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Original Articles

Research Issues Underlying the Four-Lab Study: Integrated Disinfection By-Products Mixtures Research

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Pages 1125-1132 | Published online: 17 Jul 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Armindo Melo, Cláudia Ferreira, Isabel M.P.L.V.O. Ferreira & Catarina Mansilha. (2019) Acute and chronic toxicity assessment of haloacetic acids using Daphnia magna. Journal of Toxicology and Environmental Health, Part A 82:18, pages 977-989.
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Pedro Gouveia, Fátima Felgueiras, Zenaida Mourão, Eduardo De Oliveira Fernandes, André Moreira & Marta Fonseca Gabriel. (2019) Predicting health risk from exposure to trihalomethanes in an Olympic-size indoor swimming pool among elite swimmers and coaches. Journal of Toxicology and Environmental Health, Part A 82:9, pages 577-590.
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Steve E. Hrudey, Lorraine C. Backer, Andrew R. Humpage, Stuart W. Krasner, Dominique S. Michaud, Lee E. Moore, Philip C. Singer & Benjamin D. Stanford. (2015) Evaluating Evidence for Association of Human Bladder Cancer with Drinking-Water Chlorination Disinfection By-Products. Journal of Toxicology and Environmental Health, Part B 18:5, pages 213-241.
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Zelinda Isabel Silva, Maria Helena Rebelo, Manuela Manso Silva, Ana Martins Alves, Maria da Conceição Cabral, Ana Cristina Almeida, Fátima Rôxo Aguiar, Anabela Lopes de Oliveira, Ana Cruz Nogueira, Hermínia Rodrigues Pinhal, Pedro Manuel Aguiar & Ana Sofia Cardoso. (2012) Trihalomethanes in Lisbon Indoor Swimming Pools: Occurrence, Determining Factors, and Health Risk Classification. Journal of Toxicology and Environmental Health, Part A 75:13-15, pages 878-892.
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GlennE. Rice, LindaK. Teuschler, RichardJ. Bull, JaneE. Simmons & PaulI. Feder. (2009) Evaluating the Similarity of Complex Drinking-Water Disinfection By-Product Mixtures: Overview of the Issues. Journal of Toxicology and Environmental Health, Part A 72:7, pages 429-436.
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Glenn Rice, LindaK. Teuschler, ThomasF. Speth, SusanD. Richardson, RichardJ. Miltner, KathleenM. Schenck, Chris Gennings, E. Sidney Hunter$suffix/text()$suffix/text(), MichaelG. Narotsky & Jane Ellen Simmons. (2008) Integrated Disinfection By-Products Research: Assessing Reproductive and Developmental Risks Posed by Complex Disinfection By-Product Mixtures. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1222-1234.
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MichaelG. Narotsky, DeborahS. Best, EllenH. Rogers, Anthony McDonald, YusuphaM. Sey & Jane Ellen Simmons. (2008) Integrated Disinfection By-Products Mixtures Research: Assessment of Developmental Toxicity in Sprague-Dawley Rats Exposed to Concentrates of Water Disinfected by Chlorination and Ozonation/Postchlorination. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1216-1221.
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LynnM. Crosby, Jane Ellen Simmons, WilliamO. Ward, TanyaM. Moore, KevinT. Morgan & AnthonyB. DeAngelo. (2008) Integrated Disinfection By-Products (DBP) Mixtures Research: Gene Expression Alterations in Primary Rat Hepatocyte Cultures Exposed to DBP Mixtures Formed by Chlorination and Ozonation/Postchlorination. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1195-1215.
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LarryD. Claxton, Rex Pegram, KathleenM. Schenck, Jane Ellen Simmons & SarahH. Warren. (2008) Integrated Disinfection By-Products Research: Salmonella Mutagenicity of Water Concentrates Disinfected by Chlorination and Ozonation/Postchlorination. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1187-1194.
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SusanD. Richardson, AlfredD. Thruston$suffix/text()$suffix/text(), StuartW. Krasner, HowardS. Weinberg, RichardJ. Miltner, KathleenM. Schenck, MichaelG. Narotsky, A. Bruce McKague & Jane Ellen Simmons. (2008) Integrated Disinfection By-Products Mixtures Research: Comprehensive Characterization of Water Concentrates Prepared from Chlorinated and Ozonated/Postchlorinated Drinking Water. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1165-1186.
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ThomasF. Speth, RichardJ. Miltner, SusanD. Richardson & Jane Ellen Simmons. (2008) Integrated Disinfection By-Products Mixtures Research: Concentration by Reverse Osmosis Membrane Techniques of Disinfection By-Products from Water Disinfected by Chlorination and Ozonation/Postchlorination. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1149-1164.
