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I. NUCLEOSIDES: Biological Activity

Studies of the Pharmacokinetics and Toxicology of 2′,3′-Dideoxy-β-L-5-fluorocytidine (β-L-FddC) and 2′,3′-Dideoxy-β-L-cytidine (β-L-ddC) In Vivo; and Synthesis and Antiviral Evaluations of 2′,3′-Dideoxy-β-L-5-azacytidine

Tai-Shun Lin Department of Pharmacology and The Comprehensive Cancer Center

Xin Guo Department of Pharmacology and The Comprehensive Cancer Center

Mei-Zhen Luo Department of Pharmacology and The Comprehensive Cancer Center

Mao-Chin Liu Department of Pharmacology and The Comprehensive Cancer Center

Yong-Lian Zhu Department of Pharmacology and The Comprehensive Cancer Center

Ginger E. Dutschman Department of Pharmacology and The Comprehensive Cancer Center

S. Balakrishna Pai Department of Pharmacology and The Comprehensive Cancer Center

Mao-Mi Li Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, 06520-8066, U.S.A.

Yung-Chi Cheng Department of Pharmacology and The Comprehensive Cancer Center

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G. Gosselin, V. Boudou, J.-F. Griffon, G. Pavia, C. Pierra, J.-L. Imbach, A.-M. Aubertin, R.F. Schinazi, A. Faraj & J.-P. Sommadossi. (1997) New Unnatural L-Nucleoside Enantiomers:From Their Stereospecific Synthesis to Their Biological Activities. Nucleosides and Nucleotides 16:7-9, pages 1389-1398.
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Tai-Shun Lin, Mei-Zhen Luo, Ju-Liang Zhu, Mao-Chin Liu, Yong-Lian Zhu, GingerE. Dutschman & Yung-Chi Cheng. (1995) Synthesis of a Series of Purine 2′,3′-Dideoxy-L-Nucleoside Analogues as Potential Antiviral Agents. Nucleosides and Nucleotides 14:8, pages 1759-1783.
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Jean-François Griffon, Christophe Mathé, Abdesslem Faraj, Anne-Marie Aubertin, Erik De Clercq, Jan Balzarini, Jean-Pierre Sommadossi & Gilles Gosselin. (2001) Stereospecific synthesis and biological evaluations of β-l-pentofuranonucleoside derivatives of 5-fluorouracil and 5-fluorocytosine. European Journal of Medicinal Chemistry 36:5, pages 447-460.
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D Salvatori, S Vincenzetti, G Maury, G Gosselin, G Gaubert & A Vita. (2001) Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs. Comparative Immunology, Microbiology and Infectious Diseases 24:2, pages 113-122.
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Gilles Gaubert, Christophe Mathé, Jean-Louis Imbach, Staffan Eriksson, Silvia Vincenzetti, Daniela Salvatori, Alberto Vita & Georges Maury. (2000) Unnatural enantiomers of 5-azacytidine analogues: Syntheses and enzymatic properties. European Journal of Medicinal Chemistry 35:11, pages 1011-1019.
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L. A. Agrofoglio & S. R. ChallandL. A. Agrofoglio & S. R. Challand. 1998. Acyclic, Carbocyclic and L-Nucleosides. Acyclic, Carbocyclic and L-Nucleosides 285 322 .

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Studies of the Pharmacokinetics and Toxicology of 2′,3′-Dideoxy-β-L-5-fluorocytidine (β-L-FddC) and 2′,3′-Dideoxy-β-L-cytidine (β-L-ddC) In Vivo; and Synthesis and Antiviral Evaluations of 2′,3′-Dideoxy-β-L-5-azacytidine

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Studies of the Pharmacokinetics and Toxicology of 2′,3′-Dideoxy-β-L-5-fluorocytidine (β-L-FddC) and 2′,3′-Dideoxy-β-L-cytidine (β-L-ddC) In Vivo; and Synthesis and Antiviral Evaluations of 2′,3′-Dideoxy-β-L-5-azacytidine

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