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TARGET ARTICLE

Human Brain Surrogates Research: The Onrushing Ethical Dilemma

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Read on this site (12)

Heather Browning & Walter Veit. (2023) Regulating Possibly Sentient Human Cerebral Organoids. AJOB Neuroscience 14:2, pages 197-199.
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Federico Zilio & Andrea Lavazza. (2023) Consciousness in a Rotor? Science and Ethics of Potentially Conscious Human Cerebral Organoids. AJOB Neuroscience 14:2, pages 178-196.
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Jeantine E. Lunshof. (2021) Brain Surrogates—Empty or Full Makes the Difference. The American Journal of Bioethics 21:1, pages 46-48.
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Rachel A. Ankeny & Ernst Wolvetang. (2021) Testing the Correlates of Consciousness in Brain Organoids: How Do We Know and What Do We Do?. The American Journal of Bioethics 21:1, pages 51-53.
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Tomasz Żuradzki. (2021) Against the Precautionary Approach to Moral Status: The Case of Surrogates for Living Human Brains. The American Journal of Bioethics 21:1, pages 53-56.
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Monika Piotrowska. (2021) Human Brain Surrogates: Models or Distortions?. The American Journal of Bioethics 21:1, pages 66-68.
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Arun Sharma, Peter Zuk & Christopher Thomas Scott. (2021) Scientific and Ethical Uncertainties in Brain Organoid Research. The American Journal of Bioethics 21:1, pages 48-51.
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Suzanne Metselaar, Jeroen Geurts & Gerben Meynen. (2021) Responding to Human Brain Surrogates Research: The Value of Empirical Ethics. The American Journal of Bioethics 21:1, pages 64-66.
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Julian J. Koplin. (2021) The Moral Relevance of Humanization. The American Journal of Bioethics 21:1, pages 59-61.
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Jonathan Birch & Heather Browning. (2021) Neural Organoids and the Precautionary Principle. The American Journal of Bioethics 21:1, pages 56-58.
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Benjamin Capps. (2021) Philosophy is Still Missing from the Human-Mouse Chimera Debate. The American Journal of Bioethics 21:1, pages 61-63.
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Articles from other publishers (39)

