Advanced search
Publication Cover
Expert Review of Anti-infective Therapy Volume 19, 2021 - Issue 1
Submit an article Journal homepage
5,333
Views
24
CrossRef citations to date
0
Altmetric
Special Report

Hydroxychloroquine in the COVID-19 pandemic era: in pursuit of a rational use for prophylaxis of SARS-CoV-2 infection

Marco Infantea Division of Endocrinology, CTO Andrea Alesini Hospital, ASL Roma 2, Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, Italy;b UniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy;c Diabetes Research Institute Federation (DRIF), Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, Italy;d Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Rome, Italy;e Diabetes Research Institute (DRI), University of Miami Miller School of Medicine, Miami, FL, USACorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0003-2032-8735View further author information
ORCID Icon,
Camillo Ricordie Diabetes Research Institute (DRI), University of Miami Miller School of Medicine, Miami, FL, USAView further author information
,
Rodolfo Alejandroe Diabetes Research Institute (DRI), University of Miami Miller School of Medicine, Miami, FL, USAView further author information
,
Massimiliano Capriof Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Rome, Italy;g Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, ItalyView further author information
&
Andrea Fabbria Division of Endocrinology, CTO Andrea Alesini Hospital, ASL Roma 2, Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, Italy;c Diabetes Research Institute Federation (DRIF), Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, ItalyView further author information
Pages 5-16 | Received 17 Jun 2020, Accepted 20 Jul 2020, Published online: 16 Aug 2020

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Haseeb Nisar, Bilal Wajid, Faria Anwar, Ashfaq Ahmad, Anum Javaid, Syed Awais Attique, Wardah Nisar, Amir Saeed, Samiah Shahid & Saima Sadaf. (2023) Bioinformatics and systems biology analysis revealed PMID26394986-Compound-10 as potential repurposable drug against covid-19. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-14.
Read now
Marco Infante, Andrea Buoso, Massimo Pieri, Santina Lupisella, Marzia Nuccetelli, Sergio Bernardini, Andrea Fabbri, Marco Iannetta, Massimo Andreoni, Vittorio Colizzi & Maria Morello. (2022) Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study. Journal of the American Nutrition Association 41:3, pages 250-265.
Read now
Narimana Imanova Yaghji, Elif Kilic Kan, Songul Akcan, Ramis Colak & Aysegul Atmaca. (2021) Hydroxychloroquine Sulfate Related Hypoglycemia In A Non-Diabetic COVİD-19 Patient: A Case Report and Literature Review. Postgraduate Medicine 133:5, pages 548-551.
Read now
Ankit Jain, Shiv Kumar Prajapati, Madhavi Tripathi, Ashok M. Raichur & Jagat R. Kanwar. (2021) Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights. Expert Review of Clinical Pharmacology 14:6, pages 715-734.
Read now
Raphael B Stricker & Melissa C Fesler. (2020) Flattening the Risk: Pre-Exposure Prophylaxis for COVID-19. Infection and Drug Resistance 13, pages 3689-3694.
Read now

Articles from other publishers (19)

