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Original Articles

Solvent-Free Synthesis of Pyrimidine Nucleoside-Aminophosphonate Hybrids and Their Biological Activity Evaluation

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Pages 616-627 | Received 26 Jan 2010, Accepted 21 May 2010, Published online: 19 Jul 2010

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MohamedF. Abdel-Megeed, BadrE. Badr, MohamedM. Azaam & GamalA. El-Hiti. (2012) Synthesis and Antimicrobial Activities of Diphenyl(Arylamino)(1-Phenyl-3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Methylphosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements 187:12, pages 1462-1468.
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Jiaoli Ma, Jing Li, Penghu Guo, Xincheng Liao & Huicheng Cheng. (2021) Synthesis and antitumor activity of novel indole derivatives containing α-aminophosphonate moieties. Arabian Journal of Chemistry 14:8, pages 103256.
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Weihua Li, Yifeng Wang & Danqian Xu. (2018) Asymmetric Synthesis of α-Amino Phosphonates by Using Cinchona Alkaloid-Based Chiral Phase Transfer Catalyst. European Journal of Organic Chemistry 2018:39, pages 5422-5426.
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Shailee Tiwari, Nawaz Sharif, Rekha Gajare, Julio Vazquez, Jaiprakash Sangshetti, Manoj Damale & Anna Nikalje. (2018) New 2-Oxoindolin Phosphonates as Novel Agents to Treat Cancer: A Green Synthesis and Molecular Modeling. Molecules 23:8, pages 1981.
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Kolio D. Troev. 2018. Reactivity of P-H Group of Phosphorus Based Compounds. Reactivity of P-H Group of Phosphorus Based Compounds 291 409 .
Esmaeil Mohammadiyan, Hossein Ghafuri & Ali Kakanejadifard. (2017) A new procedure for synthesis of $$\upalpha $$ α -aminophosphonates by aqueous formic acid as an effective and environment-friendly organocatalyst. Journal of Chemical Sciences 129:12, pages 1883-1891.
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Peter Mbugua Njogu, John Okombo & Kelly Chibale. 2017. Design of Hybrid Molecules for Drug Development. Design of Hybrid Molecules for Drug Development 83 135 .
Hossein Ghafuri, Afsaneh Rashidizadeh & Hamid Reza Esmaili Zand. (2016) Highly efficient solvent free synthesis of α-aminophosphonates catalyzed by recyclable nano-magnetic sulfated zirconia (Fe 3 O 4 @ZrO 2 /SO 4 2− ) . RSC Advances 6:19, pages 16046-16054.
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Shenghai Guo, Jiliang Wang, Xinying Zhang, Sandrine Cojean, Philippe M. Loiseau & Xuesen Fan. (2015) Synthesis of 5-isoxazol-3-yl-pyrimidine nucleosides as potential antileishmanial agents. Bioorganic & Medicinal Chemistry Letters 25:13, pages 2617-2620.
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El-Refaie S. Kenawy, Mohamed M. Azaam & Khalil M. Saad-Allah. (2015) Synthesis and antimicrobial activity of α-aminophosphonates containing chitosan moiety. Arabian Journal of Chemistry 8:3, pages 427-432.
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Mariola Koszytkowska-Stawińska & Włodzimierz Buchowicz. (2014) Multicomponent reactions in nucleoside chemistry. Beilstein Journal of Organic Chemistry 10, pages 1706-1732.
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SANTHOSH REDDY MANDHA, MANJULA ALLA & VITTAL RAO BOMMENA. (2014) Water mediated eco-friendly green protocol for one-pot synthesis of α-aminophosphonates at ambient conditions. Journal of Chemical Sciences 126:3, pages 793-799.
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Srikant Bhagat, Parth Shah, Sanjeev K. Garg, Shweta Mishra, Preet Kamal Kaur, Sushma Singh & Asit K. Chakraborti. (2014) α-Aminophosphonates as novel anti-leishmanial chemotypes: synthesis, biological evaluation, and CoMFA studies. Med. Chem. Commun. 5:5, pages 665-670.
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Mohamed F. Abdel-Megeed, Mohamed M. Azaam & Gamal A. El-Hiti. (2013) Diphenyl (4′-(Aryldiazenyl)biphenyl-4-ylamino)(pyridin-3-yl)methylphosphonates as Azo Disperse Dyes for Dyeing Polyester Fabrics. Journal of Chemistry 2013, pages 1-5.
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Mohamed F. Abdel-Megeed, Badr E. Badr, Mohamed M. Azaam & Gamal A. El-Hiti. (2012) Synthesis and Antimicrobial Activities of a Novel Series of Heterocyclic α-Aminophosphonates. Archiv der Pharmazie 345:10, pages 784-789.
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Mohamed F. Abdel-Megeed, Badr E. Badr, Mohamed M. Azaam & Gamal A. El-Hiti. (2012) Synthesis, antimicrobial and anticancer activities of a novel series of diphenyl 1-(pyridin-3-yl)ethylphosphonates. Bioorganic & Medicinal Chemistry 20:7, pages 2252-2258.
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Xinying Zhang, Yingying Qu, Xuesen Fan, C. Bores, Dong Feng, Graciela Andrei, Robert Snoeck, Erik De Clercq & Philippe M. Loiseau. (2011) ChemInform Abstract: Solvent‐Free Synthesis of Pyrimidine Nucleoside‐Aminophosphonate Hybrids and Their Biological Activity Evaluation.. ChemInform 42:5.
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