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RichardJ. Miltner, ThomasF. Speth, SusanD. Richardson, StuartW. Krasner, HowardS. Weinberg & Jane Ellen Simmons. (2008) Integrated Disinfection By-Products Mixtures Research: Disinfection of Drinking Waters by Chlorination and Ozonation/Postchlorination Treatment Scenarios. Journal of Toxicology and Environmental Health, Part A 71:17, pages 1133-1148.
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Articles from other publishers (26)

Li‐Tang Qin, Min Liu, Xin Zhang, Ling‐Yun Mo, Hong‐Hu Zeng & Yan‐Peng Liang. (2021) Concentration Addition, Independent Action, and Quantitative Structure–Activity Relationships for Chemical Mixture Toxicities of the Disinfection By products of Haloacetic Acids on the Green Alga Raphidocelis subcapitata . Environmental Toxicology and Chemistry 40:5, pages 1431-1442.
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Xin-Yang Zhang, Yao Lu, Ye Du, Wen-Long Wang, Lu-Lin Yang & Qian-Yuan Wu. (2021) Comprehensive GC×GC-qMS with a mass-to-charge ratio difference extraction method to identify new brominated byproducts during ozonation and their toxicity assessment. Journal of Hazardous Materials 403, pages 124103.
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Raquel S. Chaves, Catarina S. Guerreiro, Vítor V. Cardoso, Maria J. Benoliel & Miguel M. Santos. (2020) Toxicological assessment of seven unregulated drinking water Disinfection By-products (DBPs) using the zebrafish embryo bioassay. Science of The Total Environment 742, pages 140522.
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Eva-Maria Buchner, Oliver Happel, Carsten K. Schmidt, Marco Scheurer, Beat Schmutz, Meike Kramer, Martina Knauer, Stefan Gartiser & Henner Hollert. (2019) Approach for analytical characterization and toxicological assessment of ozonation products in drinking water on the example of acesulfame. Water Research 153, pages 357-368.
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Xing-Fang Li & William A. Mitch. (2018) Drinking Water Disinfection Byproducts (DBPs) and Human Health Effects: Multidisciplinary Challenges and Opportunities. Environmental Science & Technology 52:4, pages 1681-1689.
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R.S.H. Yang. 2018. Comprehensive Toxicology. Comprehensive Toxicology 489 518 .
Cynthia V. Rider, Gregg E. Dinse, David M. Umbach, Jane Ellen Simmons & Richard C. Hertzberg. 2018. Chemical Mixtures and Combined Chemical and Nonchemical Stressors. Chemical Mixtures and Combined Chemical and Nonchemical Stressors 235 270 .
Glenn E. Rice, Ingvar Eide, Paul I. Feder & Chris Gennings. 2018. Chemical Mixtures and Combined Chemical and Nonchemical Stressors. Chemical Mixtures and Combined Chemical and Nonchemical Stressors 421 463 .
Jane Ellen Simmons, Ingvar Eide, Glenn Rice & Paul Feder. 2018. Chemical Mixtures and Combined Chemical and Nonchemical Stressors. Chemical Mixtures and Combined Chemical and Nonchemical Stressors 335 366 .
Shahid Parvez, Glenn E. Rice, Linda K. Teuschler, Jane Ellen Simmons, Thomas F. Speth, Susan D. Richardson, Richard J. Miltner, E. Sidney HunterIIIIII, Jonathan G. Pressman, Lillian F. Strader, Gary R. Klinefelter, Jerome M. Goldman & Michael G. Narotsky. (2017) Method to assess component contribution to toxicity of complex mixtures: Assessment of puberty acquisition in rats exposed to disinfection byproducts. Journal of Environmental Sciences 58, pages 311-321.
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Robert Benson, Octavia D. Conerly, William Sander, Angela L. Batt, J. Scott Boone, Edward T. Furlong, Susan T. Glassmeyer, Dana W. Kolpin, Heath E. Mash, Kathleen M. Schenck & Jane Ellen Simmons. (2017) Human health screening and public health significance of contaminants of emerging concern detected in public water supplies. Science of The Total Environment 579, pages 1643-1648.
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Chunmei Li, Donghong Wang, Na Li, Qian Luo, Xiong Xu & Zijian Wang. (2016) Identifying unknown by-products in drinking water using comprehensive two-dimensional gas chromatography–quadrupole mass spectrometry and in silico toxicity assessment. Chemosphere 163, pages 535-543.
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Elisabet Teixidó, Esther Piqué, Javier Gonzalez-Linares, Joan M. Llobet & Jesús Gómez-Catalán. (2015) Developmental effects and genotoxicity of 10 water disinfection by-products in zebrafish. Journal of Water and Health 13:1, pages 54-66.
