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Original Articles

S-glycosides in medicinal chemistry: Novel synthesis of cyanoethylene thioglycosides and their pyrazole derivatives

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Pages 198-212 | Received 22 May 2015, Accepted 31 Oct 2016, Published online: 03 Jan 2017

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Read on this site (4)

Mamdouh A. Abu-Zaied, Galal H. Elgemeie, Fathi T. Halaweish & Sherif F. Hammad. (2022) Synthesis of novel pyridine and pyrimidine thioglycoside phosphoramidates for the treatment of COVID-19 and influenza A viruses. Nucleosides, Nucleotides & Nucleic Acids 41:9, pages 851-877.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2019) Novel synthesis of new pyrazole thioglycosides as pyrazomycin analogues. Nucleosides, Nucleotides & Nucleic Acids 38:5, pages 374-389.
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Galal H. Elgemeie, Mamdouh A. Abu-Zaied & Abdel-Tawab H. Mossa. (2019) Novel Synthesis and Biological Evaluation of the First Pyrazole Thioglycosides as Pyrazofurin Analogues. Nucleosides, Nucleotides & Nucleic Acids 38:3, pages 183-202.
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Mamdouh A. Abu-Zaied & Galal H. Elgemeie. (2018) A facile synthesis of novel pyrazolopyrimidine thioglycosides as purine thioglycoside analogues. Nucleosides, Nucleotides & Nucleic Acids 37:1, pages 67-77.
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Articles from other publishers (15)

Matteo Lusardi, Aldo Profumo, Chiara Rotolo, Erika Iervasi, Camillo Rosano, Andrea Spallarossa & Marco Ponassi. (2022) Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives. Molecules 27:18, pages 5814.
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Rasha A. Azzam, Galal H. Elgemeie, Nagwa M. Gad & Peter G. Jones. (2022) 4-Amino-5-(4-bromobenzoyl)-3-(benzo[ d ]thiazol-2-yl)-2-[(2′,3′,4′,6′-tetra- O -acetyl-β- D -galactopyranosyl)sulfanyl]thiophene . IUCrData 7:4.
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M. H. Sanad, Fawzy A. Marzook, Ayman B. Farag, Sudip Kumar Mandal, Syed F. A. Rizvi & Jeetendra Kumar Gupta. (2022) Preparation, biological evaluation and radiolabeling of [ 99m Tc]-technetium tricarbonyl procainamide as a tracer for heart imaging in mice . Radiochimica Acta 110:4, pages 267-277.
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M. H. Sanad, F. A. Marzook, S. K. Mandal & M. Baidya. (2022) Radiocomplexation and Biological Evaluation of [99mTc]Tricarbonyl Rabeprazole as a Radiotracer for Peptic Ulcer Localization. Radiochemistry 64:2, pages 211-218.
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H. M. Eyssa, Heba. M. El Refay & M. H. Sanad. (2022) Enhancement of the thermal and physicochemical properties of styrene butadiene rubber composite foam using nanoparticle fillers and electron beam radiation. Radiochimica Acta 110:3, pages 205-218.
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Matteo Lusardi, Chiara Rotolo, Marco Ponassi, Erika Iervasi, Camillo Rosano & Andrea Spallarossa. (2022) One‐Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives. ChemMedChem 17:5.
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M. H. Sanad, H. M. Eyssa, F. A. Marzook & A. B. Farag. (2022) Preparation and Bioevaluation of [99mTc]Tricarbonyl Omeprazole for Gastric Ulcer Localization in Mice. Radiochemistry 64:1, pages 54-61.
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M.H. Sanad, A.B. Farag, Sabry A. Bassem & F.A. Marzook. (2022) Radioiodination of zearalenone and determination of Lactobacillus plantarum effect of on zearalenone organ distribution: In silico study and preclinical evaluation. Toxicology Reports 9, pages 470-479.
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Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 547 611 .
Mamdouh A. Abu-Zaied, Galal H. Elgemeie & Nashwa M. Mahmoud. (2021) Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses. ACS Omega 6:26, pages 16890-16904.
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Mamdouh A. Abu-Zaied, Nashwa M. Mahmoud & Galal H. Elgemeie. (2020) Toward Developing Therapies against Corona Virus: Synthesis and Anti-Avian Influenza Virus Activity of Novel Cytosine Thioglycoside Analogues. ACS Omega 5:32, pages 20042-20050.
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Mamdouh Attia Abu-Zaied, Sherif F. Hammad, Fathi T. Halaweish & Galal Hamza Elgemeie. (2020) Sofosbuvir Thio-analogues: Synthesis and Antiviral Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside Phosphoramidates. ACS Omega 5:24, pages 14645-14655.
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Ali M. Hebishy, Galal H. Elgemeie, Hagar T. Salama & Peter G. Jones. (2019) 3-Ethoxy-5-phenyl-1 H -1,2,4-triazole . IUCrData 4:4.
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Rasha A. Azzam, Galal H. Elgemeie, Rasha E. Elsayed & Peter G. Jones. (2017) Crystal structure of N -[6-amino-5-(benzo[ d ]thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1,2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate . Acta Crystallographica Section E Crystallographic Communications 73:12, pages 1820-1822.
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Rasha A. Azzam, Galal H. Elgemeie, Rokia Ramadan & Peter G. Jones. (2017) Crystal structure of 2-cyano-3,3-bis(ethylsulfanyl)- N - o -tolylacrylamide . Acta Crystallographica Section E Crystallographic Communications 73:5, pages 752-754.
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