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Nucleosides, Nucleotides & Nucleic Acids Volume 27, 2008 - Issue 6-7
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Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man (PP07)

Imatinib-Resistant CML Cells Have Low ENT Activity But Maintain Sensitivity to Gemcitabine

Andrea V. Leisewitz Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
,
Eric I. Zimmerman Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
,
Shannon Z. Jones Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
,
Jing Yang Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
&
Lee M. Graves Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA
Pages 779-786 | Published online: 03 Jul 2008

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Candido G Da Silva, Richard J Honeywell, Henk Dekker & Godefridus J Peters. (2015) Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters. Expert Opinion on Drug Metabolism & Toxicology 11:5, pages 703-717.
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Articles from other publishers (8)

Vijaya L. Damaraju, Dwayne Weber, Michelle Kuzma, Carol E. Cass & Michael B. Sawyer. (2016) Selective Inhibition of Human Equilibrative and Concentrative Nucleoside Transporters by BCR-ABL Kinase Inhibitors. Journal of Biological Chemistry 291:36, pages 18809-18817.
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V. Damaraju, D. Mowles, C. Cass & M. Sawyer. (2015) Comparison of Human Nucleoside Transporter Interactions with BCR-ABL Kinase Inhibitors. Annals of Oncology 26, pages ii33.
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Vijaya L. Damaraju, Michelle Kuzma, Delores Mowles, Carol E. Cass & Michael B. Sawyer. (2015) Interactions of Multitargeted Kinase Inhibitors and Nucleoside Drugs: Achilles Heel of Combination Therapy?. Molecular Cancer Therapeutics 14:1, pages 236-245.
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Vijaya L. Damaraju, Tara Scriver, Delores Mowles, Michelle Kuzma, Anderson J. Ryan, Carol E. Cass & Michael B. Sawyer. (2014) Erlotinib, Gefitinib, and Vandetanib Inhibit Human Nucleoside Transporters and Protect Cancer Cells from Gemcitabine Cytotoxicity. Clinical Cancer Research 20:1, pages 176-186.
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Josy S. Naud, Karim Ghani, Pedro O. de Campos-Lima & Manuel Caruso. (2012) Nilotinib and imatinib inhibit cytarabine cellular uptake: Implications for combination therapy. Leukemia Research 36:10, pages 1311-1314.
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Xianglan Lu, Xianfu Wang, Yougmi Kim, Rui Zhang, Shibo Li & Ji-Yun Lee. (2012) Acquired genomic copy number changes in CML patients with the Philadelphia chromosome (Ph+). Cancer Genetics 205:10, pages 513-518.
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Woon-Gye Chung, Michael A. Sandoval, Brian R. Sloat, Dharmika S.P. Lansakara-P & Zhengrong Cui. (2012) Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1. Journal of Controlled Release 157:1, pages 132-140.
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Andrea V. Leisewitz, Eric I. Zimmerman, Min Huang, Shannon Z. Jones, Jing Yang & Lee M. Graves. (2011) Regulation of ENT1 expression and ENT1-dependent nucleoside transport by c-Jun N-terminal kinase. Biochemical and Biophysical Research Communications 404:1, pages 370-375.
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