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Adriana M. Torres, Ankur V. Dnyanmote, Jeffry C. Granados & Sanjay K. Nigam. (2021) Renal and non-renal response of ABC and SLC transporters in chronic kidney disease. Expert Opinion on Drug Metabolism & Toxicology 17:5, pages 515-542.
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Chikayuki Morimoto, Yoshifuru Tamura, Shinichiro Asakawa, Emiko Kuribayashi-Okuma, Yoshikazu Nemoto, Jinping Li, Takayo Murase, Takashi Nakamura, Makoto Hosoyamada, Shunya Uchida & Shigeru Shibata. (2020) ABCG2 expression and uric acid metabolism of the intestine in hyperuricemia model rat. Nucleosides, Nucleotides & Nucleic Acids 39:5, pages 744-759.
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Xianxiang Xu, Canghai Li, Pan Zhou & Tingliang Jiang. (2016) Uric acid transporters hiding in the intestine. Pharmaceutical Biology 54:12, pages 3151-3155.
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Articles from other publishers (59)
Emmanuel A. Adomako & Orson W. Moe. (2023) Uric acid transport, transporters, and their pharmacological targeting. Acta Physiologica 238:2.
Crossref
Crossref
Paniagua-Díaz Natsuko, Sanchez-Chapul Laura, Clavijo-Cornejo Denise, Ventura-Ríos Lucio, Aguilar-Salinas Carlos, Sanchez-Muñoz Fausto & López-Macay Ambar. (2022) Differential gene expression of ABCG2, SLC22A12, IL-1β, and ALPK1 in peripheral blood leukocytes of primary gout patients with hyperuricemia and their comorbidities: a case–control study. European Journal of Medical Research 27:1.
Crossref
Crossref
Bendong Yang, Meiling Xin, Shufei Liang, Xiaoxue Xu, Tianqi Cai, Ling Dong, Chao Wang, Meng Wang, Yuting Cui, Xinhua Song, Jinyue Sun & Wenlong Sun. (2022) New insight into the management of renal excretion and hyperuricemia: Potential therapeutic strategies with natural bioactive compounds. Frontiers in Pharmacology 13.
Crossref
Crossref
Ya-Sian Chang, Chien-Yu Lin, Ting-Yuan Liu, Chung-Ming Huang, Chin-Chun Chung, Yu-Chia Chen, Fuu-Jen Tsai, Jan-Gowth Chang & Shun-Jen Chang. (2022) Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study. Arthritis Research & Therapy 24:1.
Crossref
Crossref
Christopher Jenkins, Jennifer H. Hwang, Jeffrey B. Kopp, Cheryl A. Winkler & Sung Kweon Cho. (2022) Review of Urate-Lowering Therapeutics: From the Past to the Future. Frontiers in Pharmacology 13.
Crossref
Crossref
Douglas H. Sweet. 2022. Drug Transporters. Drug Transporters
319
332
.
Regiane Stafim da Cunha, Carolina Amaral Bueno Azevedo, Carlos Alexandre Falconi, Fernanda Fogaça Ruiz, Sophie Liabeuf, Marcela Sorelli Carneiro-Ramos & Andréa Emilia Marques Stinghen. (2022) The Interplay between Uremic Toxins and Albumin, Membrane Transporters and Drug Interaction. Toxins 14:3, pages 177.
Crossref
Crossref
Huining Dai, Shuai Lv, Zi'an Qiao, Kaiyu Wang, Xipeng Zhou, Chunyang Bao, Shitao Zhang, Xueqi Fu & Wannan Li. (2022) The Active Components of Sunflower (Helianthus annuus L.) Calathide and the Effects on Urate Nephropathy Based on COX-2/PGE2 Signaling Pathway and the Urate Transporter URAT1, ABCG2, and GLUT9. Frontiers in Nutrition 8.
Crossref
Crossref
Ling Cao, Tianyi Zhao, Yu Xue, Luan Xue, Yueying Chen, Feng Quan, Yu Xiao, Weiguo Wan, Man Han, Quan Jiang, Liwei Lu, Hejian Zou & Xiaoxia Zhu. (2022) The Anti-Inflammatory and Uric Acid Lowering Effects of Si-Miao-San on Gout. Frontiers in Immunology 12.
