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Nucleosides, Nucleotides & Nucleic Acids Volume 36, 2017 - Issue 3
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Original Articles

Pyrimidine non-nucleoside analogs: A direct synthesis of a novel class of N-substituted amino and N-sulfonamide derivatives of pyrimidines

Galal H. ElgemeieChemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, EgyptCorrespondence[email protected]
,
Ali M. SalahChemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, Egypt
,
Nermeen S. AbbasChemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, Egypt;Chemistry Department, Faculty of Science, Taibah University, Saudi Arabia
,
Hoda A. HusseinPhotochemistry Department, National Research Center, Dokki, Cairo, Egypt
&
Reham A. MohamedPhotochemistry Department, National Research Center, Dokki, Cairo, Egypt
Pages 213-223 | Received 06 Feb 2016, Accepted 31 Oct 2016, Published online: 19 Jan 2017

Citations (16)

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Galal Elgemeie, Farag Altalbawy, Mohammed Alfaidi, Rania Azab & Atef Hassan. (2017) Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones. Drug Design, Development and Therapy 11, pages 3389-3399.
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Articles from other publishers (15)

Reham A. Mohamed-Ezzat, Benson M. Kariuki & Rasha A. Azzam. (2023) Synthesis and crystal structure of N -(5-acetyl-4-methylpyrimidin-2-yl)benzenesulfonamide . Acta Crystallographica Section E Crystallographic Communications 79:4, pages 331-334.
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Reihane Ghomashi, Shakila Ghomashi, Hamidreza Aghaei & Ahmad Reza Massah. (2023) Recent Advances in Biological Active Sulfonamide based Hybrid Compounds Part A: Two-Component Sulfonamide Hybrids. Current Medicinal Chemistry 30:4, pages 407-480.
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Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Mohammed A. Khedr & Gihad E. Elsherif. (2022) Medicinal Chemistry of Pyrazolopyrimidine Scaffolds Substituted with Different Heterocyclic Nuclei. Current Pharmaceutical Design 28:41, pages 3374-3403.
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Yunjian Wu, Shan Hu, Changyu Wu, Feng Gu & Ying Yang. (2022) Probiotics: Potential Novel Therapeutics Against Fungal Infections. Frontiers in Cellular and Infection Microbiology 11.
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Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Ashraf A. Aly, Nadia H. Metwally, Mona O. Sarhan, Elshimaa M. Abdelhafez & Rasha E. Elsayed. 2022. N-Sulfonated-N-Heterocycles. N-Sulfonated-N-Heterocycles 303 318 .
Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 547 611 .
Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 107 142 .
Jun-Ling Wang, Sen Ma, Pei-Zhi Zhang, Ai-Quan Jia & Qian-Feng Zhang. (2019) Syntheses and Crystal Structures of Methyl N-Substituted-N′-Cyanocarbamimidothioates Derived from Dimethyl N-Cyanodithioiminocarbonate. Journal of Chemical Crystallography 50:4, pages 295-302.
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Kaitlind C. Howard, Emily K. Dennis, David S. Watt & Sylvie Garneau-Tsodikova. (2020) A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise. Chemical Society Reviews 49:8, pages 2426-2480.
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Rasha A. Azzam, Rokia R. Osman & Galal H. Elgemeie. (2020) Efficient Synthesis and Docking Studies of Novel Benzothiazole-Based Pyrimidinesulfonamide Scaffolds as New Antiviral Agents and Hsp90α Inhibitors. ACS Omega 5:3, pages 1640-1655.
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Galal H. Elgemeie, Rasha A. Azzam & Rasha E. Elsayed. (2019) Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018). Medicinal Chemistry Research 28:8, pages 1099-1131.
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Ali M. Hebishy, Galal H. Elgemeie, Hagar T. Salama & Peter G. Jones. (2019) 3-Ethoxy-5-phenyl-1 H -1,2,4-triazole . IUCrData 4:4.
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Rasha A. Azzam, Galal H. Elgemeie, Rasha E. Elsayed & Peter G. Jones. (2017) Crystal structure of N -[6-amino-5-(benzo[ d ]thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1,2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate . Acta Crystallographica Section E Crystallographic Communications 73:12, pages 1820-1822.
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Rasha A. Azzam, Galal H. Elgemeie, Rasha E. Elsayed & Peter G. Jones. (2017) Crystal structure of N ′-[2-(benzo[ d ]thiazol-2-yl)acetyl]-4-methylbenzenesulfonohydrazide . Acta Crystallographica Section E Crystallographic Communications 73:7, pages 1041-1043.
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Rasha A. Azzam, Galal H. Elgemeie, Rokia Ramadan & Peter G. Jones. (2017) Crystal structure of 2-cyano-3,3-bis(ethylsulfanyl)- N - o -tolylacrylamide . Acta Crystallographica Section E Crystallographic Communications 73:5, pages 752-754.
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