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Natural Product Research
Formerly Natural Product Letters
Volume 26, 2012 - Issue 11
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Short Communications

Allicin induces apoptosis in EL-4 cells in vitro by activation of expression of caspase-3 and -12 and up-regulation of the ratio of Bax/Bcl-2

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Pages 1033-1037 | Received 15 Jun 2010, Accepted 22 Dec 2010, Published online: 09 Sep 2011

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Xiang Li, Jiahui Ni, Yixin Tang, Xu Wang, Huanhuan Tang, Haidong Li, Sulin Zhang & Xiaoyan Shen. (2019) Allicin inhibits mouse colorectal tumorigenesis through suppressing the activation of STAT3 signaling pathway. Natural Product Research 33:18, pages 2722-2725.
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Vivek D. Savairam, Neha A. Patil, Shrikant R. Borate, Mahesh M. Ghaisas & Rajkumar V. Shete. (2023) Allicin: A review of its important pharmacological activities. Pharmacological Research - Modern Chinese Medicine 8, pages 100283.
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Elena Catanzaro, Donatella Canistro, Valentina Pellicioni, Fabio Vivarelli & Carmela Fimognari. (2022) Anticancer potential of allicin: A review. Pharmacological Research 177, pages 106118.
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Wen Xu, Xiang-peng Li, En-ze Li, Yue-fen Liu, Jun Zhao, Li-na Wei & Lin Ma. (2020) Protective Effects of Allicin on ISO-Induced Rat Model of Myocardial Infarction via JNK Signaling Pathway. Pharmacology 105:9-10, pages 505-513.
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Xintian Shao, Qixin Chen, Xixi Dou, Lei Chen, Jixu Wu, Wei Zhang, Huarong Shao, Peixue Ling, Fei Liu & Fengshan Wang. (2018) Lower range of molecular weight of xanthan gum inhibits cartilage matrix destruction via intrinsic bax-mitochondria cytochrome c-caspase pathway. Carbohydrate Polymers 198, pages 354-363.
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Bahareh Mohammadi Jobani, Nowruz Najafzadeh, Mohammad Mazani, Mohsen Arzanlou & Mohammad Mohammadzadeh Vardin. (2018) Molecular mechanism and cytotoxicity of allicin and all-trans retinoic acid against CD44+ versus CD117+ melanoma cells. Phytomedicine 48, pages 161-169.
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Ariane Roseblade, Alison Ung & Mary Bebawy. (2017) Synthesis and in vitro biological evaluation of thiosulfinate derivatives for the treatment of human multidrug-resistant breast cancer. Acta Pharmacologica Sinica 38:10, pages 1353-1368.
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Fenrong Chen, Hong Li, Yan Wang, Meili Gao, Yan Cheng, Dong Liu, Miao Jia & Jun Zhang. (2016) Inhibition of allicin in Eca109 and EC9706 cells via G2/M phase arrest and mitochondrial apoptosis pathway. Journal of Functional Foods 25, pages 523-536.
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Farrokh Farhadi, Salar Jahanpour, Kameliya Hazem, Amirala Aghbali, Behzad Baradran & Seyyed Mahdi Vahid Pakdel. (2015) Garlic (Allium sativum) Fresh Juice Induces Apoptosis in Human Oral Squamous Cell Carcinoma: The Involvement of Caspase-3, Bax and Bcl-2. Journal of Dental Research, Dental Clinics, Dental Prospects 9:4, pages 267-273.
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Hongrui Guo, Lian Chen, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang & Bangyuan Wu. (2015) Research Advances on Pathways of Nickel-Induced Apoptosis. International Journal of Molecular Sciences 17:1, pages 10.
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Virginia Lanzotti, Felice Scala & Giuliano Bonanomi. (2014) Compounds from Allium species with cytotoxic and antimicrobial activity. Phytochemistry Reviews 13:4, pages 769-791.
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Md Soriful Islam, Most Mauluda Akhtar, Andrea Ciavattini, Stefano Raffaele Giannubilo, Olga Protic, Milijana Janjusevic, Antonio Domenico Procopio, James H. Segars, Mario Castellucci & Pasquapina Ciarmela. (2014) Use of dietary phytochemicals to target inflammation, fibrosis, proliferation, and angiogenesis in uterine tissues: Promising options for prevention and treatment of uterine fibroids?. Molecular Nutrition & Food Research 58:8, pages 1667-1684.
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Phoebe Zapanta Trio, Sixiang You, Xi He, Jianhua He, Kozue Sakao & De-Xing Hou. (2014) Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds. Food & Function 5:5, pages 833.
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Wei Jiang, Yong Huang, Jing-Peng Wang, Xiao-Yun Yu & Lin-Yi Zhang. (2013) The Synergistic Anticancer Effect of Artesunate Combined with Allicin in Osteosarcoma Cell Line in Vitro and in Vivo. Asian Pacific Journal of Cancer Prevention 14:8, pages 4615-4619.
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Jackie Yan-Yan Chan, Ailsa Chui-Ying Yuen, Robbie Yat-Kan Chan & Shun-Wan Chan. (2013) A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin. Phytotherapy Research 27:5, pages 637-646.
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