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Target Article

A Framework for Unrestricted Prenatal Whole-Genome Sequencing: Respecting and Enhancing the Autonomy of Prospective Parents

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Read on this site (19)

Rosamond Rhodes & Matthew J. Drago. (2023) Prenatal Testing: Responsibility and Reality. The American Journal of Bioethics 23:5, pages 128-131.
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Kelsey Mumford, Nina Roesner & Benjamin E. Berkman. (2023) The Potential Role of Nudging in Expanded Noninvasive Prenatal Testing. The American Journal of Bioethics 23:3, pages 61-63.
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David Wasserman. (2023) Noninvasive Testing for “Non-Medical” Traits: A Misplaced Expressive Concern, Tough Policy Choices. The American Journal of Bioethics 23:3, pages 59-61.
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Angus Clarke. (2023) Terminology and Consistency. The American Journal of Bioethics 23:3, pages 53-55.
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Hilary Bowman-Smart, Christopher Gyngell, Cara Mand, David J. Amor, Martin B. Delatycki & Julian Savulescu. (2023) Non-Invasive Prenatal Testing for “Non-Medical” Traits: Ensuring Consistency in Ethical Decision-Making. The American Journal of Bioethics 23:3, pages 3-20.
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Katharine Press Callahan & Chris Feudtner. (2022) Genetic Testing Is Messier in Practice than in Theory: Lessons from Neonatology. The American Journal of Bioethics 22:2, pages 37-39.
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Michelle J. Bayefsky & Benjamin E. Berkman. (2022) Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?. The American Journal of Bioethics 22:2, pages 4-22.
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Benjamin S. Wilfond. (2017) Breaking the Sounds of Silence: Respecting People With Disabilities and Reproductive Decision Making. The American Journal of Bioethics 17:1, pages 37-39.
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Rosamond Rhodes. (2017) Resisting Paternalism in Prenatal Whole-Genome Sequencing. The American Journal of Bioethics 17:1, pages 35-37.
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Jeffrey R. Botkin, Leslie P. Francis & Nancy C. Rose. (2017) Concerns About Justification for Fetal Genome Sequencing. The American Journal of Bioethics 17:1, pages 23-25.
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Megan Allyse, James P. Evans & Marsha Michie. (2017) Dr. Pangloss's Clinic: Prenatal Whole Genome Sequencing and a Return to Reality. The American Journal of Bioethics 17:1, pages 21-23.
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Christian Munthe. (2017) Permissibility or Priority? Testing or Screening? Essential Distinctions in the Ethics of Prenatal Testing. The American Journal of Bioethics 17:1, pages 30-32.
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W. Kevin Conley II, Douglas C. McAdams, G. Kevin Donovan & Kevin T. FitzGerald. (2017) Beneficence In Utero: A Framework for Restricted Prenatal Whole-Genome Sequencing to Respect and Enhance the Well-Being of Children. The American Journal of Bioethics 17:1, pages 28-29.
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Jessica Mozersky & Pamela Sankar. (2017) Mandating Moral Reflection?. The American Journal of Bioethics 17:1, pages 32-34.
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Benjamin E. Berkman & Michelle Bayefsky. (2017) Prenatal Whole Genome Sequencing: An Argument for Professional Self-Regulation. The American Journal of Bioethics 17:1, pages 26-28.
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Vardit Ravitsky, Francois Rousseau & Anne-Marie Laberge. (2017) Providing Unrestricted Access to Prenatal Testing Does Not Translate to Enhanced Autonomy. The American Journal of Bioethics 17:1, pages 39-41.
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Chris Kaposy. (2017) Noninvasive Prenatal Whole-Genome Sequencing: A Solution in Search of a Problem. The American Journal of Bioethics 17:1, pages 42-44.
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Zoë Claesen, Neeltje Crombag, Lidewij Henneman, Joris Robert Vermeesch & Pascal Borry. (2023) Expanded Non-invasive Prenatal Testing (NIPT). Journal of Bioethical Inquiry 20:1, pages 41-49.
