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Journal of Toxicology and Environmental Health, Part A
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Volume 71, 2008 - Issue 16
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Original Articles

The Induction of Hepatocellular Neoplasia by Trichloroacetic Acid Administered in the Drinking Water of the Male B6C3F1 Mouse

Anthony B. DeAngelo National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USACorrespondence[email protected]
,
F. Bernard Daniel National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio, USA
,
Diana M. Wong National Center for Environmental Assessment/IRIS Program, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA
&
Michael H. George National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA
Pages 1056-1068 | Received 20 Aug 2007, Accepted 08 Apr 2008, Published online: 14 Jun 2008

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Xinyue Peng, Susu Yu, Hui Lin, Fan Wu, Jiani Yang, Cheng Zhou, Luyun Zhang, Jianping Yang & Wenjuan Zhang. (2022) Time-concentration-dependent profile of histone modifications on human hepatocytes treated by trichloroacetic acid. International Journal of Environmental Health Research 32:11, pages 2376-2384.
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Articles from other publishers (18)

Chong Wang, Ying Shi, Wen Gu, Chao Wang, Yongjun Xu, Li Li, Lixia Zhang, Shaoping Zhang, Hong Zhi, Hongjie Ruan, Jian Kong, Lian Duan & Song Tang. (2023) Protective role of boron on hepatotoxicity and oxidative stress induced by trichloroacetic acid. Environmental Sciences Europe 35:1.
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Eric S. Peterson, William J. Raseman, Benjamin D. Stanford, Gretchen M. Bruce, Heather Klintworth & David Reckhow. (2023) Evaluating regulatory scenarios to limit U.S. nationwide exposure to cytotoxic haloacetic acids . AWWA Water Science 5:5.
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Chimeddulam Dalaijamts, Joseph A Cichocki, Yu-Syuan Luo, Ivan Rusyn & Weihsueh A Chiu. (2021) Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice. Toxicological Sciences 182:2, pages 168-182.
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Stanley T. Atwood, Ruth M. Lunn, Sanford C. Garner & Gloria D. Jahnke. (2019) New Perspectives for Cancer Hazard Evaluation by the Report on Carcinogens: A Case Study Using Read-Across Methods in the Evaluation of Haloacetic Acids Found as Water Disinfection By-Products. Environmental Health Perspectives 127:12.
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Aya O Balbaa, Ahmed Abd El-Fattah, Nahla M Awad & Ahmed Abdellatif. (2019) Effects of nanoscale electric fields on the histology of liver cell dysplasia. Nanomedicine 14:5, pages 515-528.
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Megumi Akiyama, Yoshihiko Matsui, Junki Kido, Taku Matsushita & Nobutaka Shirasaki. (2018) Monte-Carlo and multi-exposure assessment for the derivation of criteria for disinfection byproducts and volatile organic compounds in drinking water: Allocation factors and liter-equivalents per day. Regulatory Toxicology and Pharmacology 95, pages 161-174.
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Takeharu Wada, Kei Iwasaki, Yasushi Minobe, Mitsuhiro Wada, Shigeo Imai & Satoko Ishii. (2017) Proposal of a flow scheme for the chemical-form-based quantitative analysis of chlorine compounds in pulp for sanitary products and verification of safety. Regulatory Toxicology and Pharmacology 91, pages 109-116.
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A. Hartwig. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1955 1996 .
Hong Sik Yoo, Joseph A. Cichocki, Sungkyoon Kim, Abhishek Venkatratnam, Yasuhiro Iwata, Oksana Kosyk, Wanda Bodnar, Stephen Sweet, Anthony Knap, Terry Wade, Jerry Campbell, Harvey J. Clewell, Stepan B. Melnyk, Weihsueh A. Chiu & Ivan Rusyn. (2015) The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene. Toxicological Sciences 147:2, pages 339-349.
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Meenu Varshney, Abhijit Chandra, Rajeev Jain, Riaz Ahmad, Vipin Bihari, C. Keshava Chandran, Mohana K.R. Mudiam, Satykam Patnaik & S.K. Goel. (2015) Occupational health hazards of trichloroethylene among workers in relation to altered mRNA expression of cell cycle regulating genes (p53, p21, bax and bcl-2) and PPARA. Toxicology Reports 2, pages 748-757.
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Kathryn Z. GuytonKaren A. HoganCheryl Siegel ScottGlinda S. CooperAmbuja S. BaleLeonid KopylevStanley BaroneJr.Jr., Susan L. MakrisBarbara GlennRavi P. SubramaniamMaureen R. GwinnRebecca C. Dzubow & Weihsueh A. Chiu. (2014) Human Health Effects of Tetrachloroethylene: Key Findings and Scientific Issues. Environmental Health Perspectives 122:4, pages 325-334.
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Meenu Varshney, Abhijit Chandra, L. K. S. Chauhan & S. K. Goel. (2013) In vitro cytogenetic assessment of trichloroacetic acid in human peripheral blood lymphocytes. Environmental Science and Pollution Research 21:2, pages 843-850.
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Meenu Varshney, Abhijit Chandra, L. K. S. Chauhan & Sudhir K. Goel. (2013) Micronucleus induction by oxidative metabolites of trichloroethylene in cultured human peripheral blood lymphocytes: a comparative genotoxicity study. Environmental Science and Pollution Research 20:12, pages 8709-8716.
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Amr A. Fouad, Abdulruhman S. Al-Mulhim & Iyad Jresat. (2013) Therapeutic effect of coenzyme Q10 against experimentally-induced hepatocellular carcinoma in rats. Environmental Toxicology and Pharmacology 35:1, pages 100-108.
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Weihsueh A. Chiu. (2011) Trichloroacetic acid: Updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly. Toxicology 285:3, pages 114-125.
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Weihsueh A. Chiu & Gary L. Ginsberg. (2011) Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans. Toxicology and Applied Pharmacology 253:3, pages 203-234.
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Nabil M. Abdel-Hamid. (2009) Premalignant Variations in Extracellular Matrix Composition in Chemically Induced Hepatocellular Carcinoma in Rats. Journal of Membrane Biology 230:3, pages 155-162.
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Lisa M. Sweeney, Christopher R. Kirman, Michael L. Gargas & Paul H. Dugard. (2009) Contribution of trichloroacetic acid to liver tumors observed in perchloroethylene (perc)-exposed mice. Toxicology 260:1-3, pages 77-83.
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