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Nucleosides and Nucleotides Volume 14, 1995 - Issue 3-5
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I. NUCLEOSIDES: Biophysics/Biochemistry

Ribonucleotide Reductase Targets for Chemotherapy; Mechanistic Aspects and Biologically Active Agents

Morris J. Robins Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, U.S.A.
,
Mirna C. Samano Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, U.S.A.; Burroughs Wellcome Co., Research Triangle Park, NC
&
Vicente Samano Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, 84602, U.S.A.; Burroughs Wellcome Co., Research Triangle Park, NC
Pages 485-493 | Published online: 16 Feb 2007

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Read on this site (2)

MorrisJ. Robins. (1999) Mechanism-Based Inhibition of Ribonucleotide Reductases: New Mechanistic Considerations and Promising Biological Applications. Nucleosides and Nucleotides 18:4-5, pages 779-793.
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RogersE. Harry-O'kuru, EmilyA. Kryjak & MichaelS. Wolfe. (1997) 2′-C-Alkylribonucleosides: Design, Synthesis, and Conformation. Nucleosides and Nucleotides 16:7-9, pages 1457-1460.
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Articles from other publishers (9)

Amos B. Smith III & Justin Potuzak. (2014) The 2010 Benjamin Franklin medal in chemistry presented to Joanne Stubbe. Journal of the Franklin Institute 351:1, pages 1-11.
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Pedro Alexandrino Fernandes & Maria João Ramos. (2003) Theoretical Studies on the Mechanism of Inhibition of Ribonucleotide Reductase by ( E )-2‘-Fluoromethylene-2‘-deoxycitidine-5‘-diphosphate . Journal of the American Chemical Society 125:20, pages 6311-6322.
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Zhiqiang Guo, Mirna C Samano, Jan W Krzykawski, Stanislaw F Wnuk, Gregory J Ewing & Morris J Robins. (1999) Biomimetic modeling of the abstraction of H3′ by ribonucleotide reductases. 1,5-Hydrogen atom transfer of H3 to aminyl and oxyl, but not thiyl, free radicals in homoribofuranose derivatives. Tetrahedron 55:18, pages 5705-5718.
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Stuart Licht & Joanne Stubbe. 1999. Comprehensive Natural Products Chemistry. Comprehensive Natural Products Chemistry 163 203 .
Junior Wolf, Claude Monneret, Renée Pontikis & Jean-Claude Florent. (1998) New Synthetic Routes for the Preparation of 2′-C-Methylene Nucleosides. European Journal of Organic Chemistry 1998:11, pages 2417-2423.
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Marc Fontecave, Michel Lepoivre, Eric Elleingand, Catherine Gerez & Olivier Guittet. (1998) Resveratrol, a remarkable inhibitor of ribonucleotide reductase. FEBS Letters 421:3, pages 277-279.
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Pierre M.J Jung, Jérôme Dauvergne, Alain Burger & Jean-François Biellmann. (1997) Cyclization by free radical addition of stannyl or thiyl radical to 3′-β-ethynyl uridine. Is the 3′-β-ethynyl group a spin trap in ribonucleotide reductase?. Tetrahedron Letters 38:33, pages 5877-5880.
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Stefano Manfredini, Pier Giovanni Baraldi, Rita Bazzanini, Daniele Simoni, Jan Balzarini & Erik De Clercq. (1997) Synthesis and antiproliferative activity of 2′-O-allyl-1-β-D-arabinofuranosyl-uracil, -cytosine and -adenine. Bioorganic & Medicinal Chemistry Letters 7:4, pages 473-478.
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JoAnne Stubbe & Wilfred A. van der Donk. (1995) Ribonucleotide reductases: radical enzymes with suicidal tendencies. Chemistry & Biology 2:12, pages 793-801.
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