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Natural Product Research
Formerly Natural Product Letters
Volume 21, 2007 - Issue 14
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Original Articles

First isolation of sesquiterpenes and flavonoids from Zingiber spectabile and identification of zerumbone as the major cell growth inhibitory component

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Pages 1242-1247 | Received 21 Dec 2006, Accepted 05 Oct 2007, Published online: 12 Dec 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Narges Hosseini, Amineh Khoshnazar, Massoud Saidijam, Farid Azizi Jalilian, Rezvan Najafi, Ali Mahdavinezhad, Razie Ezati, Alireza Sotanian & Razieh Amini. (2019) Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFκB-uPA Pathway. Nutrition and Cancer 71:1, pages 159-171.
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Y. Sivasothy, K. Awang, H. Ibrahim, K.L. Thong, N. Fitrah, X.P. Koh & L.K. Tan. (2012) Chemical composition and antibacterial activities of essential oils from Zingiber spectabile Griff. Journal of Essential Oil Research 24:3, pages 305-313.
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Articles from other publishers (16)

Hari Prasad Devkota, Keshav Raj Paudel, Md. Mahadi Hassan, Amina Ibrahim Dirar, Niranjan Das, Anjana Adhikari-Devkota, Javier Echeverría, Rajan Logesh, Niraj Kumar Jha, Sachin Kumar Singh, Philip M. Hansbro, Yinghan Chan, Dinesh Kumar Chellappan & Kamal Dua. (2021) Bioactive Compounds from Zingiber montanum and Their Pharmacological Activities with Focus on Zerumbone. Applied Sciences 11:21, pages 10205.
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Shaymaa Fadhel ABBAS ALBAAYİT, Mariam KHAN & Rasedee ABDULLAH. (2021) Zerumbone induces growth inhibition of Burkitt’s lymphoma cell line via apoptosis. Natural Volatiles and Essential Oils 8:3, pages 56-63.
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Yuen Ping Tan, Andrei I. Savchenko, Kylie A. Agnew-Francis, Glen M. Boyle, Paul V. Bernhardt, James A. Fraser & Craig M. Williams. (2020) Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian Dysphania Species That Suggests a Putative Biogenetic Link to Zerumbone . Journal of Natural Products 83:5, pages 1473-1479.
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Md. Mahadi Hassan, Anjana Adhikari-Devkota, Teruko Imai & Hari Prasad Devkota. (2019) Zerumbone and Kaempferol Derivatives from the Rhizomes of Zingiber montanum (J. Koenig) Link ex A. Dietr. from Bangladesh. Separations 6:2, pages 31.
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Fatemeh Karimi Dermani, Razieh Amini, Massoud Saidijam, Mona Pourjafar, Sahar Saki & Rezvan Najafi. (2018) Retracted : Zerumbone inhibits epithelial‐mesenchymal transition and cancer stem cells properties by inhibiting the β‐catenin pathway through miR‐200c . Journal of Cellular Physiology 233:12, pages 9538-9547.
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Thomas Sithara, B. P. Dhanya, K. B. Arun, Suresh Sini, Mathew Dan, Radhakrishnan Kokkuvayil Vasu & P. Nisha. (2018) Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells . Journal of Agricultural and Food Chemistry 66:3, pages 602-612.
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Md. Areeful Haque, Ibrahim Jantan, Laiba Arshad & Syed Nasir Abbas Bukhari. (2017) Exploring the immunomodulatory and anticancer properties of zerumbone. Food & Function 8:10, pages 3410-3431.
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T. K. LimT. K. Lim. 2016. Edible Medicinal and Non-Medicinal Plants. Edible Medicinal and Non-Medicinal Plants 561 576 .
You-Cheng Hseu, Yu-Chi Huang, Mallikarjuna Korivi, Jia-Jiuan Wu, Tzong-Der Way, Ting-Tsz Ou, Li-Wen Chiu, Chuan-Chen Lee, Meng-Liang Lin & Hsin-Ling Yang. (2015) Zerumbone attenuates TGF-β1-mediated epithelial–mesenchymal transition via upregulated E-cadherin expression and downregulated Smad2 signalling pathways in non-small cell lung cancer (A549) cells. Journal of Functional Foods 18, pages 58-72.
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Heshu Sulaiman Rahman, Abdullah Rasedee, Max Stanley Chartrand, Hemn Hassan Othman, Swee Keong Yeap & Farideh Namvar. (2014) Zerumbone Induces G2/M Cell Cycle Arrest and Apoptosis via Mitochondrial Pathway in Jurkat cell Line. Natural Product Communications 9:9, pages 1934578X1400900.
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Heshu Sulaiman Rahman, Abdullah Rasedee, Swee Keong Yeap, Hemn Hassan Othman, Max Stanley Chartrand, Farideh Namvar, Ahmad Bustamam Abdul & Chee Wun How. (2014) Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials. BioMed Research International 2014, pages 1-20.
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Yasodha Sivasothy, Shaida Fariza Sulaiman, Kheng Leong Ooi, Halijah Ibrahim & Khalijah Awang. (2013) Antioxidant and antibacterial activities of flavonoids and curcuminoids from Zingiber spectabile Griff.. Food Control 30:2, pages 714-720.
Crossref
Yasodha Sivasothy, A. Hamid A. Hadi, Khalit Mohamad, Kok Hoong Leong, Halijah Ibrahim, Shaida Fariza Sulaiman, Kheng Leong Ooi & Khalijah Awang. (2012) Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff.. Bioorganic & Medicinal Chemistry Letters 22:11, pages 3831-3836.
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Yong Qin Chang, Swee Ngin Tan, Jean W. H. Yong & Liya Ge. (2011) Surfactant‐assisted pressurized liquid extraction for determination of flavonoids from Costus speciosus by micellar electrokinetic chromatography . Journal of Separation Science 34:4, pages 462-468.
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Firoj Ahmed, Samir Kumar Sadhu & Masami Ishibashi. (2010) Search for bioactive natural products from medicinal plants of Bangladesh. Journal of Natural Medicines 64:4, pages 393-401.
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S. Fakurazi, I. Hairuszah, J. Mohd Lip, G. Shanthi, U. Nanthini, A.R. Shamima, H. Roslida & Y.H. Tan. (2009) Hepatoprotective Action of Zerumbone Against Paracetamol Induced Hepatotoxicity. Journal of Medical Sciences 9:3, pages 161-164.
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