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Barbara Werschkun, Sangeeta Banerji, Oihane C. Basurko, Matej David, Frank Fuhr, Stephan Gollasch, Tamara Grummt, Michael Haarich, Awadhesh N. Jha, Stefan Kacan, Anja Kehrer, Jan Linders, Ehsan Mesbahi, Dandu Pughiuc, Susan D. Richardson, Beatrice Schwarz-Schulz, Amisha Shah, Norbert Theobald, Urs von Gunten, Stefanie Wieck & Thomas Höfer. (2014) Emerging risks from ballast water treatment: The run-up to the International Ballast Water Management Convention. Chemosphere 112, pages 256-266.
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Michael G. Narotsky, Gary R. Klinefelter, Jerome M. Goldman, Deborah S. Best, Anthony McDonald, Lillian F. Strader, Juan D. Suarez, Ashley S. Murr, Inthirany Thillainadarajah, E. Sidney HunterIIIIII, Susan D. Richardson, Thomas F. Speth, Richard J. Miltner, Jonathan G. Pressman, Linda K. Teuschler, Glenn E. Rice, Virginia C. Moser, Robert W. Luebke & Jane Ellen Simmons. (2013) Comprehensive Assessment of a Chlorinated Drinking Water Concentrate in a Rat Multigenerational Reproductive Toxicity Study. Environmental Science & Technology, pages 130828135946008.
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Shu Wang, Dajun Tian, Weiwei Zheng, Songhui Jiang, Xia Wang, Melvin E. Andersen, Yuxin Zheng, Gensheng He & Weidong Qu. (2013) Combined Exposure to 3-Chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone and Microsytin-LR Increases Genotoxicity in Chinese Hamster Ovary Cells through Oxidative Stress. Environmental Science & Technology, pages 130110124508007.
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Eileen A. MurphyGloria B. Post, Brian T. BuckleyRobert L. Lippincott & Mark G. Robson. (2012) Future Challenges to Protecting Public Health from Drinking-Water Contaminants. Annual Review of Public Health 33:1, pages 209-224.
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Cheryl A. Dingus, Linda K. Teuschler, Glenn E. Rice, Jane Ellen Simmons & Michael G. Narotsky. (2011) Prospective Power Calculations for the Four Lab Study of A Multigenerational Reproductive/Developmental Toxicity Rodent Bioassay Using A Complex Mixture of Disinfection By-Products in the Low-Response Region. International Journal of Environmental Research and Public Health 8:10, pages 4082-4101.
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Joan Colman, Glenn E. Rice, J. Michael Wright, E. Sidney HunterIIIIII, Linda K. Teuschler, John C. Lipscomb, Richard C. Hertzberg, Jane Ellen Simmons, Margaret Fransen, Mark Osier & Michael G. Narotsky. (2011) Identification of developmentally toxic drinking water disinfection byproducts and evaluation of data relevant to mode of action. Toxicology and Applied Pharmacology 254:2, pages 100-126.
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Susan D. Richardson & Cristina Postigo. 2012. Emerging Organic Contaminants and Human Health. Emerging Organic Contaminants and Human Health 93 137 .
Jonathan G. PressmanSusan D. RichardsonThomas F. SpethRichard J. MiltnerMichael G. NarotskyE. Sidney Hunter, IIIGlenn E. RiceLinda K. TeuschlerAnthony McDonaldShahid ParvezStuart W. KrasnerHoward S. WeinbergA. Bruce McKagueChristopher J. ParrettNathalie BodinRussell ChinnChih-Fen T. LeeJane Ellen Simmons. (2010) Concentration, Chlorination, and Chemical Analysis of Drinking Water for Disinfection Byproduct Mixtures Health Effects Research: U.S. EPA’s Four Lab Study. Environmental Science & Technology 44:19, pages 7184-7192.
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Jane Ellen Simmons & Linda K. Teuschler. 2010. Principles and Practice of Mixtures Toxicology. Principles and Practice of Mixtures Toxicology 401 419 .
Sara Rodriguez-Mozaz & Howard S. Weinberg. (2010) Meeting Report: Pharmaceuticals in Water—An Interdisciplinary Approach to a Public Health Challenge. Environmental Health Perspectives 118:7, pages 1016-1020.
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Royce A. Francis, Jeanne M. VanBriesen & Mitchell J. Small. (2010) Bayesian Statistical Modeling of Disinfection Byproduct (DBP) Bromine Incorporation in the ICR Database. Environmental Science & Technology 44:4, pages 1232-1239.
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A Mcdonald, P Killough, E Puckett, D S Best, J E Simmons, J G Pressman & M G Narotsky. (2010) A novel water delivery system for administering volatile chemicals while minimizing chemical waste in rodent toxicity studies. Laboratory Animals 44:1, pages 66-68.
Crossref
R.S.H. Yang. 2010. Comprehensive Toxicology. Comprehensive Toxicology 179 202 .

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