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Journal of Toxicology and Environmental Health, Part A
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Volume 74, 2011 - Issue 21: Bioactivity of Oil Dispersant in the Deepwater Horizon Clean-up Operation
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Original Articles

Neurotoxicity Following Acute Inhalation Exposure to the Oil Dispersant COREXIT EC9500A

Krishnan Sriram Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USACorrespondence[email protected]
,
Gary X. Lin Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Amy M. Jefferson Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
William T. Goldsmith Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Mark Jackson Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Walter McKinney Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
David G. Frazer Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
,
Victor A. Robinson Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
&
Vincent Castranova Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
 show all
Pages 1405-1418 | Published online: 14 Sep 2011

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Kevin M. Stroski, Gregg Tomy & Vince Palace. (2019) The current state of knowledge for toxicity of corexit EC9500A dispersant: a review. Critical Reviews in Environmental Science and Technology 49:2, pages 81-103.
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Lawrence S. Engel, Richard K. Kwok, Aubrey K. Miller, Aaron Blair, Matthew D. Curry, John A. McGrath & Dale P. Sandler. (2017) The Gulf Long-Term Follow-Up Study (GuLF STUDY): Biospecimen collection at enrollment. Journal of Toxicology and Environmental Health, Part A 80:4, pages 218-229.
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Blanca Laffon, Eduardo Pásaro & Vanessa Valdiglesias. (2016) Effects of exposure to oil spills on human health: Updated review. Journal of Toxicology and Environmental Health, Part B 19:3-4, pages 105-128.
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Rachel Aileen Brewton, Richard Fulford & Robert J. Griffitt. (2013) Gene Expression and Growth as Indicators of Effects of the BP Deepwater Horizon Oil Spill on Spotted Seatrout (Cynoscion nebulosus). Journal of Toxicology and Environmental Health, Part A 76:21, pages 1198-1209.
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Yongli Shi, Astrid M. Roy-Engel & He Wang. (2013) Effects of Corexit Dispersants on Cytotoxicity Parameters in a Cultured Human Bronchial Airway Cells, BEAS-2B. Journal of Toxicology and Environmental Health, Part A 76:13, pages 827-835.
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William Travis Goldsmith, Walter McKinney, Mark Jackson, Brandon Law, Toni Bledsoe, Paul Siegel, Jared Cumpston & David Frazer. (2011) A Computer-Controlled Whole-Body Inhalation Exposure System for the Oil Dispersant COREXIT EC9500A. Journal of Toxicology and Environmental Health, Part A 74:21, pages 1368-1380.
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Articles from other publishers (22)