Crossref
Crossref
Lei Zhao, Yihang Li, Dahong Yao, Ran Sun, Shifang Liu, Xi Chen, Congcong Lin, Jian Huang, Jinhui Wang & Guang Li. (2021) Pharmacological Basis for Use of a Novel Compound in Hyperuricemia: Anti-Hyperuricemic and Anti-Inflammatory Effects. Frontiers in Pharmacology 12.
Crossref
Crossref
I-Chieh Chen, Yen-Ju Chen, Yi-Ming Chen, Hsueh-Ju Lin, Ying-Cheng Lin, Jui-Chun Chagn, Pei-Chun Chen & Ching-Heng Lin. (2021) Interaction of Alcohol Consumption and ABCG2 rs2231142 Variant Contributes to Hyperuricemia in a Taiwanese Population. Journal of Personalized Medicine 11:11, pages 1158.
Crossref
Crossref
Chuanxi Sun, Shuqian Lin, Zhen Li, Huazheng Liu, Yixin Liu, Keke Wang, Tianyi Zhu, Guiming Li, Bin Yin & Renzhong Wan. (2021) iTRAQ-based quantitative proteomic analysis reveals the toxic mechanism of diclofenac sodium on the kidney of broiler chicken. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 249, pages 109129.
Crossref
Crossref
Dayeon Shin & Kyung Won Lee. (2021) Dietary Acid Load Is Positively Associated with the Incidence of Hyperuricemia in Middle-Aged and Older Korean Adults: Findings from the Korean Genome and Epidemiology Study. International Journal of Environmental Research and Public Health 18:19, pages 10260.
Crossref
Crossref
Asim K. Mandal, Megan P. Leask, Christopher Estiverne, Hyon K. Choi, Tony R. Merriman & David B. Mount. (2021) Genetic and Physiological Effects of Insulin on Human Urate Homeostasis. Frontiers in Physiology 12.
Crossref
Crossref
Samit Ganguly, David Finkelstein, Timothy I. Shaw, Ryan D. Michalek, Kimberly M. Zorn, Sean Ekins, Kazuto Yasuda, Yu Fukuda, John D. Schuetz, Kamalika Mukherjee & Erin G. Schuetz. (2021) Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters. PLOS ONE 16:7, pages e0253852.
Crossref
Crossref
Bianca Vora, Deanna J. Brackman, Ling Zou, Maria Garcia‐Cremades, Marina Sirota, Radojka M. Savic & Kathleen M. Giacomini. (2021) Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics. Clinical and Translational Science 14:4, pages 1431-1443.
Crossref
Crossref
Robert Eckenstaler & Ralf A. Benndorf. (2021) The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout—An Update. International Journal of Molecular Sciences 22:13, pages 6678.
Crossref
Crossref
Tamás Nagy, Ágota Tóth, Ágnes Telbisz, Balázs Sarkadi, Hedvig Tordai, Attila Tordai & Tamás Hegedűs. (2020) The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations. Cellular and Molecular Life Sciences 78:5, pages 2329-2339.
Crossref
Crossref
Utpal K. Mondal & Marc A. Ilies. 2021. pH-Interfering Agents as Chemosensitizers in Cancer Therapy. pH-Interfering Agents as Chemosensitizers in Cancer Therapy
95
120
.
Motohiro Sekiya, Takaaki Matsuda, Yuki Yamamoto, Yasuhisa Furuta, Mariko Ohyama, Yuki Murayama, Yoko Sugano, Yoshinori Ohsaki, Hitoshi Iwasaki, Naoya Yahagi, Shigeru Yatoh, Hiroaki Suzuki & Hitoshi Shimano. (2020) Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion. BMC Medical Genetics 21:1.
