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Original Articles

Gene Expression Patterns in Estrogen (Nonylphenol) and Aryl Hydrocarbon Receptor Agonists (PCB-77) Interaction Using Rainbow Trout (Oncorhynchus Mykiss) Primary Hepatocyte Culture

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Pages 1-19 | Published online: 24 Feb 2007

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Read on this site (3)

Carla Quintaneiro, Amadeu M. V. M. Soares, Diana Costa & Marta S. Monteiro. (2019) Effects of PCB-77 in adult zebrafish after exposure during early life stages. Journal of Environmental Science and Health, Part A 54:5, pages 478-483.
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Maria T. Hultman, Karina Petersen & Knut Erik Tollefsen. (2017) Characterizing combined effects of antiestrogenic chemicals on vitellogenin production in rainbow trout (Oncorhynchus mykiss) hepatocytes. Journal of Toxicology and Environmental Health, Part A 80:16-18, pages 987-1001.
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Jan L. Lyche, Rasoul Nourizadeh-Lillabadi, Camilla Almaas, Benedicte Stavik, Vidar Berg, Janneche Utne Skåre, Peter Alestrøm & Erik Ropstad. (2010) Natural Mixtures of Persistent Organic Pollutants (POP) Increase Weight Gain, Advance Puberty, and Induce Changes in Gene Expression Associated with Steroid Hormones and Obesity in Female Zebrafish. Journal of Toxicology and Environmental Health, Part A 73:15, pages 1032-1057.
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Articles from other publishers (40)

