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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 18
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Short Communications

Xanthatin mediates G2/M cell cycle arrest, autophagy and apoptosis via ROS/XIAP signaling in human colon cancer cells

Ya-di GengDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaView further author information
,
Lei ZhangDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaView further author information
,
Guo-Yu WangDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaView further author information
,
Xiao-Jun FengDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaView further author information
,
Zhao-Lin ChenDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaView further author information
,
Ling JiangDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaCorrespondence[email protected] [email protected]
View further author information
&
Ai-Zong ShenDepartment of Pharmacy, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, ChinaCorrespondence[email protected] [email protected]
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Pages 2616-2620 | Received 02 Jul 2018, Accepted 29 Oct 2018, Published online: 27 Dec 2018

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Luis Miguel Guamán-Ortiz, Natalia Bailon-Moscoso, Vladimir Morocho, Daisy Vega-Ojeda, Fernando Gordillo & Alírica I. Suárez. (2021) Onoseriolide, from Hedyosmum racemosum, induces cytotoxicity and apoptosis in human colon cancer cells. Natural Product Research 35:18, pages 3151-3155.
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Yuan He, Dongyu Lei, Qingqing Yang, Hao Qi, Kurax Almira, Dilnigar Askar, Lu Jin & Le Pan. (2021) X anthium Orientale subsp. Italicum (Moretti) Greuter: bioassay-guided isolation and its chemical basis of antitumor cytotoxicity. Natural Product Research 35:14, pages 2433-2437.
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Articles from other publishers (11)

Yunxiao Liu, Xinge Zhang, Fenting Cheng, Wei Cao, Yadi Geng, Zhaolin Chen, Wei Wei & Lei Zhang. (2023) Xanthatin induce DDP‐resistance lung cancer cells apoptosis through regulation of GLUT1 mediated ROS accumulation. Drug Development Research.
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Huaqing Chen, Tong Zhu, Xiaojie Huang, Wenshuang Xu, Zemin Di, Yuyang Ma, Min Xue, Sixing Bi, Yujun Shen, Yongqiang Yu, Yuxian Shen & Lijie Feng. (2022) Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K‐Akt–mTOR pathway. Pharmacology Research & Perspectives 11:1.
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Yuanqi Liu, Wenyu Chen, Fang Zheng, Huanan Yu & Kun Wei. (2022) Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation. Molecules 27:14, pages 4603.
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Yulia Kirdeeva, Olga Fedorova, Alexandra Daks, Nikolai Barlev & Oleg Shuvalov. (2022) How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?. Pharmaceuticals 15:7, pages 868.
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Yanbo Xie, Xueyu Zhu, Ping Liu, Yunxiao Liu, Yadi Geng & Lei Zhang. (2022) Xanthatin inhibits non‐small cell lung cancer proliferation by breaking the redox balance. Drug Development Research.
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Yadi Geng, Lingli Li, Ping Liu, Zhaolin Chen, Aizong Shen & Lei Zhang. (2022) TMT-Based Quantitative Proteomic Analysis Identified Proteins and Signaling Pathways Involved in the Response to Xanthatin Treatment in Human HT-29 Colon Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry 22:5, pages 887-896.
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Lingli Li, Ping Liu, Yanbo Xie, Yunxiao Liu, Zhaolin Chen, Yadi Geng & Lei Zhang. (2021) Xanthatin inhibits human colon cancer cells progression via mTOR signaling mediated energy metabolism alteration . Drug Development Research 83:1, pages 119-130.
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Jian Zhang, Sheng Yang, Hongmei Guan, Jueyu Zhou & Yuan Gao. (2021) Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells. Journal of Cellular and Molecular Medicine 25:3, pages 1688-1699.
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Huailu Tu & Max Costa. (2020) XIAP’s Profile in Human Cancer. Biomolecules 10:11, pages 1493.
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Shangguan Jian, Liang Chen, Lian Minxue, Che Hongmin, Tang Ronghua, Fan Xiaoxuan, Zhang Binbin & Guo Shiwen. (2020) Tanshinone I induces apoptosis and protective autophagy in human glioblastoma cells via a reactive oxygen species‑dependent pathway. International Journal of Molecular Medicine.
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Jiquan Wang, Yingbing Zhang, Xu Liu, Jizhao Wang, Bin Li, Yongkang Liu & Jiansheng Wang. (2019) Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway. International Journal of Molecular Medicine.
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