Sreekumar Othumpangat & Jeffrey S. Fedan. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 79 83 .
Abdurrashid Haruna, Gazali Tanimu, Ismaila Ibrahim, Zaharaddeen Nasiru Garba, Sharhabil Musa Yahaya, Suleiman Gani Musa & Zulkifli Merican Aljunid Merican. (2023) Mitigating oil and gas pollutants for a sustainable environment – Critical review and prospects. Journal of Cleaner Production 416, pages 137863.
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Yong Yang, Wanze Zhang, Zhanwei Zhang, Ting Yang, Zhuo Xu, Chuanbo Zhang, Bing Guo & Wenyu Lu. (2023) Efficient Bioremediation of Petroleum-Contaminated Soil by Immobilized Bacterial Agent of Gordonia alkanivorans W33. Bioengineering 10:5, pages 561.
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Dhruba Pathak & Krishnan Sriram. (2023) Molecular Mechanisms Underlying Neuroinflammation Elicited by Occupational Injuries and Toxicants. International Journal of Molecular Sciences 24:3, pages 2272.
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Krishnan Sriram, Gary X. Lin, Amy M. Jefferson, Walter McKinney, Mark C. Jackson, Jared L. Cumpston, James B. Cumpston, Howard D. Leonard, Michael L. Kashon & Jeffrey S. Fedan. (2022) Biological effects of inhaled crude oil vapor V. Altered biogenic amine neurotransmitters and neural protein expression. Toxicology and Applied Pharmacology 449, pages 116137.
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Susan Arnold, Patricia A Stewart, Gregory C Pratt, Gurumurthy Ramachandran, Richard K Kwok, Lawrence S Engel, Dale P Sandler & Mark R Stenzel. (2022) Estimation of Aerosol Concentrations of Oil Dispersants COREXIT™ EC9527A and EC9500A during the Deepwater Horizon Oil Spill Response and Clean-up Operations . Annals of Work Exposures and Health 66:Supplement_1, pages i188-i202.
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Dana Stahl. 2020. Health and Safety in Emergency Management and Response. Health and Safety in Emergency Management and Response 1 37 .
Innocent Chukwunonso Ossai, Aziz Ahmed, Auwalu Hassan & Fauziah Shahul Hamid. (2020) Remediation of soil and water contaminated with petroleum hydrocarbon: A review. Environmental Technology & Innovation 17, pages 100526.
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Fei Guo, Daniela de Lima Stebbins, Ryan G. Toomey & Norma A. Alcantar. (2019) Interfacial Phenomena of Natural Dispersants for Crude Oil Spills. Langmuir 35:48, pages 15904-15913.
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Yajie Hou, Yiming Li, Lisha Wang, Dafan Chen, Mutai Bao & Zhining Wang. (2019) Amphiphilic Janus particles for efficient dispersion of oil contaminants in seawater. Journal of Colloid and Interface Science 556, pages 54-64.
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Jayasree Krishnamurthy, Lawrence S. Engel, Li Wang, Erica G. Schwartz, Kate Christenbury, Benjamin Kondrup, John Barrett & Jennifer A. Rusiecki. (2019) Neurological symptoms associated with oil spill response exposures: Results from the Deepwater Horizon Oil Spill Coast Guard Cohort Study. Environment International 131, pages 104963.
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Nima Afshar-Mohajer, Mary A. Fox & Kirsten Koehler. (2019) The human health risk estimation of inhaled oil spill emissions with and without adding dispersant. Science of The Total Environment 654, pages 924-932.
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James Matcott, Shane Baylis & Rohan H. Clarke. (2019) The influence of petroleum oil films on the feather structure of tropical and temperate seabird species. Marine Pollution Bulletin 138, pages 135-144.
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Marusia Popovech. (2017) Analysis of Hazards of Dispersant Constituents and Review of Toxicological Studies. International Oil Spill Conference Proceedings 2017:1, pages 311-330.
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Christine V. Fiorello, Kate Freeman, Becky A. Elias, Emily Whitmer & Michael H. Ziccardi. (2016) Ophthalmic effects of petroleum dispersant exposure on common murres (Uria aalge): An experimental study. Marine Pollution Bulletin 113:1-2, pages 387-391.
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Yanling Chen & David H. Reese. (2016) Corexit-EC9527A Disrupts Retinol Signaling and Neuronal Differentiation in P19 Embryonal Pluripotent Cells. PLOS ONE 11:9, pages e0163724.
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Dwipayan Bhattacharya, T. Prabhakar Clement & Muralikrishnan Dhanasekaran. (2016) Evaluating the neurotoxic effects of Deepwater Horizon oil spill residues trapped along Alabama's beaches. Life Sciences 155, pages 161-166.
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Roger C. Prince. (2015) Oil Spill Dispersants: Boon or Bane?. Environmental Science & Technology 49:11, pages 6376-6384.
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Fu Jun Li, Ryan N. Duggal, Octavio M. Oliva, Suman Karki, Ranu Surolia, Zheng Wang, R. Douglas Watson, Victor J. Thannickal, Mickie Powell, Stephen Watts, Tejaswini Kulkarni, Hitesh Batra, Subhashini Bolisetty, Anupam Agarwal & Veena B. Antony. (2015) Heme Oxygenase-1 Protects Corexit 9500A-Induced Respiratory Epithelial Injury across Species. PLOS ONE 10:4, pages e0122275.
Crossref
Jenny R. RobertsStacey E. AndersonHong KanKristine KrajnakJanet A. ThompsonAllison KenyonWilliam T. GoldsmithWalter McKinneyDavid G. FrazerMark JacksonJeffrey S. Fedan. (2015) Evaluation of Pulmonary and Systemic Toxicity of Oil Dispersant (COREXIT EC9500A ® ) following Acute Repeated Inhalation Exposure . Environmental Health Insights 8s1, pages EHI.S15262.
Crossref
Mengyuan Zheng, Manuj Ahuja, Dwipayan Bhattacharya, T. Prabhakar Clement, Joel S. Hayworth & Muralikrishnan Dhanasekaran. (2014) Evaluation of differential cytotoxic effects of the oil spill dispersant Corexit 9500. Life Sciences 95:2, pages 108-117.
Crossref
Yanqiong Zhang, Dongliang Chen, Adrien C. Ennis, Joseph R. Polli, Peng Xiao, Baohong Zhang, Edmund J. Stellwag, Anthony Overton & Xiaoping Pan. (2012) Chemical dispersant potentiates crude oil impacts on growth, reproduction, and gene expression in Caenorhabditis elegans. Archives of Toxicology 87:2, pages 371-382.
Crossref

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