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Fermín Jesús González-Melado. 2023. Clinical Ethics At the Crossroads of Genetic and Reproductive Technologies. Clinical Ethics At the Crossroads of Genetic and Reproductive Technologies 275 304 .
Margot Kelly-Hedrick, Gail Geller, Angie C. Jelin & Marielle S. Gross. (2022) Perceived Value of Prenatal Ultrasound Screening: A Survey of Pregnant Women. Maternal and Child Health Journal 27:1, pages 101-110.
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Hazar Haidar, Stanislav Birko, Anne-Marie Laberge, Jessica Le Clerc-Blain & Vardit Ravitsky. (2022) Views of Canadian healthcare professionals on the future uses of non-invasive prenatal testing: a mixed method study. European Journal of Human Genetics 30:11, pages 1269-1275.
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Todd Lencz, Maya Sabatello, Anna Docherty, Roseann E Peterson, Takahiro Soda, Jehannine Austin, Laura Bierut, David Crepaz-Keay, David Curtis, Franziska Degenhardt, Laura Huckins, Gabriel Lazaro-Munoz, Manuel Mattheisen, Bettina Meiser, Holly Peay, Marcella Rietschel, Consuelo Walss-Bass & Lea K Davis. (2022) Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits. The Lancet Psychiatry 9:10, pages 838-844.
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Esther Braun. (2022) An autonomy-based approach to assisted suicide: a way to avoid the expressivist objection against assisted dying laws. Journal of Medical Ethics, pages medethics-2022-108375.
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Charles Dupras, Stanislav Birko, Aliya O. Affdal, Hazar Haidar, Marie-Eve Lemoine & Vardit Ravitsky. (2022) Governing the futures of non-invasive prenatal testing: An exploration of social acceptability using the Delphi method. Social Science & Medicine 304, pages 112930.
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Tamar Nov-Klaiman, Marina Frisman, Aviad E. Raz & Christoph Rehmann-Sutter. (2022) Views on disability and prenatal testing among families with Down syndrome and disability activists: A comparative analysis of interviews from Germany and Israel. Social Science & Medicine 303, pages 115021.
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Dorit Barlevy, David Wasserman & Adrienne Asch. 2013. The International Encyclopedia of Ethics. The International Encyclopedia of Ethics 1 18 .
Dagmar Schmitz & Wolfram Henn. (2021) The fetus in the age of the genome. Human Genetics 141:5, pages 1017-1026.
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Hazar Haidar & Renata Iskander. (2022) Non-invasive Prenatal Testing for Fetal Whole Genome Sequencing: An Interpretive Critical Review of the Ethical, Legal, Social, and Policy Implications. Canadian Journal of Bioethics 5:1, pages 1.
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David Wasserman. 2022. Born Well: Prenatal Genetics and the Future of Having Children. Born Well: Prenatal Genetics and the Future of Having Children 125 136 .
Stephanie A Kraft, Erin Rothwell, Seema K Shah, Devan M Duenas, Hannah Lewis, Kristin Muessig, Douglas J Opel, Katrina A B Goddard & Benjamin S Wilfond. (2021) Demonstrating ‘respect for persons’ in clinical research: findings from qualitative interviews with diverse genomics research participants. Journal of Medical Ethics 47:12, pages e8-e8.
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Alberto Asquer & Inna Krachkovskaya. (2021) A Bibliometric Analysis of Research on CRISPR in Social Sciences and Humanities. Re:GEN Open 1:1, pages 14-23.
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Mohammed I Khan, Matthew Holek, Faris Bdair, Lawrence Mbuagbaw, Sandra M Eldridge, Claire L Chan, Michael J Campbell, Christine M Bond, Sally Hopewell, Gillian A Lancaster & Lehana Thabane. (2020) Assessing the transparency of informed consent in feasibility and pilot studies: a single-centre quality assurance study protocol. BMJ Open 10:6, pages e036226.
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Alison M. Elliott. (2020) Genetic Counseling and Genome Sequencing in Pediatric Rare Disease. Cold Spring Harbor Perspectives in Medicine 10:3, pages a036632.
