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Expert Review of Anti-infective Therapy Volume 19, 2021 - Issue 5
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Review

Sepsis in the critically ill patient: current and emerging management strategies

Nicholas Heminga Department of Intensive Care, Raymond Poincaré Hospital, GHU APHP Université Paris Saclay, Garches, France;b Laboratory Inflammation & Infection, U1173, School of Medicine Simone Veil, Université Paris Saclay-UVSQ and - INSERM 2 Avenue De La Source De La Bièvre, Montigny-le-Bretonneux, France;c FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for SEPSIS);d RHU RECORDS (Rapid rEcognition of CORticosteroiD Resistant or Sensitive Sepsis)View further author information
,
Eric Azaboub Laboratory Inflammation & Infection, U1173, School of Medicine Simone Veil, Université Paris Saclay-UVSQ and - INSERM 2 Avenue De La Source De La Bièvre, Montigny-le-Bretonneux, France;c FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for SEPSIS);d RHU RECORDS (Rapid rEcognition of CORticosteroiD Resistant or Sensitive Sepsis);e Clinical Neurophysiology and Neuromodulation Unit, Department of Physiology, Raymond Poincaré Hospital, GHU APHP Université Paris Saclay, Garches, FranceView further author information
,
Xavier Cazaumayoua Department of Intensive Care, Raymond Poincaré Hospital, GHU APHP Université Paris Saclay, Garches, FranceView further author information
,
Pierre Moinea Department of Intensive Care, Raymond Poincaré Hospital, GHU APHP Université Paris Saclay, Garches, France;b Laboratory Inflammation & Infection, U1173, School of Medicine Simone Veil, Université Paris Saclay-UVSQ and - INSERM 2 Avenue De La Source De La Bièvre, Montigny-le-Bretonneux, France;c FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for SEPSIS);d RHU RECORDS (Rapid rEcognition of CORticosteroiD Resistant or Sensitive Sepsis)View further author information
&
Djillali Annanea Department of Intensive Care, Raymond Poincaré Hospital, GHU APHP Université Paris Saclay, Garches, France;b Laboratory Inflammation & Infection, U1173, School of Medicine Simone Veil, Université Paris Saclay-UVSQ and - INSERM 2 Avenue De La Source De La Bièvre, Montigny-le-Bretonneux, France;c FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for SEPSIS);d RHU RECORDS (Rapid rEcognition of CORticosteroiD Resistant or Sensitive Sepsis)Correspondence[email protected]
View further author information
Pages 635-647 | Received 25 Jul 2020, Accepted 02 Nov 2020, Published online: 23 Nov 2020

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Chenglin Wang, Yang Li, Shilin Li, Muhu Chen & Yingchun Hu. (2022) Proteomics Combined with RNA Sequencing to Screen Biomarkers of Sepsis. Infection and Drug Resistance 15, pages 5575-5587.
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Articles from other publishers (9)

Chengwu Gong, Jinlong Wu, Hao Li, Congcong Luo, Guangyu Ji, Xin Guan, Jichun Liu & Mingsong Wang. (2023) METTL3 achieves lipopolysaccharide-induced myocardial injury via m6A-dependent stabilization of Myh3 mRNA. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1870:7, pages 119503.
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Yuanyuan Li, Weina Wang, Bo Zhang, Lili LiDengfeng Zhou. (2023) A bibliometric analysis of exosomes in sepsis from 2004 to 2022. Medicine 102:31, pages e34613.
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Tianyang Hu, Wanjun Yao, Yu Li & Yanan Liu. (2023) Interaction of acute heart failure and acute kidney injury on in-hospital mortality of critically ill patients with sepsis: A retrospective observational study. PLOS ONE 18:3, pages e0282842.
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Zhixi Li, Yongjing Yu, Chang Liu, Guangmin Chen, Weidong Gong, Juan Luo & Ziyong Yue. (2022) Identification of the key ferroptosis-related genes involved in sepsis progression and experimental validation in vivo. Frontiers in Pharmacology 13.
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Joshua Yu & Timothy Veenstra. 2022. Protein Detection. Protein Detection.
B. C. Srimedha, Rashmi Naveen Raj & Veena Mayya. (2022) A Comprehensive Machine Learning Based Pipeline for an Accurate Early Prediction of Sepsis in ICU. IEEE Access 10, pages 105120-105132.
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V. V. Kulabukhov, N. A. Zubareva & P. A. Yartsev. (2021) Sepsis: source control. Messenger of ANESTHESIOLOGY AND RESUSCITATION 18:5, pages 89-96.
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Josep Bringué, Raquel Guillamat-Prats, Maria Martinez, Eva Torrents, Marta Camprubí-Rimblas, Lluís Blanch & Antonio Artigas. (2021) Methotrexate Ameliorates Systemic Inflammation and Septic Associated-Lung Damage in a Cecal Ligation and Puncture Septic Rat Model. International Journal of Molecular Sciences 22:17, pages 9612.
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Peng Luo, Cai-xia Song, Ye-qing Ai, Zhe Chen, Sheng-nan Yan, Xia Liu, Ying Chen & Jia-bin Sun. (2021) Evaluation of the association between extravascular lung water and prognosis of sepsis. Medicine 100:5, pages e23971.
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