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Natural Product Research
Formerly Natural Product Letters
Volume 21, 2007 - Issue 14
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Original Articles

Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin

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Pages 1234-1241 | Received 13 Oct 2006, Accepted 09 Jan 2007, Published online: 12 Dec 2007

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Monojit Bhattacharjee, Suryaa Manoharan, Umamaheswari Sathisaran, Anand Tamatam & Ekambaram Perumal. (2023) MAO inhibiting phytochemicals from the roots of Glycyrrhiza glabra L.. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-19.
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M. Alagawany, S.S. Elnesr & M.R. Farag. (2019) Use of liquorice (Glycyrrhiza glabra) in poultry nutrition: Global impacts on performance, carcass and meat quality. World's Poultry Science Journal 75:2, pages 293-304.
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A. Karkanis, N. Martins, S.A. Petropoulos & I.C.F.R. Ferreira. (2018) Phytochemical composition, health effects, and crop management of liquorice (Glycyrrhiza glabra L.): Α medicinal plant. Food Reviews International 34:2, pages 182-203.
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Mingyan Liao, Yudan Zhao, Lizi Huang, Biao Cheng & Kun Huang. (2016) Isoliquiritigenin and liquiritin from Glycyrrhiza uralensis inhibit α-synuclein amyloid formation. RSC Advances 6:89, pages 86640-86649.
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Changyuan Wang, Xingping Duan, Xue Sun, Zhihao Liu, Pengyuan Sun, Xiaobo Yang, Huijun Sun, Kexin Liu & Qiang Meng. (2016) Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice. Food & Function 7:9, pages 3716-3723.
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T. K. LimT. K. Lim. 2016. Edible Medicinal and Non-Medicinal Plants. Edible Medicinal and Non-Medicinal Plants 354 457 .
Tarık Akman, Mustafa Guven, Adem Bozkurt Aras, Adile Ozkan, Halil Murat Sen, Ali Okuyucu, Yildiray Kalkan, Ibrahim Sehitoglu, Coskun Silan & Murat Cosar. (2015) The Neuroprotective Effect of Glycyrrhizic Acid on an Experimental Model of Focal Cerebral Ischemia in Rats. Inflammation 38:4, pages 1581-1588.
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Crossref
Hui Liu, Jinan Wang, Wei Zhou, Yonghua Wang & Ling Yang. (2013) Systems approaches and polypharmacology for drug discovery from herbal medicines: An example using licorice. Journal of Ethnopharmacology 146:3, pages 773-793.
Crossref
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Crossref
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Crossref
Eiko Kato, Yuichi Sasaki & Noriko Takahashi. (2011) Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE2 production in keratinocytes induced by UVB, IL-1β and peroxidants. Bioorganic & Medicinal Chemistry 19:21, pages 6348-6355.
Crossref
Kishor Vasant Otari, Rajkumar Virbhadrappa Shete, Rupesh Nandkumar Bhutada & Chandrashekhar Devidas Upasani. (2011) Effect of ammonium glycyrrhizinate on haloperidol- and reserpine- induced neurobehavioral alterations in experimental paradigms. Oriental Pharmacy and Experimental Medicine 11:3, pages 153-160.
Crossref
Bruno Burlando, Luisella Verotta, Laura Cornara & Elisa Bottini-Massa. 2010. Herbal Principles in Cosmetics. Herbal Principles in Cosmetics 41 372 .
Rosanna Di Paola, Marta Menegazzi, Emanuela Mazzon, Tiziana Genovese, Concetta Crisafulli, Martina Dal Bosco, Zhenzhen Zou, Hisanori Suzuki & Salvatore Cuzzocrea. (2008) Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model. Intensive Care Medicine 35:4, pages 687-697.
Crossref
Dnyaneshwar Umrao Bawankule, Dayanandan Mani, Anirban Pal, Karuna ShankerNarayan Prasad Yadav, Sachidanand Yadav, Amit Kumar Srivastava, Jyoti Agarwal, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Madan Mohan GuptaSuman Preet Singh Khanuja. (2009) Immunopotentiating Effect of an Ayurvedic Preparation from Medicinal Plants. Journal of Health Science 55:2, pages 285-289.
Crossref

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