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Nucleosides, Nucleotides & Nucleic Acids Volume 29, 2010 - Issue 4-6
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Original Articles

The Activity of the Lipophilic Nucleoside Derivatives Elacytarabine and CP-4126 in a Panel of Tumor Cell Lines Resistant to Nucleoside Analogues

Marit Liland Sandvold Clavis Pharma, Oslo, Norway
,
Carlos Galmarini ENS-CNRS 5239, UFR Lyon-Sud, Oullins Cedex, France
,
Finn Myhren Clavis Pharma, Oslo, Norway
&
Godefridus Peters Department of Medical Oncology, VU University Medical Center, Amsterdam, the Netherlands
Pages 386-393 | Published online: 11 Jun 2010

Citations (14)

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Hanlan Liu, Jayaprakasam Bolleddula, Andrew Nichols, Lei Tang, Zhiyang Zhao & Chandra Prakash. (2020) Metabolism of bioconjugate therapeutics: why, when, and how?. Drug Metabolism Reviews 52:1, pages 66-124.
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Niamh Keane, Ciara Freeman, Ronan Swords & Francis J Giles. (2013) Elacytarabine: lipid vector technology under investigation in acute myeloid leukemia. Expert Review of Hematology 6:1, pages 9-24.
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GodefridusJ. Peters, AukeD. Adema, IreneV. Bijnsdorp & MaritL. Sandvold. (2011) Lipophilic Prodrugs and Formulations of Conventional (Deoxy)Nucleoside and Fluoropyrimidine Analogs in Cancer. Nucleosides, Nucleotides & Nucleic Acids 30:12, pages 1168-1180.
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Articles from other publishers (11)

Rajgopal Govindarajan, Antonio López Quiñones & Joanne Wang. 2022. Drug Transporters. Drug Transporters 165 187 .
Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 107 142 .
Nadia Fattahi, Mohammad-Ali Shahbazi, Aziz Maleki, Mehrdad Hamidi, Ali Ramazani & Hélder A. Santos. (2020) Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines. Journal of Controlled Release 326, pages 556-598.
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Bingjun Sun, Cong Luo, Weiping Cui, Jin Sun & Zhonggui He. (2017) Chemotherapy agent-unsaturated fatty acid prodrugs and prodrug-nanoplatforms for cancer chemotherapy. Journal of Controlled Release 264, pages 145-159.
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Peter Alexander, Gregory Kucera & Timothy S. Pardee. (2016) Improving nucleoside analogs via lipid conjugation: Is fatter any better?. Critical Reviews in Oncology/Hematology 100, pages 46-56.
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Horace T. B. Ho & Joanne Wang. 2014. Drug Transporters. Drug Transporters 107 126 .
Alice Mims & Robert K. Stuart. (2013) Developmental Therapeutics in Acute Myelogenous Leukemia: Are There Any New Effective Cytotoxic Chemotherapeutic Agents Out There?. Current Hematologic Malignancy Reports 8:2, pages 156-162.
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James D. Young, Sylvia Y.M. Yao, Jocelyn M. Baldwin, Carol E. Cass & Stephen A. Baldwin. (2013) The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Molecular Aspects of Medicine 34:2-3, pages 529-547.
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Elodie Moysan, Guillaume Bastiat & Jean-Pierre Benoit. (2012) Gemcitabine versus Modified Gemcitabine: A Review of Several Promising Chemical Modifications. Molecular Pharmaceutics 10:2, pages 430-444.
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Susan O'Brien, David A. Rizzieri, Norbert Vey, Farhad Ravandi, Utz O. Krug, Mikkael A. Sekeres, Mike Dennis, Adriano Venditti, Donald A. Berry, Tove Flem Jacobsen, Karin Staudacher, Trygve Bergeland & Francis J. Giles. (2012) Elacytarabine has single‐agent activity in patients 
with advanced acute myeloid leukaemia. British Journal of Haematology 158:5, pages 581-588.
Crossref
Francis Giles, David Rizzieri, Farhad Ravandi, Ronan Swords, Tove Flem Jacobsen & Susan O’Brien. (2012) Elacytarabine, a novel 5′-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia. Leukemia Research 36:4, pages e71-e73.
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