J. Lomax Boyd & Nethanel Lipshitz. (2023) Dimensions of Consciousness and the Moral Status of Brain Organoids. Neuroethics 17:1.
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Sarah Diner. (2023) Potential Consciousness of Human Cerebral Organoids: on Similarity-Based Views in Precautionary Discourse. Neuroethics 16:3.
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Masanori Kataoka, Christopher Gyngell, Julian Savulescu & Tsutomu Sawai. (2023) The Ethics of Human Brain Organoid Transplantation in Animals. Neuroethics 16:3.
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Anja Pichl, Robert Ranisch, Ozan Altan Altinok, Melpomeni Antonakaki, Andrew J. Barnhart, Katherine Bassil, J. Lomax Boyd, Alice Andrea Chinaia, Sarah Diner, Maxence Gaillard, Henry T. Greely, Joshua Jowitt, Karola Kreitmair, David Lawrence, Tim Nicholas Lee, Alex McKeown, Vorathep Sachdev, Silke Schicktanz, Jeremy Sugarman, Katharina Trettenbach, Lara Wiese, Hannes Wolff & Garðar Árnason. (2023) Ethical, legal and social aspects of human cerebral organoids and their governance in Germany, the United Kingdom and the United States. Frontiers in Cell and Developmental Biology 11.
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Brett J. Kagan, Christopher Gyngell, Tamra Lysaght, Victor M. Cole, Tsutomu Sawai & Julian Savulescu. (2023) The technology, opportunities, and challenges of Synthetic Biological Intelligence. Biotechnology Advances 68, pages 108233.
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Shyam R. Sihare. (2023) Potential of quantum computing to effectively comprehend the complexity of brain. Applied Intelligence 53:22, pages 27459-27482.
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Katherine E. MacDuffie, Jason L. Stein, Dan Doherty, Suman Jayadev, Jessica B. Girault, Katherine A. Emmons, Madison Rose Glass, Jennifer C. Dempsey, Natasha Marrus, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Joseph Piven & Benjamin S. Wilfond. (2023) Donor perspectives on informed consent and use of biospecimens for brain organoid research. Stem Cell Reports 18:7, pages 1389-1393.
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Andrea Lavazza & Massimo Reichlin. (2023) Human Brain Organoids: Why There Can Be Moral Concerns If They Grow Up in the Lab and Are Transplanted or Destroyed. Cambridge Quarterly of Healthcare Ethics, pages 1-15.
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Valerie A. Tornini, Santiago Peregalli Politi, Lori Bruce & Stephen R. Latham. (2023) Maximizing biomedical research impacts through bioethical considerations. Disease Models & Mechanisms 16:4.
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Karola Kreitmair. (2023) Consciousness and the Ethics of Human Brain Organoid Research. Cambridge Quarterly of Healthcare Ethics, pages 1-11.
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Joel Frohlich, Tim Bayne, Julia S. Crone, Alessandra DallaVecchia, Asger Kirkeby-Hinrup, Pedro A.M. Mediano, Julia Moser, Karolina Talar, Alireza Gharabaghi & Hubert Preissl. (2023) Not with a “zap” but with a “beep”: measuring the origins of perinatal experience. NeuroImage, pages 120057.
Crossref
Lena Smirnova, Brian S. Caffo, David H. Gracias, Qi Huang, Itzy E. Morales Pantoja, Bohao Tang, Donald J. Zack, Cynthia A. Berlinicke, J. Lomax Boyd, Timothy D. Harris, Erik C. Johnson, Brett J. Kagan, Jeffrey Kahn, Alysson R. Muotri, Barton L. Paulhamus, Jens C. Schwamborn, Jesse Plotkin, Alexander S. Szalay, Joshua T. Vogelstein, Paul F. Worley & Thomas Hartung. (2023) Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish. Frontiers in Science 1.
Crossref
Eliza Goddard, Eva Tomaskovic-Crook, Jeremy Micah Crook & Susan Dodds. (2023) Human Brain Organoids and Consciousness: Moral Claims and Epistemic Uncertainty. Organoids 2:1, pages 50-65.
Crossref
J. Lomax Boyd. (2023) Scientific and ethical challenges of brain chimeras converge on an ‘enriched’ approach. Molecular Psychology: Brain, Behavior, and Society 2, pages 16.
Crossref
Sietske A.L. van Till, Mariia V. Maksimova, Ghislaine J.M.W. van Thiel & Eline M. Bunnik. (2023) An assessment of the moral value of neuronal cell models and brain organoids. Molecular Psychology: Brain, Behavior, and Society 2, pages 15.
Crossref
Jonathan Birch. (2023) When is a brain organoid a sentience candidate?. Molecular Psychology: Brain, Behavior, and Society 2, pages 22.
Crossref
Heather Browning & Walter Veit. (2023) The welfare of brain organoids. Molecular Psychology: Brain, Behavior, and Society 2, pages 4.
Crossref