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Ruth M. Farrell, Patricia K. Agatisa, Marsha M. Michie, Amy Greene & Paul J. Ford. (2019) The personal utility of cfDNA screening: Pregnant patients' experiences with cfDNA screening and views on expanded cfDNA panels. Journal of Genetic Counseling 29:1, pages 88-96.
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Greg Stapleton, Wybo Dondorp, Peter Schröder-Bäck & Guido de Wert. (2019) Just choice: a Danielsian analysis of the aims and scope of prenatal screening for fetal abnormalities. Medicine, Health Care and Philosophy 22:4, pages 545-555.
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Johannes Reinders, Tim Stainton & Trevor R. Parmenter. (2019) The Quiet Progress of the New Eugenics. Ending the Lives of Persons With Intellectual and Developmental Disabilities for Reasons of Presumed Poor Quality of Life. Journal of Policy and Practice in Intellectual Disabilities 16:2, pages 99-112.
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Bobbi Fleiss, Flora Wong, Fiona Brownfoot, Isabelle K. Shearer, Olivier Baud, David W. Walker, Pierre Gressens & Mary Tolcos. (2019) Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury. Frontiers in Endocrinology 10.
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Shelin Adam, Patricia H. Birch, Rachel R. Coe, Nick Bansback, Adrian L. Jones, Mary B. Connolly, Michelle K. Demos, Eric B. Toyota, Matthew J. Farrer & Jan M. Friedman. (2018) Assessing an Interactive Online Tool to Support Parents' Genomic Testing Decisions. Journal of Genetic Counseling 28:1, pages 10-17.
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Sam Riedijk, Karin Diderich, Robert-Jan Galjaard & Gosia Srebniak. 2019. Clinical Genome Sequencing. Clinical Genome Sequencing 157 180 .
Angus J. Clarke & Carina Wallgren-Pettersson. (2018) Ethics in genetic counselling. Journal of Community Genetics 10:1, pages 3-33.
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Guido M. W. R. de Wert & Wybo J. Dondorp. 2019. Textbook of Obstetrics and Gynaecology. Textbook of Obstetrics and Gynaecology 27 50 .
Sarah Harris, Kelly Gilmore, Emily Hardisty, Anne Drapkin Lyerly & Neeta L. Vora. (2018) Ethical and counseling challenges in prenatal exome sequencing. Prenatal Diagnosis 38:12, pages 897-903.
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Carlo V Bellieni. (2018) Consumerism: a threat to health?. Journal of the Royal Society of Medicine 111:4, pages 112-112.
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Ruth M. Farrell & Megan A. Allyse. (2018) Key Ethical Issues in Prenatal Genetics. Obstetrics and Gynecology Clinics of North America 45:1, pages 127-141.
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Stephanie A. Kraft, Carmit K. McMullen, Kathryn M. Porter, Tia L. Kauffman, James V. Davis, Jennifer L. Schneider, Katrina A. B. Goddard & Benjamin S. Wilfond. (2017) Patient perspectives on the use of categories of conditions for decision making about genomic carrier screening results. American Journal of Medical Genetics Part A 176:2, pages 376-385.
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M.C. de Wit, E.M. Bunnik, A.T.J.I. Go, I.D. de Beaufort, R.M.W. Hofstra, E.A.P. Steegers & R.J.H. Galjaard. (2017) Amniocentesis is still the best option for advanced genomic testing in case of fetal malformations. Prenatal Diagnosis 37:13, pages 1360-1363.
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Vardit Ravitsky. (2017) The Shifting Landscape of Prenatal Testing: Between Reproductive Autonomy and Public Health . Hastings Center Report 47, pages S34-S40.
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Ketil Slagstad & Bjørn Hofmann. (2017) Ny fostertest ble svaret, men hva var spørsmålet?. Nytt Norsk Tidsskrift 34:2, pages 150-164.
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Bjørn Hofmann & Ketil Slagstad. (2017) Fostertest som prøvestein og brekkstang. Tidsskrift for Den norske legeforening 137:6, pages 435-436.
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