Crossref
Crossref
Kateryna Pierzynowska, Aditi Deshpande, Nadiia Mosiichuk, Robert Terkeltaub, Paulina Szczurek, Eduardo Salido, Stefan Pierzynowski & Danica Grujic. (2020) Oral Treatment With an Engineered Uricase, ALLN-346, Reduces Hyperuricemia, and Uricosuria in Urate Oxidase-Deficient Mice. Frontiers in Medicine 7.
Crossref
Crossref
Sho Wada, Norikazu Matsunaga & Ikumi Tamai. (2020) Mathematical modeling analysis of hepatic uric acid disposition using human sandwich-cultured hepatocytes. Drug Metabolism and Pharmacokinetics 35:5, pages 432-440.
Crossref
Crossref
Arshad Mehmood, Liang Zhao, Muhammad Ishaq, Muhammad Usman, Oumeddour Dounya Zad, Imam Hossain, Rifat Nowshin Raka, Muhammad Naveed, Lei Zhao, Chengtao Wang & Muhammad Nadeem. (2020) Uricostatic and uricosuric effect of grapefruit juice in potassium oxonate‐induced hyperuricemic mice. Journal of Food Biochemistry 44:7.
Crossref
Crossref
Lin-Feng Guo, Xue Chen, Shan-Shan Lei, Bo Li, Ning-Yu Zhang, Hong-Zhang Ge, Ke Yang, Gui-Yuan Lv & Su-Hong Chen. (2020)
Effects and Mechanisms of
Dendrobium officinalis
Six Nostrum for Treatment of Hyperuricemia with Hyperlipidemia
. Evidence-Based Complementary and Alternative Medicine 2020, pages 1-12.
Crossref
Crossref
Navaz Karimian Pour & Micheline Piquette-Miller. (2020) Dysregulation of renal transporters in a rodent model of viral Infection. International Immunopharmacology 80, pages 106135.
Crossref
Crossref
Erika Nagle, Nellija Luksa, Georgijs Moisejevs & Linda Gailīte. (2020) Risk Factor Analysis for Gout in the Latvian Population. Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 74:1, pages 7-11.
Crossref
Crossref
Michal Rozanski, Maciej Studzian & Lukasz Pulaski. (2019) Direct Measurement of Kinetic Parameters of ABCG2-Dependent Transport of Natural Flavonoids Using a Fluorogenic Substrate. Journal of Pharmacology and Experimental Therapeutics 371:2, pages 309-319.
Crossref
Crossref
Young-Sil Lee, Yoon-Young Sung, Heung Joo Yuk, Eunjung Son, SeonJoo Lee, Jin Soo Kim & Dong-Seon Kim. (2019) Anti-hyperuricemic effect of Alpinia oxyphylla seed extract by enhancing uric acid excretion in the kidney. Phytomedicine 62, pages 152975.
Crossref
Crossref
Marc Le Vée, Astrid Bacle, Elodie Jouan, Valérie Lecureur, Sophie Potin & Olivier Fardel. (2019) Induction of multidrug resistance-associated protein 3 expression by diesel exhaust particle extract in human bronchial epithelial BEAS-2B cells. Toxicology in Vitro 58, pages 60-68.
Crossref
Crossref
Liming Chen, Jose E. Manautou, Theodore P. Rasmussen & Xiao-bo Zhong. (2019) Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2. Acta Pharmaceutica Sinica B 9:4, pages 659-674.
Crossref
Crossref
Hong Shen, Renato J. Scialis & Lois Lehman-McKeeman. (2019) Xenobiotic Transporters in the Kidney: Function and Role in Toxicity. Seminars in Nephrology 39:2, pages 159-175.
Crossref
Crossref
Siwei Wang, Yuejuan Fang, Xinfen Yu, Lu Guo, Xiaoxi Zhang & Daozong Xia. (2019) The flavonoid-rich fraction from rhizomes of Smilax glabra Roxb. ameliorates renal oxidative stress and inflammation in uric acid nephropathy rats through promoting uric acid excretion. Biomedicine & Pharmacotherapy 111, pages 162-168.
Crossref
Crossref
Xiaodong Liu. 2019. Drug Transporters in Drug Disposition, Effects and Toxicity. Drug Transporters in Drug Disposition, Effects and Toxicity
13
100
.
