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Natural Product Research
Formerly Natural Product Letters
Volume 22, 2008 - Issue 8
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Original Articles

Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice

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Pages 672-680 | Received 23 Sep 2007, Accepted 23 Nov 2007, Published online: 19 May 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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He Sun, Yueguang Xie & Jari Lavonen. (2022) Effects of the use of ICT in schools on students’ science higher-order thinking skills: comparative study of China and Finland. Research in Science & Technological Education 0:0, pages 1-18.
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Soo-Jin Kim, Mi-Sun Sung, Hwan Heo, Jae-Hyuk Lee & Sang-Woo Park. (2016) Mangiferin Protects Retinal Ganglion Cells in Ischemic Mouse Retina via SIRT1. Current Eye Research 41:6, pages 844-855.
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Peramaiyan Rajendran, Thamaraiselvan Rengarajan, Natarajan Nandakumar, H. Divya & Ikuo Nishigaki. (2015) Mangiferin in cancer chemoprevention and treatment: pharmacokinetics and molecular targets. Journal of Receptors and Signal Transduction 35:1, pages 76-84.
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Articles from other publishers (34)

Tusheema Dutta, Tuyelee Das, Abilash Valsala Gopalakrishnan, Suchismita Chatterjee Saha, Mimosa Ghorai, Samapika Nandy, Manoj Kumar, Radha, Arabinda Ghosh, Nobendu Mukerjee & Abhijit Dey. (2023) Mangiferin: the miraculous xanthone with diverse pharmacological properties. Naunyn-Schmiedeberg's Archives of Pharmacology 396:5, pages 851-863.
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Ilakya Selvakumar, Ashwini Vasudevan, Nirmal Perera, Meran Ediriweera, Devipriya Nagarajan, Sameera Samarakoon, Kamani Tennekoon & Vadivel Vellingiri. (2022) Mangifera indica and Mangifera zeylanica : Perspectives on medicinal properties, therapeutic applications and potential uses as anticancer epigenetic drugs (Review) . International Journal of Epigenetics 2:1.
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Rebai Ben Ammar, Fatma J. Al Saeedi, Emad A. Ahmed & Peramaiyan Rajendran. 2022. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 463 476 .
Min Liu, Chengquan Wen & Shengqi Pan. (2021) Modulator effect of mangiferin on biochemical characterization in 7,12‐dimethylbenz[a]anthracene induced oral cancer in experimental hamsters. Veterinary Medicine and Science 7:5, pages 2015-2025.
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Peramaiyan Rajendran, Abdullah M. Alzahrani, Emad A. Ahmed & Vishnu Priya Veeraraghavan. (2021) Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway. Oxidative Medicine and Cellular Longevity 2021, pages 1-13.
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Mohammad Bani Ismail, Peramaiyan Rajendran, Hamad Mohammed AbuZahra & Vishnu Priya Veeraraghavan. (2021) Mangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling Pathway. International Journal of Molecular Sciences 22:8, pages 4259.
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Saurabh Mittal, Mohammad Kashif Iqubal, Babar Iqbal, Madan Mohan Gupta, Javed Ali & Sanjula Baboota. (2021) A pervasive scientific overview on mangiferin in the prevention and treatment of various diseases with preclinical and clinical updates. Journal of Complementary and Integrative Medicine 18:1, pages 9-21.
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Fatma J. Al‐Saeedi. (2020) Mangiferin protect oxidative stress against deoxynivalenol induced damages through Nrf2 signalling pathways in endothelial cells. Clinical and Experimental Pharmacology and Physiology 48:3, pages 389-400.
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Karim Naraki, Ramin Rezaee, Habibeh Mashayekhi‐Sardoo, A. Wallace Hayes & Gholamreza Karimi. (2020) Mangiferin offers protection against deleterious effects of pharmaceuticals, heavy metals, and environmental chemicals. Phytotherapy Research 35:2, pages 810-822.
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Svetlana N. Morozkina, Thi Hong Nhung Vu, Yuliya E. Generalova, Petr P. Snetkov & Mayya V. Uspenskaya. (2021) Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems—A Novel Research Direction. Biomolecules 11:1, pages 79.
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Rebai Ben Ammar, Fatma J. Al Saeedi, Emad A. Ahmed & Peramaiyan Rajendran. 2020. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects 1 14 .
Khalid Z. Masoodi, Insha Amin, Sheikh Mansoor, Nazeer Ahmed, Volkan Altay & Munir Ozturk. 2020. Biodiversity and Biomedicine. Biodiversity and Biomedicine 189 234 .
Cuike Gong, Lei Qi, Yanxia Huo, Shiran Zhang, Xuecong Ning, Linlin Bai & Zhihua Wang. (2019) Anticancer effect of Limonin against benzo(a)pyrene‐induced lung carcinogenesis in Swiss albino mice and the inhibition of A549 cell proliferation through apoptotic pathway. Journal of Biochemical and Molecular Toxicology 33:12.
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Haiyan Yang, Hongsheng Zhang, Teng Pan, Haiyu Wang & Yadong Wang. (2018) Benzo(a)pyrene promotes migration, invasion and metastasis of lung adenocarcinoma cells by upregulating TGIF. Toxicology Letters 294, pages 11-19.