Alexander R Harris, Patrick McGivern & Frederic Gilbert. (2023) A review of ethical and regulatory issues in the clinical application of stem cell-derived tissue constructs. Molecular Psychology: Brain, Behavior, and Society 2, pages 8.
Crossref
Andrea Lavazza & Alice Andrea Chinaia. 2023. Clinical Ethics At the Crossroads of Genetic and Reproductive Technologies. Clinical Ethics At the Crossroads of Genetic and Reproductive Technologies 431 453 .
Iris Coates McCall & Veljko Dubljević. 2023. Neurobiology of Brain Disorders. Neurobiology of Brain Disorders 1025 1045 .
Julian Koplin & Neera Bhatia. 2023. Handbook of Bioethical Decisions. Volume I. Handbook of Bioethical Decisions. Volume I 607 623 .
Alexander R. Harris, Mary Jean Walker & Frederic Gilbert. (2022) Ethical and regulatory issues of stem cell-derived 3-dimensional organoid and tissue therapy for personalised regenerative medicine. BMC Medicine 20:1.
Crossref
Dide de Jongh, Emma K. Massey, Ekaterine Berishvili, Laura Mar Fonseca, Fanny Lebreton, Kevin Bellofatto, Juliette Bignard, Jochen Seissler, Leila Wolf-van Buerck, Mohsen Honarpisheh, Yichen Zhang, Yutian Lei, Monika Pehl, Antonia Follenzi, Christina Olgasi, Alessia Cucci, Chiara Borsotti, Simone Assanelli, Lorenzo Piemonti, Antonio Citro, Silvia Pellegrini, Cataldo Pignatelli, Francesco Campo, Olivier Thaunat, Antonia J. Cronin, Devi Mey, Chiara Parisotto, Giovanna Rossi, Patrick Kugelmeier, Petra Wolint, Markus Mühlemann, Karolina Pal-Kutas, Marco Cavallaro, Julia Götz, Jeanette Müller & Eline M. Bunnik. (2022) Organoids: a systematic review of ethical issues. Stem Cell Research & Therapy 13:1.
Crossref
Mary G. Garry, Arthur L. Caplan & Daniel J. Garry. (2022) Emerging technologies and ethics—exogenic chimeric humanized organs. American Journal of Transplantation 22:12, pages 2786-2790.
Crossref
Bartlomiej Chomanski. (2022) Sims and Vulnerability: On the Ethics of Creating Emulated Minds. Science and Engineering Ethics 28:6.
Crossref
Andie Massey, Matthew Boag, Annie Magnier, Dharah Bispo, Tien Khoo & Dean Pountney. (2022) Glymphatic System Dysfunction and Sleep Disturbance May Contribute to the Pathogenesis and Progression of Parkinson’s Disease. International Journal of Molecular Sciences 23:21, pages 12928.
Crossref
Eisuke Nakazawa, Tamami Fukushi, Koji Tachibana, Ryo Uehara, Fumie Arie, Nargis Akter, Megumi Maruyama, Kentaro Morita, Toshiyuki Araki & Norihiro Sadato. (2022) The way forward for neuroethics in Japan: A review of five topics surrounding present challenges. Neuroscience Research 183, pages 7-16.
Crossref
Andrew J. Barnhart & Kris Dierickx. (2022) The Many Moral Matters of Organoid Models: A systematic review of reasons. Medicine, Health Care and Philosophy 25:3, pages 545-560.
Crossref
Lulu Ding, Zhenyu Xiao, Xia Gong & Yaojin Peng. (2022) Knowledge graphs of ethical concerns of cerebral organoids. Cell Proliferation 55:8.
Crossref
Larry Carbone. 2022. Ethics in Veterinary Practice. Ethics in Veterinary Practice 227 248 .
Takuya Niikawa, Yoshiyuki Hayashi, Joshua Shepherd & Tsutomu Sawai. (2022) Human Brain Organoids and Consciousness. Neuroethics 15:1.
Crossref
Turhan Canli. (2022) 25 Years of Molecular Psychology: The best is yet to come. Molecular Psychology: Brain, Behavior, and Society 1, pages 1.
Crossref
Linda F. Hogle. 2022. The Palgrave Handbook of the Anthropology of Technology. The Palgrave Handbook of the Anthropology of Technology 547 568 .
Andrea Lavazza. 2022. Brain Organoids in Research and Therapy. Brain Organoids in Research and Therapy 65 95 .
Luís Cordeiro-Rodrigues & Cornelius Ewuoso. (2021) An Afro-Communitarian Relational Approach to Brain Surrogates Research. Neuroethics 14:3, pages 561-574.
Crossref
Andrea Lavazza. (2021) ‘Consciousnessoids’: clues and insights from human cerebral organoids for the study of consciousness. Neuroscience of Consciousness 2021:2.
Crossref
Julien G. Roth, Michelle S. Huang, Thomas L. Li, Vivian R. Feig, Yuanwen Jiang, Bianxiao Cui, Henry T. Greely, Zhenan Bao, Sergiu P. Paşca & Sarah C. Heilshorn. (2021) Advancing models of neural development with biomaterials. Nature Reviews Neuroscience 22:10, pages 593-615.
Crossref
Insoo Hyun, Ellen Wright Clayton, Yali Cong, Misao Fujita, Steven A. Goldman, Lori R. Hill, Nuria Monserrat, Hiromitsu Nakauchi, Roger A. Pedersen, Heather M. Rooke, Jun Takahashi & Jürgen A. Knoblich. (2021) ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports 16:6, pages 1409-1415.
Crossref
Henry T. Greely & Nita A. Farahany. (2021) Advancing the ethical dialogue about monkey/human chimeric embryos. Cell 184:8, pages 1962-1963.
Crossref

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