Xin Kang, Dongpeng Li, Xiaoxiang Zhao, Yanfeng Lv, Xi Chen, Xinshan Song, Xiangyu Liu, Chengrong Chen & Xin Cao. (2022) Long-Term Exposure to Phenanthrene Induced Gene Expressions and Enzyme Activities of Cyprinus carpio below the Safe Concentration. International Journal of Environmental Research and Public Health 19:4, pages 2129.
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Burak Kaptaner, Can Yılmaz, Handan Aykut, Emine Doğan, Ceylan Fidan, Müşerref Bostancı & Fatoş Yıldız. (2021) Bisphenol S leads to cytotoxicity-induced antioxidant responses and oxidative stress in isolated rainbow trout (Oncorhyncus mykiss) hepatocytes. Molecular Biology Reports 48:12, pages 7657-7666.
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Zhang Longfei, Wang Mengyuan, Wu Di, Cai Youqiong & Shi Yongfu. (2021) The effects of PBB153 on the levels of E2, T and Vtg in zebrafish. IOP Conference Series: Earth and Environmental Science 792:1, pages 012047.
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Handan Aykut & Burak Kaptaner. (2021) In vitro effects of bisphenol F on antioxidant system indicators in the isolated hepatocytes of rainbow trout (Oncorhyncus mykiss). Molecular Biology Reports 48:3, pages 2591-2599.
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You-ning Ma, Li-hua Sun, Shu-ying Li, Yan-xia Ni, Zhao-yun Cao, Ming-xue Chen & Ren-xiang Mou. (2020) Modulation of steroid metabolism and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to triadimefon. Environmental Pollution 262, pages 114145.
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Haigang Chen, Zhe Zhang, Linbao Zhang, Fei Tian, Zhenzhao Tang, Wengui Cai & Xiaoping Jia. (2020) Effects of di-n-butyl phthalate on gills- and liver-specific EROD activities and CYP1A levels in juvenile red snapper (Lutjanus argentimaculatus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 232, pages 108757.
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Elvira Mennillo, Aina O. Adeogun & Augustine Arukwe. (2020) Quality screening of the Lagos lagoon sediment by assessing the cytotoxicity and toxicological responses of rat hepatoma H4IIE and fish PLHC-1 cell-lines using different extraction approaches. Environmental Research 182, pages 108986.
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Elvira Mennillo, Francesca Cappelli & Augustine Arukwe. (2019) Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to organophosphate esters (OPEs). Toxicology and Applied Pharmacology 371, pages 84-94.
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Md Saydur Rahman & Peter Thomas. (2018) Interactive effects of hypoxia and PCB co-exposure on expression of CYP1A and its potential regulators in Atlantic croaker liver. Environmental Toxicology 33:4, pages 411-421.
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Morgan Lizabeth Bender, Marianne Frantzen, Ireen Vieweg, Inger-Britt Falk-Petersen, Helge Kreutzer Johnsen, Geir Rudolfsen, Knut Erik Tollefsen, Paul Dubourg & Jasmine Nahrgang. (2016) Effects of chronic dietary petroleum exposure on reproductive development in polar cod (Boreogadus saida). Aquatic Toxicology 180, pages 196-208.
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Burak Kaptaner. (2015) Cytotoxic effects of 4-octylphenol on fish hepatocytes. Cytotechnology 68:4, pages 1577-1583.
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Maria T. Hultman, You Song & Knut Erik Tollefsen. (2015) 17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquatic Toxicology 169, pages 90-104.
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Preeyaporn Koedrith, Hye Lim Kim & Young Rok Seo. (2015) Integrative toxicogenomics-based approach to risk assessment of heavy metal mixtures/complexes: strategies and challenges. Molecular & Cellular Toxicology 11:3, pages 265-276.
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Hizlan H. Agus, Sibel Sümer & Figen Erkoç. (2015) Toxicity and molecular effects of di-n-butyl phthalate (DBP) on CYP1A, SOD, and GPx in Cyprinus carpio (common carp). Environmental Monitoring and Assessment 187:7.
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Jacqueline Ferris, Mao Li, John F. Leatherland & W. Allan King. (2014) Estrogen and glucocorticoid receptor agonists and antagonists in oocytes modulate the pattern of expression of genes that encode nuclear receptor proteins in very early stage rainbow trout (Oncorhynchus mykiss) embryos. Fish Physiology and Biochemistry 41:1, pages 255-265.
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Mirella Vazzana, Gabriele Reas, Matteo Cammarata, Vincenzo Arizza, Vincenzo Ferrantelli & Nicolò Parrinello. (2014) Aroclor 1254 inhibits the chemiluminescence response of peritoneal cavity cells from sharpsnout sea bream (Diplodus puntazzo). Fish & Shellfish Immunology 39:2, pages 498-502.
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Lídia C.A. Dias, Amadeu M.V.M. Soares, Abel L.G. Ferreira, Cátia S. Santos & Marta S. Monteiro. (2014) Biomarkers of endocrine disruption in juveniles and females of the estuarine fish Pomatoschistus microps. Marine Pollution Bulletin 84:1-2, pages 314-321.
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Ziwei Chang, Ming Lu, So-Sun Kim & Jang-Su Park. (2014) Potential role of HSP90 in mediating the interactions between estrogen receptor (ER) and aryl hydrocarbon receptor (AhR) signaling pathways. Toxicology Letters 226:1, pages 6-13.
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Nik Veldhoen, Michael G. Ikonomou, Vicki Rehaume, Cory Dubetz, David A. Patterson & Caren C. Helbing. (2013) Evidence of disruption in estrogen-associated signaling in the liver transcriptome of in-migrating sockeye salmon of British Columbia, Canada. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 157:2, pages 150-161.
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B. Wens, P. De Boever, M. Verbeke, K. Hollanders & G. Schoeters. (2013) Cultured human peripheral blood mononuclear cells alter their gene expression when challenged with endocrine-disrupting chemicals. Toxicology 303, pages 17-24.
