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Nucleosides and Nucleotides Volume 14, 1995 - Issue 3-5
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III. OLIGONUCLEOTIDES: Chemistry

Synthesis of Protected 3′,5′-Di-2′-Deoxythymidine-(α-hydroxy-2-nitrobenzyl)-phosphonate Diesters as Dimer Building Blocks for Oligonucleotides

Chris Meier Institute of Organic Chemistry, University of Frankfurt, Marie-Curie-Str. 11, D-60439, Frankfurt/Main, Germany
&
Ralf Mauritz Institute of Organic Chemistry, University of Frankfurt, Marie-Curie-Str. 11, D-60439, Frankfurt/Main, Germany
Pages 803-804 | Published online: 16 Feb 2007

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Read on this site (2)

W. Fendrich & C. Meier. (2003) Determination of the Absolute P-Configuration of a Phthalidyl-Phosphonate Thymidine-Thymidine Dimer. Nucleosides, Nucleotides & Nucleic Acids 22:5-8, pages 1127-1129.
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RalfP. Mauritz, Chris Meier & Eugen Uhlmann. (1997) Synthesis of 3′,5′-Dithymidylyl-α-hydroxyphosphonate Dimer Building Blocks for Oligonucleotide Synthesis—A New Pro-oliguncleotide. Nucleosides and Nucleotides 16:7-9, pages 1209-1212.
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Articles from other publishers (8)

Christian Ducho. (2015) Enzymatically Cleavable siRNA Prodrugs: a New Paradigm for the Intracellular Delivery of RNA-Based Therapeutics. ChemMedChem 10:10, pages 1625-1627.
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Sally Freeman & Kenneth C. Ross. 1997. 111 147 .
Chris Meier. (2003) 2‐Nucleos‐5′‐ O ‐yl‐4 H ‐1,3,2‐benzodioxaphos‐phinin‐2‐oxides—A New Concept for Lipophilic, Potential Prodrugs of Biologically Active Nucleoside Monophosphates . Angewandte Chemie International Edition in English 35:1, pages 70-72.
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Chris Meier. (2006) 2‐Nucleos‐5′‐ O ‐yl‐4 H ‐1,3,2‐benzodioxaphosphinin‐2‐oxide—ein neues Konzept für lipophile, potentielle Prodrugs biologisch' aktiver Nucleosidmonophosphate . Angewandte Chemie 108:1, pages 77-79.
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Chris Meier & Wolfgang H.G. Laux. (1996) Asymmetric synthesis of chiral, Nonracemic dialkyl-α-hydroxyalkylphosphonates via a (−)-Chlorodiiso-pinocampheylborane (Ipc2B-Cl) reduction. Tetrahedron: Asymmetry 7:1, pages 89-94.
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Chris Meier & Wolfgang H.G. Laux. (1996) Enantioselective synthesis of diisopropyl α-, β-, and γ-hydroxyarylalkylphosphonates from ketophosphonates: A study on the effect of the phosphonyl group. Tetrahedron 52:2, pages 589-598.
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Chris Meier, Lothar W. Habel, Jan Balzarini & Eric De Clercq. (2006) Lipophilic α‐hydroxybenzylphosphonates as prodrugs of 3′‐azido‐2′,3′‐dideoxythymidine (AZT). Liebigs Annalen 1995:12, pages 2195-2202.
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Chris Meier, Wolfgang H. G. Laux & Jan W. Bats. (2006) Asymmetric synthesis of chiral, nonracemic dialkyl α‐hydroxyarylmethyl‐and α‐, β‐ and γ‐hydroxyalkylphosphonates from keto phosphonates. Liebigs Annalen 1995:11, pages 1963-1979.
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