi. (2022) Procyanidin A1 alleviates DSS-induced ulcerative colitis via regulating AMPK/mTOR/p70S6K-mediated autophagy. Journal of Physiology and Biochemistry 78:1, pages 213-227.
Crossref
Yue Wang & Yusi Shen. (2022) Exosomal miR-455-3p from BMMSCs prevents cardiac ischemia-reperfusion injury. Human & Experimental Toxicology 41, pages 096032712211025.
Crossref
Zeng-Jin Wen, Hui Xin, Yong-Chen Wang, Hao-Wen Liu, Yan-Yan Gao & Yin-Feng Zhang. (2021) Emerging roles of circRNAs in the pathological process of myocardial infarction. Molecular Therapy - Nucleic Acids 26, pages 828-848.
Crossref
Mehmet Gunata & Hakan Parlakpinar. (2020) A review of myocardial ischaemia/reperfusion injury: Pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment. Cell Biochemistry and Function 39:2, pages 190-217.
Crossref
Ivonne Olmedo, Gonzalo Pino, Jaime A. Riquelme, Pablo Aranguiz, Magda C. Díaz, Camila López-Crisosto, Sergio Lavandero, Paulina Donoso, Zully Pedrozo & Gina Sánchez. (2020) Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866:5, pages 165659.
Crossref
Myra N. Chávez, Rodrigo A. Morales, Camila López-Crisosto, Juan Carlos Roa, Miguel L. Allende & Sergio Lavandero. (2020) Autophagy Activation in Zebrafish Heart Regeneration. Scientific Reports 10:1.
Crossref
Xin-Yu Zhang, Lin WangWen-Jiang Yan, Xiao-Ting Lu, Xin-Yun Li & Yuan-Yuan Sun. (2020) Period 2 -Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction . Human Gene Therapy 31:1-2, pages 119-128.
Crossref
Zhi Zuo, Peng-fei Zuo, Zu-long Sheng, Xin Wang, Jian-dong Ding & Gen-shan Ma. (2019) Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy. Life Sciences 239, pages 117016.
Crossref
Thomas Seidel, Dominik J. Fiegle, Tim J. Baur, Anne Ritzer, Sandra Nay, Christian Heim, Michael Weyand, Hendrik Milting, Robert H. Oakley, John A. Cidlowski & Tilmann Volk. (2019) Glucocorticoids preserve the t-tubular system in ventricular cardiomyocytes by upregulation of autophagic flux. Basic Research in Cardiology 114:6.
Crossref
Bo-Zong Shao, Shu-Ling Wang, Jun Fang, Zhao-Shen Li, Yu Bai & Kai Wu. (2019) Alpha7 Nicotinic Acetylcholine Receptor Alleviates Inflammatory Bowel Disease Through Induction of AMPK-mTOR-p70S6K-Mediated Autophagy. Inflammation 42:5, pages 1666-1679.
Crossref
Mehrdad Aghaei, Morteza Motallebnezhad, Sajjad Ghorghanlu, Ali Jabbari, Ayesheh Enayati, Maryam Rajaei, Mona Pourabouk, Alireza Moradi, Ali Mohammad Alizadeh & Vahid Khori. (2019) Targeting autophagy in cardiac ischemia/reperfusion injury: A novel therapeutic strategy. Journal of Cellular Physiology 234:10, pages 16768-16778.
Crossref
Liyuan Zou, Xiaokun Ma, Shuo Lin, Bingyuan Wu, Yang Chen & Chaoquan Peng. (2019) Bone marrow mesenchymal stem cell‑derived exosomes protect against myocardial infarction by promoting autophagy. Experimental and Therapeutic Medicine.
Crossref
Xiaoyan Guo, Xiaoguang Wu, Yan Han, Erhu Tian & Jiangtao Cheng. (2018) LncRNA MALAT1 protects cardiomyocytes from isoproterenol‐induced apoptosis through sponging miR‐558 to enhance ULK1‐mediated protective autophagy. Journal of Cellular Physiology 234:7, pages 10842-10854.
Crossref
Jin Li, Deli Zhang, Marit Wiersma & Bianca J.J.M. Brundel. (2018) Role of Autophagy in Proteostasis: Friend and Foe in Cardiac Diseases. Cells 7:12, pages 279.
Crossref
Yanhui Li, Yan Wang, Man Zou, Cong Chen, Yili Chen, Ruicong Xue, Yugang Dong & Chen Liu. (2018) AMPK blunts chronic heart failure by inhibiting autophagy. Bioscience Reports 38:4.
Crossref
Ya-dan Bai, Yu-rong Yang, Xue-pan Mu, Ge Lin, You-ping Wang, Sheng Jin, Ying Chen, Ming-jie Wang & Yi-chun Zhu. (2018) Hydrogen Sulfide Alleviates Acute Myocardial Ischemia Injury by Modulating Autophagy and Inflammation Response under Oxidative Stress. Oxidative Medicine and Cellular Longevity 2018, pages 1-17.
Crossref
Zuoxu Hou, Yaguang Zhou, Hongyan Yang, Yan Liu, Xuechao Mao, Xinghua Qin, Xiaoliang Li, Xing Zhang & Yuanyuan Hu. (2018) Alpha7 nicotinic acetylcholine receptor activation protects against myocardial reperfusion injury through modulation of autophagy. Biochemical and Biophysical Research Communications 500:2, pages 357-364.
Crossref
Shuai Mao, Peipei Chen, Ting Li, Liheng Guo & Minzhou Zhang. (2018) Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1. Frontiers in Physiology 9.
Crossref
Bryce G. Johnson, Lan T. Dang, Graham Marsh, Allie M. Roach, Zebulon G. Levine, Anthony Monti, Deepak Reyon, Lionel Feigenbaum & Jeremy S. Duffield. (2017) Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis. Journal of Clinical Investigation 127:11, pages 3954-3969.
Crossref
José Manuel Bravo-San PedroGuido KroemerLorenzo Galluzzi. (2017) Autophagy and Mitophagy in Cardiovascular Disease. Circulation Research 120:11, pages 1812-1824.
Crossref
Eleonora Foglio, Giovanni Puddighinu, Antonia Germani, Matteo A. Russo & Federica Limana. (2017) HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition. Journal of Cellular Physiology 232:5, pages 1135-1143.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.