Shikha Chaudhary, Arti Joshi, Kishore Sesham, Preeti Rai, Shailendra Kumar, Asit Ranjan Mridha, Upendra Baitha, Tapas Chandra Nag & Subhash Chandra Yadav. (2023) Impact of prophylactic hydroxychloroquine on ultrastructural impairment and cellular SARS-CoV-2 infection in different cells of bronchoalveolar lavage fluids of COVID-19 patients. Scientific Reports 13:1.
Crossref
Guiling Zhou, Stefan Verweij, Maarten J Bijlsma, Stijn de Vos, Katrien Oude Rengerink, Anna Maria Gerdina Pasmooij, Debbie van Baarle, Hubert G M Niesters, Peter Mol, Judith M Vonk & Eelko Hak. (2023) Repurposed drug studies on the primary prevention of SARS-CoV-2 infection during the pandemic: systematic review and meta-analysis. BMJ Open Respiratory Research 10:1, pages e001674.
Crossref
Hwanhee Hong, Anne Friedland, Mengyi Hu, Kevin J Anstrom, Susan Halabi, John E McKinnon, Ravi Amaravadi, Jorge Rojas-Serrano, Benjamin S Abella, Angélica Margarita Portillo-Vázquez, Christopher W Woods, Adrian F Hernandez, David R Boulware, Susanna Naggie & Radha Rajasingham. (2023) Safety and efficacy of hydroxychloroquine as prophylactic against COVID-19 in healthcare workers: a meta-analysis of randomised clinical trials. BMJ Open 13:6, pages e065305.
Crossref
Adam C. Delgado, Brendon Cornett, Ye Ji Choi, Christina Colosimo, Vincent P. Stahel, Oliwier Dziadkowiec & Philip F. Stahel. (2023) Investigational medications in 9,638 hospitalized patients with severe COVID-19: lessons from the “fail-and-learn” strategy during the first two waves of the pandemic in 2020. Patient Safety in Surgery 17:1.
Crossref
Taghreed S Saeed Al-Rawi & Raid M Al-Ani. (2023) Liver dysfunction-related COVID-19: A narrative review. World Journal of Meta-Analysis 11:1, pages 5-17.
Crossref
Ghanshyam Parmar, Jay Mukesh Chudasama, Ashish Shah & Ashish Patel. 2023. CADD and Informatics in Drug Discovery. CADD and Informatics in Drug Discovery 253 281 .
Lubaba Shahrin, Mustafa Mahfuz, Md. Waliur Rahman, Md. Rezaul Hossain, Afsana Mim Khandaker, Md. Ashraful Alam, Din M. M. F. Osmany, Md. Munirul Islam, Mohammod Jobayer Chisti, Chaudhury Meshkat Ahmed & Tahmeed Ahmed. (2022) Hospital-Based Quasi-Experimental Study on Hydroxychloroquine Pre-Exposure Prophylaxis for COVID-19 in Healthcare Providers with Its Potential Side-Effects. Life 12:12, pages 2047.
Crossref
Mosleh M. Abomughaid, Mohammed S. Nofal, Khaled I. Ghaleb, Mohamed G. Seadawy, Miral G. AbdEl-Wahab, Alaa S. Hegazy & Doaa A. Ghareeb. (2022) ZnO-chlorogenic acid nanostructured complex inhibits Covid-19 pathogenesis and increases hydroxychloroquine efficacy. Journal of King Saud University - Science 34:8, pages 102296.
Crossref
Noha F. El Azab. (2022) A validated UHPLC-MS/MS method for simultaneous quantification of some repurposed COVID-19 drugs in rat plasma: Application to a pharmacokinetic study. Microchemical Journal 178, pages 107321.
Crossref
Marco Infante, Nathalia Padilla, Rodolfo Alejandro, Massimiliano Caprio, David Della-Morte, Andrea Fabbri & Camillo Ricordi. (2022) Diabetes-Modifying Antirheumatic Drugs: The Roles of DMARDs as Glucose-Lowering Agents. Medicina 58:5, pages 571.
Crossref
Fuxiaonan Zhao, Jianhai Wang, Qi Wang, Zhili Hou, Yingchao Zhang, Xue Li, Qi Wu & Huaiyong Chen. (2022) Organoid technology and lung injury mouse models evaluating effects of hydroxychloroquine on lung epithelial regeneration. Experimental Animals 71:3, pages 316-328.
Crossref
Dania Altulea, Sjors Maassen, Maksim V Baranov & G van den Bogaart. (2021) What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology. Journal of Molecular Cell Biology 13:3, pages 175-184.
Crossref
Donovan A. McGrowder, Fabian Miller, Melisa Anderson Cross, Lennox Anderson-Jackson, Sophia Bryan & Lowell Dilworth. (2021) Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis. Diseases 9:3, pages 50.
Crossref
Hang Xu, Xiang Yang Zhang, Wei Wen Wang & Jiesi Wang. (2021) Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain. Frontiers in Pharmacology 12.
Crossref
Urszula Abramczyk & Aleksandra Kuzan. (2021) What Every Diabetologist Should Know about SARS-CoV-2: State of Knowledge at the Beginning of 2021. Journal of Clinical Medicine 10:5, pages 1022.
Crossref
Aikaterini Thanou & Amr H. Sawalha. (2021) SARS-CoV-2 and Systemic Lupus Erythematosus. Current Rheumatology Reports 23:2.
Crossref
Zelyn LeeCraig R. RaynerJamie I. ForrestJean B. NachegaEsha SenchaudhuriEdward J. Mills. (2021) The Rise and Fall of Hydroxychloroquine for the Treatment and Prevention of COVID-19. The American Journal of Tropical Medicine and Hygiene 104:1, pages 35-38.
Crossref
Marina Laplana, Oriol Yuguero & Joan Fibla. (2020) Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients. PLOS ONE 15:12, pages e0243598.
Crossref
Cosima Rughiniş, Lorena Dima & Sorina Vasile. (2020) Hydroxychloroquine and COVID-19: Lack of Efficacy and the Social Construction of Plausibility. American Journal of Therapeutics 27:6, pages e573-e583.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.