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Margherita Calò, Stefania Casella, Michele Panzera, Patrizia Lo Cascio, Daniela Alberghina & Giuseppe Piccione. (2012) Activation of the Ahr signalling pathway by polychlorobiphenyls causes a marked induction of cytochrome P450 only after depletion of vitellogenin in Sparus aurata. Environmental Toxicology and Pharmacology 34:3, pages 735-742.
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Martine H. Gjernes, Daniel Schlenk & Augustine Arukwe. (2012) Estrogen receptor-hijacking by dioxin-like 3,3′4,4′,5-pentachlorobiphenyl (PCB126) in salmon hepatocytes involves both receptor activation and receptor protein stability. Aquatic Toxicology 124-125, pages 197-208.
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Hyokyoung Won, Seonock Woo, Aekyung Lee, Gunsup Lee, Taek-Kyun Lee & Seungshic Yum. (2012) Heterologous microarray hybridization used for differential gene expression profiling in Arochlor 1260-exposed marine medaka. Toxicology and Environmental Health Sciences 4:2, pages 132-138.
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Rolf Altenburger, Stefan Scholz, Mechthild Schmitt-Jansen, Wibke Busch & Beate I. Escher. (2012) Mixture Toxicity Revisited from a Toxicogenomic Perspective. Environmental Science & Technology 46:5, pages 2508-2522.
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M. Calò, D. Alberghina, A. Bitto, E.R. Lauriano & P. Lo Cascio. (2010) Estrogenic followed by anti-estrogenic effects of PCBs exposure in juvenil fish (Spaurus aurata). Food and Chemical Toxicology 48:8-9, pages 2458-2463.
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Seungshic Yum, Seonock Woo, Yoshihiro Kagami, Hong-Seog Park & Jae-Chun Ryu. (2010) Changes in gene expression profile of medaka with acute toxicity of Arochlor 1260, a polychlorinated biphenyl mixture. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 151:1, pages 51-56.
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Anne S. Mortensen & Augustine Arukwe. (2008) Estrogenic effect of dioxin-like aryl hydrocarbon receptor (AhR) agonist (PCB congener 126) in salmon hepatocytes. Marine Environmental Research 66:1, pages 119-120.
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Anne Skjetne Mortensen & Augustine Arukwe. (2008) Activation of estrogen receptor signaling by the dioxin-like aryl hydrocarbon receptor agonist, 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126) in salmon in vitro system. Toxicology and Applied Pharmacology 227:2, pages 313-324.
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Abby D. Benninghoff & David E. Williams. (2008) Identification of a Transcriptional Fingerprint of Estrogen Exposure in Rainbow Trout Liver. Toxicological Sciences 101:1, pages 65-80.
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Anne S Mortensen & Augustine Arukwe. (2007) Interactions Between Estrogen- and Ah-Receptor Signalling Pathways in Primary Culture of Salmon Hepatocytes Exposed to Nonylphenol and 3,3',4,4'-Tetrachlorobiphenyl (Congener 77). Comparative Hepatology 6:1.
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Anne S. Mortensen, Marte Braathen, Morten Sandvik & Augustine Arukwe. (2007) Effects of hydroxy-polychlorinated biphenyl (OH-PCB) congeners on the xenobiotic biotransformation gene expression patterns in primary culture of Atlantic salmon (Salmo salar) hepatocytes. Ecotoxicology and Environmental Safety 68:3, pages 351-360.
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Anne S. Mortensen & Augustine Arukwe. (2007) Effects of 17α-ethynylestradiol on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquatic Toxicology 85:2, pages 113-123.
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Victoria J. Berdikova Bohne, Kristin Hamre & Augustine Arukwe. (2007) Hepatic metabolism, phase I and II biotransformation enzymes in Atlantic salmon (Salmo Salar, L) during a 12 week feeding period with graded levels of the synthetic antioxidant, ethoxyquin. Food and Chemical Toxicology 45:5, pages 733-746.
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Anne Skjetne Mortensen & Augustine Arukwe. (2007) Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 145:3, pages 431-441.
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Irina Pettersson, Augustine Arukwe, Katrin Lundstedt-Enkel, Anne S. Mortensen & Cecilia Berg. (2006) Persistent sex-reversal and oviducal agenesis in adult Xenopus (Silurana) tropicalis frogs following larval exposure to the environmental pollutant ethynylestradiol. Aquatic Toxicology 79:4, pages 356-365.
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Victoria J. Berdikova Bohne, Kristin Hamre & Augustine Arukwe. (2006) Hepatic Biotransformation and Metabolite Profile during a 2-Week Depuration Period in Atlantic Salmon Fed Graded Levels of the Synthetic Antioxidant, Ethoxyquin. Toxicological Sciences 93:1, pages 11-21.
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Anne S. Mortensen & Augustine Arukwe. (2006) Dimethyl sulfoxide is a potent modulator of estrogen receptor isoforms and xenoestrogen biomarker responses in primary culture of salmon hepatocytes. Aquatic Toxicology 79:1, pages 99-103.
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Jung Soo Seo, Young-Mi Lee, Sang-Oun Jung, Il-Chan Kim, Yong-Dal Yoon & Jae-Seong Lee. (2006) Nonylphenol modulates expression of androgen receptor and estrogen receptor genes differently in gender types of the hermaphroditic fish Rivulus marmoratus. Biochemical and Biophysical Research Communications 346:1, pages 213-223.
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Valentina Meucci & Augustine Arukwe. (2006) The environmental estrogen, 4-nonylphenol modulates brain estrogen-receptor- and aromatase (CYP19) isoforms gene expression patterns in Atlantic salmon (Salmo salar). Marine Environmental Research 62, pages S195-S199.
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Valentina Meucci & Augustine Arukwe. (2006) The xenoestrogen 4-nonylphenol modulates hepatic gene expression of pregnane X receptor, aryl hydrocarbon receptor, CYP3A and CYP1A1 in juvenile Atlantic salmon (Salmo salar). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 142:1-2, pages 142-150.
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