Sabine Ottilie, Gregory M. Goldgof, Andrea L. Cheung, Jennifer L. Walker, Edgar Vigil, Kenneth E. Allen, Yevgeniya Antonova-Koch, Carolyn W. Slayman, Yo Suzuki & Jacob D. Durrant. (2018) Two inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies. Journal of Cheminformatics 10:1.
Crossref
Crossref
Hongbo Zhao, Yutang Huang, Jingjing Shi, Yi Dai, Lanxiang Wu & Honghao Zhou. (2018) ABCC10 Plays a Significant Role in the Transport of Gefitinib and Contributes to Acquired Resistance to Gefitinib in NSCLC. Frontiers in Pharmacology 9.
Crossref
Crossref
Jiaojiao Jing, Arif B. Ekici, Thomas Sitter, Kai-Uwe Eckardt, Elke Schaeffner, Yong Li, Florian Kronenberg, Anna Köttgen & Ulla T. Schultheiss. (2018) Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease. Scientific Reports 8:1.
Crossref
Crossref
Tianyi Zhao, Xiaoxi Lv, Ling Cao, Meizhu Guo, Shucong Zheng, Yu Xue, Hejian Zou, Weiguo Wan & Xiaoxia Zhu. (2018) Renal excretion is a cause of decreased serum uric acid during acute gout. International Journal of Rheumatic Diseases 21:9, pages 1723-1727.
Crossref
Crossref
Tomoya Yasujima, Chihiro Murata, Yoshihisa Mimura, Tomoaki Murata, Masahiko Ohkubo, Kinya Ohta, Katsuhisa Inoue & Hiroaki Yuasa. (2018) Urate transport function of rat sodium-dependent nucleobase transporter 1. Physiological Reports 6:10, pages e13714.
Crossref
Crossref
Kristin M. Bircsak, Jamie E. Moscovitz, Xia Wen, Faith Archer, Poi Yu Sofia Yuen, Moiz Mohammed, Naureen Memon, Barry I. Weinberger, Laura M. Saba, Anna M. Vetrano & Lauren M. Aleksunes. (2018)
Interindividual Regulation of the Breast Cancer Resistance Protein/
ABCG2
Transporter in Term Human Placentas
. Drug Metabolism and Disposition 46:5, pages 619-627.
Crossref
Crossref
Deanna J. Brackman & Kathleen M. Giacomini. (2018)
Reverse Translational Research of
ABCG2
(BCRP) in Human Disease and Drug Response
. Clinical Pharmacology & Therapeutics 103:2, pages 233-242.
Crossref
Crossref
Ferry Fredy Karwur & Dwi Rahayu Pujiastuti. (2017) Review Article: URIC ACID HOMEOSTASIS AND DISTURBANCES. Folia Medica Indonesiana 53:4, pages 292.
Crossref
Crossref
Anton Ivanyuk, Françoise Livio, Jérôme Biollaz & Thierry Buclin. (2017) Renal Drug Transporters and Drug Interactions. Clinical Pharmacokinetics 56:8, pages 825-892.
Crossref
Crossref
Szabolcs Tarapcsák, Gábor Szalóki, Ágnes Telbisz, Zsuzsanna Gyöngy, Krisztina Matúz, Éva Csősz, Péter Nagy, Imre J. Holb, Ralph Rühl, László Nagy, Gábor Szabó & Katalin Goda. (2017) Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein. Scientific Reports 7:1.
Crossref
Crossref
Katsuki Nishihashi, Kei Kawashima, Takami Nomura, Yumiko Urakami-Takebayashi, Makoto Miyazaki, Mikihisa Takano & Junya Nagai. (2017) Cobalt Chloride Induces Expression and Function of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Renal Proximal Tubular Epithelial Cell Line HK-2. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:1, pages 82-87.
Crossref
Crossref
Philip K. Tan, Traci M. Ostertag & Jeffrey N. Miner. (2016) Mechanism of high affinity inhibition of the human urate transporter URAT1. Scientific Reports 6:1.
