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Original Articles

Design, Synthesis, Antiviral, and Cytotoxic Evaluation of Novel Phosphonylated 1,2,3-Triazoles as Acyclic Nucleotide Analogues

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Pages 293-318 | Received 24 Nov 2011, Accepted 27 Jan 2012, Published online: 23 Mar 2012

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Yi-ning Wen, Zhi-feng Zhang, Ning-ning Liu, Yu-hong Xiang, Zhuo-yong Zhang, Graciela Andrei, Robert Snoeck, Dominique Schols, Qing-shan Zhang & Qin-pei Wu. (2016) Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides. Nucleosides, Nucleotides & Nucleic Acids 35:3, pages 147-160.
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Anna Zdzienicka, Dominique Schols, Graciela Andrei, Robert Snoeck & Iwona E. Głowacka. (2015) Phosphonylated 8-Azahypoxantines as Acyclic Nucleotide Analogs. Phosphorus, Sulfur, and Silicon and the Related Elements 190:12, pages 2207-2221.
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Articles from other publishers (19)

Lingaiah Bontha, Praveen Kumar Edigi, Appaji Dokala, Divya Pingili, Venkat Reddy Putta, Ravi kumar Vuradi, Laxma Reddy Kotha & Satyanarayana Sirasani. (2023) Synthesis, in-silico based virtual screening,anti-cancer potential of novel1,2,3-triazole-thiadiazole hybrid derivatives as Aurora kinase A (ARK-A) and Extracellular regulated kinase 2 (ERK2) dual inhibitors. Medicinal Chemistry Research 32:11, pages 2419-2431.
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Iwona E. Głowacka, Katarzyna Gawron, Dorota G. Piotrowska, Mirthe Graus, Graciela Andrei, Dominique Schols, Robert Snoeck, Anita Camps, Emiel Vanhulle & Kurt Vermeire. (2023) Design and synthesis of a new series of hybrids of functionalised N1-[(1H-1,2,3-triazol-4-yl)methyl]quinazoline-2,4-dione with antiviral activity against Respiratory Syncytial Virus. Antiviral Research 209, pages 105518.
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SOUMIA BELKHARCHACH, HANA IGHACHANE, ABDESSADEK LACHGAR, MUSTAPHA AIT ALI & HASSAN B LAZREK. (2020) Efficient and selective catalytic N-Alkylation of pyrimidine by ammonium Sulfate@Hydro-thermal carbone under eco-friendly conditions. Journal of Chemical Sciences 132:1.
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Guang Huan Shen & Joon Hee Hong. (2020) Chemical Synthesis of Acyclic Nucleoside Phosphonate Analogs Linked with Cyclic Systems between the Phosphonate and the Base Moieties. Current Medicinal Chemistry 27:35, pages 5918-5948.
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Anna Tripolszky, Krisztina Németh, Pál Tamás Szabó & Erika Bálint. (2019) Synthesis of (1,2,3-triazol-4-yl)methyl Phosphinates and (1,2,3-Triazol-4-yl)methyl Phosphates by Copper-Catalyzed Azide-Alkyne Cycloaddition. Molecules 24:11, pages 2085.
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Iwona E. Głowacka, Piotr Grzonkowski, Paweł Lisiecki, Łukasz Kalinowski & Dorota G. Piotrowska. (2019) Synthesis and antimicrobial activity of novel 1,2,3‐triazole‐conjugates of quinazolin‐4‐ones. Archiv der Pharmazie 352:3.
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C. P. Kaushik & Ashima Pahwa. (2017) Convenient synthesis, antimalarial and antimicrobial potential of thioethereal 1,4-disubstituted 1,2,3-triazoles with ester functionality. Medicinal Chemistry Research 27:2, pages 458-469.
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C.P. Kaushik & Raj Luxmi. (2017) Synthesis and Antimicrobial Activity of 2-(4-(Hydroxyalkyl)-1 H -1,2,3-triazol-1-yl)- N -substituted propanamides . Journal of Heterocyclic Chemistry 54:6, pages 3618-3625.
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Iwona Głowacka, Rafał Gulej, Piotr Grzonkowski, Graciela Andrei, Dominique Schols, Robert Snoeck & Dorota Piotrowska. (2016) Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates. Molecules 21:11, pages 1420.
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Dorota Rygielska-Tokarska, Graciela Andrei, Dominique Schols, Robert Snoeck & Iwona E. Głowacka. (2016) Synthesis, antiviral, cytotoxic and cytostatic evaluation of N 1-(phosphonoalkyl)uracil derivatives. Monatshefte für Chemie - Chemical Monthly 147:6, pages 1081-1090.
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Iwona Głowacka, Graciela Andrei, Dominique Schols, Robert Snoeck & Dorota Piotrowska. (2015) Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker. Molecules 20:10, pages 18789-18807.
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Hans Steenackers, Akanksha Dubey, Stijn Robijns, Denis Ermolat'ev, Nicolas Delattin, Barbara Dovgan, Lenart Girandon, Mirjam Fröhlich, Katrijn De Brucker, Bruno Cammue, Karin Thevissen, Jan Balzarini, Erik Van der Eycken & Jozef Vanderleyden. (2014) Evaluation of the Toxicity of 5-Aryl-2-Aminoimidazole-Based Biofilm Inhibitors against Eukaryotic Cell Lines, Bone Cells and the Nematode Caenorhabditis elegans. Molecules 19:10, pages 16707-16723.
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Iwona E. Głowacka, Jan Balzarini, Graciela Andrei, Robert Snoeck, Dominique Schols & Dorota G. Piotrowska. (2014) Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues. Bioorganic & Medicinal Chemistry 22:14, pages 3629-3641.
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Iwona E. Głowacka, Jan Balzarini & Andrzej E. Wróblewski. (2014) Novel Acyclic Phosphonylated 1,2,3-Triazolonucleosides with an Acetamidomethyl Linker: Synthesis and Biological Activity. Archiv der Pharmazie 347:7, pages 506-514.
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Emilia Bankowska, Jan Balzarini, Iwona E. Głowacka & Andrzej E. Wróblewski. (2014) Design, synthesis, antiviral and cytotoxic evaluation of novel acyclic phosphonate nucleotide analogues with a 5,6-dihydro-1H-[1,2,3]triazolo[4,5-d]pyridazine-4,7-dione system. Monatshefte für Chemie - Chemical Monthly 145:4, pages 663-673.
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Rodrigo González-Olvera, Araceli Espinoza-Vázquez, Guillermo Negrón-Silva, Manuel Palomar-Pardavé, Mario Romero-Romo & Rosa Santillan. (2013) Multicomponent Click Synthesis of New 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases: Promising Acidic Corrosion Inhibitors for Steel. Molecules 18:12, pages 15064-15079.
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Iwona E. Głowacka, Jan Balzarini & Andrzej E. Wróblewski. (2013) The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker. European Journal of Medicinal Chemistry 70, pages 703-722.
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Iwona E. Głowacka, Jan Balzarini & Andrzej E. Wróblewski. (2013) Synthesis of a New Series of Phosphonylated 1,2,3-Triazoles as Acyclic Analogs of Ribavirin. Archiv der Pharmazie 346:9, pages 677-687.
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Iwona E. Głowacka, Jan Balzarini & Andrzej E. Wróblewski. (2013) Synthesis and Biological Evaluation of Novel 1,2,3-Triazolonucleotides. Archiv der Pharmazie 346:4, pages 278-291.
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