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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 16
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Short Communication

Baicalin induces apoptosis in human osteosarcoma cell through ROS-mediated mitochondrial pathway

Daqian WanDepartment of Orthopedics, Orthopedic Institute of Harbin, The Fifth Hospital in Harbin, Harbin, PR China
&
Huoniu OuyangDepartment of Neurosurgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR ChinaCorrespondence[email protected]
Pages 1996-2000 | Received 07 Jun 2017, Accepted 02 Jul 2017, Published online: 05 Sep 2017

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Qi-Jin Lu, Jia-Yu Li, Hong-Xin Lin, Yi-Si Cai, Chang-Shun Liu, Li-Ping Fu, Gang Liu & Li-Xia Yuan. (2022) Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosis. Pharmaceutical Biology 60:1, pages 1606-1615.
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Alaa Ibrahim, Sara A. Abdel Gaber, Mohamed Fawzi Kabil, Omar A.H. Ahmed-Farid, Anna K.H. Hirsch, Ibrahim M. El-Sherbiny & Maha Nasr. (2022) Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation. Expert Opinion on Drug Delivery 19:11, pages 1549-1560.
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Lin Wang, Ting Feng, Zhilian Su, Chao Pi, Yumeng Wei & Ling Zhao. (2022) Latest research progress on anticancer effect of baicalin and its aglycone baicalein. Archives of Pharmacal Research 45:8, pages 535-557.
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He Pang, Tingrui Wu, Zhonghua Peng, Qichao Tan, Xin Peng, Zeyu Zhan, Lijun Song & Bo Wei. (2022) Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways. Journal of Bone Oncology 33, pages 100415.
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Ana Carolina Silveira Rabelo, Jéssica Borghesi & Giuliana D. Noratto. (2021) The role of dietary polyphenols in osteosarcoma: A possible clue about the molecular mechanisms involved in a process that is just in its infancy. Journal of Food Biochemistry 46:1.
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Cláudia Pinto, Honorina Cidade, Madalena Pinto & Maria Elizabeth Tiritan. (2021) Chiral Flavonoids as Antitumor Agents. Pharmaceuticals 14:12, pages 1267.
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Shilpi Singh, Abha Meena & Suaib Luqman. (2021) Baicalin mediated regulation of key signaling pathways in cancer. Pharmacological Research 164, pages 105387.
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Jie Shen, Pei Li, Shuangshuang Liu, Qing Liu, Yue Li, Yuhua Sun, Chunnian He & Peigen Xiao. (2021) Traditional uses, ten-years research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria. Journal of Ethnopharmacology 265, pages 113198.
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Chun Zhang, Ping Yu, Jing Ma, Liang Zhu, Ajing Xu & Jian Zhang. (2019) Damage and Phenotype Change in PC12 Cells Induced by Lipopolysaccharide Can Be Inhibited by Antioxidants Through Reduced Cytoskeleton Protein Synthesis. Inflammation 42:6, pages 2246-2256.
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Yu Liu, Zhenqiang Hong, Peng Chen, Jinzhao Wang, Yimin Zhou & Jianyun Huang. (2019) Baicalin inhibits growth and induces apoptosis of human osteosarcoma cells by suppressing the AKT pathway. Oncology Letters.
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Aruo Nan, Lijian Chen, Nan Zhang, Yangyang Jia, Xin Li, Hanyu Zhou, Yihui Ling, Zhishan Wang, Chengfeng Yang, Sijin Liu & Yiguo Jiang. (2018) Circular RNA circNOL10 Inhibits Lung Cancer Development by Promoting SCLM1‐Mediated Transcriptional Regulation of the Humanin Polypeptide Family. Advanced Science 6:2.
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Xuanyuan Lu, Wei He, Wanlei Yang, Jianlei Li, Weiqi Han, Qian Liu, Tan Zhang, Jiawei Jiang, An Qin & Yu Qian. (2018) Dual effects of baicalin on osteoclast differentiation and bone resorption. Journal of Cellular and Molecular Medicine 22:10, pages 5029-5039.
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Xin Liu, Zhiming Ma, Jingxiao Zhang & Longfei Yang. (2017) Antifungal Compounds against Candida Infections from Traditional Chinese Medicine . BioMed Research International 2017, pages 1-12.
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