Crossref
Crossref
Ming Wang, Jing Zhao, Nan Zhang & Jianghua Chen. (2016) Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice. Biomedicine & Pharmacotherapy 83, pages 975-988.
Crossref
Crossref
Juan Wang, Xiao-Xia Zhu, Lei Liu, Yu Xue, Xue Yang & He-Jian Zou. (2016) SIRT1 prevents hyperuricemia via the PGC-1α/PPARγ-ABCG2 pathway. Endocrine 53:2, pages 443-452.
Crossref
Crossref
Vibha Bhatnagar, Erin L. Richard, Wei Wu, Caroline M. Nievergelt, Michael S. Lipkowitz, Janina Jeff, Adam X. Maihofer & Sanjay K. Nigam. (2016) Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling. Clinical Kidney Journal 9:3, pages 444-453.
Crossref
Crossref
Xiang Liu, Shangqi Li, Wenzhu Peng, Shuaisheng Feng, Jianxin Feng, Shahid Mahboob, Khalid A. Al-Ghanim & Peng Xu. (2016) Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio). PLOS ONE 11:4, pages e0153246.
Crossref
Crossref
Febbie Sangkop, Geeta Singh, Ely Rodrigues, Elspeth Gold & Andrew Bahn. (2016) Uric acid: a modulator of prostate cells and activin sensitivity. Molecular and Cellular Biochemistry 414:1-2, pages 187-199.
Crossref
Crossref
Zheng Dong, Shicheng Guo, Yajun Yang, Junjie Wu, Ming Guan, Hejian Zou, Li Jin & Jiucun Wang. (2015) Association between ABCG2 Q141K polymorphism and gout risk affected by ethnicity and gender: a systematic review and meta-analysis. International Journal of Rheumatic Diseases 18:4, pages 382-391.
Crossref
Crossref
Yu Liang, Siqi Li & Ligong Chen. (2015) The physiological role of drug transporters. Protein & Cell 6:5, pages 334-350.
Crossref
Crossref
Zita Gál, Csilla Hegedüs, Gergely Szakács, András Váradi, Balázs Sarkadi & Csilla Özvegy-Laczka. (2015) Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:2, pages 477-487.
Crossref
Crossref
Ming-Xing Wang, Yang-Liu Liu, Ying Yang, Dong-Mei Zhang & Ling-Dong Kong. (2015) Nuciferine restores potassium oxonate-induced hyperuricemia and kidney inflammation in mice. European Journal of Pharmacology 747, pages 59-70.
Crossref
Crossref
J. R. Storry. (2014) Five new blood group systems - what next?. ISBT Science Series 9:1, pages 136-140.
Crossref
Crossref
Márton Jani, Csilla Ambrus, Rémi Magnan, Katalin Tauberné Jakab, Erzsébet Beéry, Joseph K. Zolnerciks & Péter Krajcsi. (2014) Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics. Archives of Toxicology 88:6, pages 1205-1248.
Crossref
Crossref
Chen-Yu Fan, Ming-Xing Wang, Chen-Xu Ge, Xing Wang, Jian-Mei Li & Ling-Dong Kong. (2014) Betaine supplementation protects against high-fructose-induced renal injury in rats. The Journal of Nutritional Biochemistry 25:3, pages 353-362.
Crossref
Crossref
Sijumon Kunjachan, Błażej Rychlik, Gert Storm, Fabian Kiessling & Twan Lammers. (2013) Multidrug resistance: Physiological principles and nanomedical solutions. Advanced Drug Delivery Reviews 65:13-14, pages 1852-1865.
Crossref
Crossref
Qing-Hua Hu, Ji-Xiao Zhu, Jing Ji, Lin-Lin Wei, Ming-Xing Miao & Hui Ji. (2013) Fructus Gardenia Extract Ameliorates Oxonate-Induced Hyperuricemia with Renal Dysfunction in Mice by Regulating Organic Ion Transporters and mOIT3. Molecules 18:8, pages 8976-8993.
Crossref
Crossref