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Original Articles

Activation of de Novo Synthetic Pathway of Ceramides is Responsible for the Initiation of Hydrogen Peroxide–induced Apoptosis in HI-60 Cells

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Pages 1310-1318 | Published online: 24 Jul 2007

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Sang Woo Kim, Hae Jong Kim, Young Jin Chun & Mie Young Kim. (2010) Ceramide Produces Apoptosis Through Induction of p27kip1 by Protein Phosphatase 2A-dependent Akt Dephosphorylation in PC-3 Prostate Cancer Cells. Journal of Toxicology and Environmental Health, Part A 73:21-22, pages 1465-1476.
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Articles from other publishers (10)

Taddesse Yayeh, Ha Ram Jeong, Yoon Soo Park, Sohyeon Moon, Bongjun Sur, Hwan-Soo Yoo & Seikwan Oh. (2021) Fumonisin B1-Induced Toxicity Was Not Exacerbated in Glutathione Peroxidase-1/Catalase Double Knock Out Mice. Biomolecules & Therapeutics 29:1, pages 52-57.
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Nienke M. de Wit, Sandra den Hoedt, Pilar Martinez-Martinez, Annemieke J. Rozemuller, Monique T. Mulder & Helga E. de Vries. (2019) Astrocytic ceramide as possible indicator of neuroinflammation. Journal of Neuroinflammation 16:1.
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Deanna Siow, Manjula Sunkara, Andrew Morris & Binks Wattenberg. (2015) Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. Advances in Biological Regulation 57, pages 42-54.
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Sitapriya Moorthi & Chiara Luberto. 2015. Bioactive Sphingolipids in Cancer Biology and Therapy. Bioactive Sphingolipids in Cancer Biology and Therapy 53 79 .
YE XU, JINSONG KANG, ZHAOXIN YUAN, HONGYAN LI, JING SU, YANG LI, XIAOXIA KONG, HONGYU ZHANG, WEIWEI WANG & LIANKUN SUN. (2013) Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells. Oncology Reports 29:4, pages 1483-1491.
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Chiara Mencarelli & Pilar Martinez–Martinez. (2012) Ceramide function in the brain: when a slight tilt is enough. Cellular and Molecular Life Sciences 70:2, pages 181-203.
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Babak Oskouian & Julie D. Saba. 2010. Sphingolipids as Signaling and Regulatory Molecules. Sphingolipids as Signaling and Regulatory Molecules 185 205 .
Rosa Martínez, Rosaura Navarro, Mercedes Lacort, José Ignacio Ruiz-Sanz & M. Begoña Ruiz-Larrea. (2009) Doxorubicin induces ceramide and diacylglycerol accumulation in rat hepatocytes through independent routes. Toxicology Letters 190:1, pages 86-90.
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Julie Noe, Daniela Petrusca, Natalia Rush, Ping Deng, Mary VanDemark, Evgeny Berdyshev, Yuan Gu, Patricia Smith, Kelly Schweitzer, Joseph Pilewsky, Viswanathan Natarajan, Zao Xu, Alexander G. Obukhov & Irina Petrache. (2009) CFTR Regulation of Intracellular pH and Ceramides Is Required for Lung Endothelial Cell Apoptosis. American Journal of Respiratory Cell and Molecular Biology 41:3, pages 314-323.
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Ana M. Sánchez, Sophie Malagarie-Cazenave, Nuria Olea, Diana Vara, Carmen Cuevas & Inés Díaz-Laviada. (2008) Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCζ activation. European Journal of Pharmacology 584:2-3, pages 237-245.
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