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Manjeshwar Shrinath Baliga, Suresh Rao, Pratima Rao, Krishnaprasad, Sanath Kumar Hegde, Kandel Codi Jalaluddin Akbar, Soniya Abraham, Thomas George & Princy Louis Palatty. 2018. Anticancer plants: Properties and Application. Anticancer plants: Properties and Application 57 76 .
Hu Wang, Yang-Yang Zhu, Li Wang, Tian Teng, Meng Zhou, Shu-Guang Wang, Yi-Zhu Tian, Lei Du, Xiao-Xing Yin & Ying Sun. (2017) Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice. Biomedicine & Pharmacotherapy 96, pages 328-335.
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김미경. (2017) Comparison of Antioxidant and Antimicrobial Activities of Pulp and Peel Extracts of Mango. Journal of Investigative Cosmetology 13:2, pages 113-118.
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Sukanya Saha, Pritam Sadhukhan & Parames C. Sil. (2016) Mangiferin: A xanthonoid with multipotent anti-inflammatory potential. BioFactors 42:5, pages 459-474.
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Maria T. S. Trevisan, Ricardo Farias de Almeida, Gabriela Soto, Elias De Melo Virginio Filho, Cornelia M. Ulrich & Robert W. Owen. (2016) Quantitation by HPLC-UV of Mangiferin and Isomangiferin in Coffee (Coffea arabica) Leaves from Brazil and Costa Rica After Solvent Extraction and Infusion. Food Analytical Methods 9:9, pages 2649-2655.
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Anna V. Kudryavtseva, George S. Krasnov, Alexey A. Dmitriev, Boris Y. Alekseev, Olga L. Kardymon, Asiya F. Sadritdinova, Maria S. Fedorova, Anatoly V. Pokrovsky, Nataliya V. Melnikova, Andrey D. Kaprin, Alexey A. Moskalev & Anastasiya V. Snezhkina. (2016) Mitochondrial dysfunction and oxidative stress in aging and cancer. Oncotarget 7:29, pages 44879-44905.
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Van L. T. Hoang, David J. Innes, P. Nicholas Shaw, Gregory R. Monteith, Michael J. Gidley & Ralf G. Dietzgen. (2015) Sequence diversity and differential expression of major phenylpropanoid-flavonoid biosynthetic genes among three mango varieties. BMC Genomics 16:1.
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Magdy Mahmoud-Awny, Ahmed S. Attia, Mohamed F. Abd-Ellah & Hanan Salah El-Abhar. (2015) Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways. PLOS ONE 10:7, pages e0132497.
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Van Le Thu Hoang, Jean-Thomas Pierson, Merril Carmel Curry, Paul Nicholas Shaw, Ralf Georg Dietzgen, Michael John Gidley, Sarah Jane Roberts-Thomson & Gregory Raymond Monteith. (2015) Polyphenolic contents and the effects of methanol extracts from mango varieties on breast cancer cells. Food Science and Biotechnology 24:1, pages 265-271.
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G. Ruiz-Montañez, J.A. Ragazzo-Sánchez, M. Calderón-Santoyo, G. Velázquez-de la Cruz, J.A. Ramírez de León & A. Navarro-Ocaña. (2014) Evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels (Mangifera indica L.). Food Chemistry 159, pages 267-272.
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Mandeep Kaur & H. K. Sharma. 2014. Functional Foods and Dietary Supplements. Functional Foods and Dietary Supplements 91 111 .
Joydeb Kumar Kundu & Kyung-Soo Chun. (2014) The Promise of Dried Fruits in Cancer Chemoprevention. Asian Pacific Journal of Cancer Prevention 15:8, pages 3343-3352.
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X. Zhang, B. Su, J. Li, Y. Li, D. Lu, K. Zhu, H. Pei & M. Zhao. (2012) Analysis by RP-HPLC of Mangiferin Component Correlation between Medicinal Loranthus and their Mango Host Trees. Journal of Chromatographic Science 52:1, pages 1-4.
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Joydeb Kumar Kundu & Young‐Joon Surh. 2013. Dried Fruits. Dried Fruits 19 51 .
Fenglei Luo, Qiang Lv, Yuqin Zhao, Guibing Hu, Guodi Huang, Jiukai Zhang, Chongde Sun, Xian Li & Kunsong Chen. (2012) Quantification and Purification of Mangiferin from Chinese Mango (Mangifera indica L.) Cultivars and Its Protective Effect on Human Umbilical Vein Endothelial Cells under H2O2-induced Stress. International Journal of Molecular Sciences 13:9, pages 11260-11274.
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Aamir Ahmad, Subhash Padhye & Fazlul H. Sarkar. 2012. Nutraceuticals and Cancer. Nutraceuticals and Cancer 179 199 .
Lim T. K.T. K. Lim. 2012. Edible Medicinal and Non-Medicinal Plants. Edible Medicinal and Non-Medicinal Plants 87 120 .
Dagmar García-Rivera, René Delgado, Nadia Bougarne, Guy Haegeman & Wim Vanden Berghe. (2011) Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells. Cancer Letters 305:1, pages 21-31.
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Giuliana D. Noratto, Michele C. Bertoldi, Kimberley Krenek, Stephen T. Talcott, Paulo C. Stringheta & Susanne U. Mertens-Talcott. (2010) Anticarcinogenic Effects of Polyphenolics from Mango (Mangifera indica) Varieties. Journal of Agricultural and Food Chemistry 58:7, pages 4104-4112.
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Sônia Machado Rocha Ribeiro & Andreas Schieber. 2010. Bioactive Foods in Promoting Health. Bioactive Foods in Promoting Health 507 523 .

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