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Original Articles

Potential Immunotoxicological Health Effects Following Exposure to COREXIT 9500A during Cleanup of the Deepwater Horizon Oil Spill

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Pages 1419-1430 | Published online: 14 Sep 2011

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Read on this site (8)

Ryan Takeshita, Steven J. Bursian, Kathleen M. Colegrove, Tracy K. Collier, Kristina Deak, Karen M. Dean, Sylvain De Guise, Lisa M. DiPinto, Cornelis J. Elferink, Andrew J. Esbaugh, Robert J. Griffitt, Martin Grosell, Kendal E. Harr, John P. Incardona, Richard K. Kwok, Joshua Lipton, Carys L. Mitchelmore, Jeffrey M. Morris, Edward S. Peters, Aaron P. Roberts, Teresa K. Rowles, Jennifer A. Rusiecki, Lori H. Schwacke, Cynthia R. Smith, Dana L. Wetzel, Michael H. Ziccardi & Ailsa J. Hall. (2021) A review of the toxicology of oil in vertebrates: what we have learned following the Deepwater Horizon oil spill. Journal of Toxicology and Environmental Health, Part B 24:8, pages 355-394.
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Kevin M. Stroski, Gregg Tomy & Vince Palace. (2019) The current state of knowledge for toxicity of corexit EC9500A dispersant: a review. Critical Reviews in Environmental Science and Technology 49:2, pages 81-103.
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Mahesh Raj Nepal, Youra Kang, Mi Jeong Kang, Doo Hyun Nam & Tae Cheon Jeong. (2018) A β-galactosidase-expressing E. coli culture as an alternative test to identify skin sensitizers and non-sensitizers. Journal of Toxicology and Environmental Health, Part A 81:9, pages 288-301.
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Lawrence S. Engel, Richard K. Kwok, Aubrey K. Miller, Aaron Blair, Matthew D. Curry, John A. McGrath & Dale P. Sandler. (2017) The Gulf Long-Term Follow-Up Study (GuLF STUDY): Biospecimen collection at enrollment. Journal of Toxicology and Environmental Health, Part A 80:4, pages 218-229.
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Blanca Laffon, Eduardo Pásaro & Vanessa Valdiglesias. (2016) Effects of exposure to oil spills on human health: Updated review. Journal of Toxicology and Environmental Health, Part B 19:3-4, pages 105-128.
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Aliaksandr Vasily Yeudakimau, Christopher Regnier Perkins, Gina Maren Guerrera, James Davies Stuart & Anthony Athanasios Provatas. (2014) QuEChERS sample preparation followed by ultra-performance liquid chromatography – tandem mass spectrometry for rapid screening of dioctyl sulfosuccinate sodium salt in avian egg tissue. International Journal of Environmental Analytical Chemistry 94:12, pages 1183-1198.
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Rachel Aileen Brewton, Richard Fulford & Robert J. Griffitt. (2013) Gene Expression and Growth as Indicators of Effects of the BP Deepwater Horizon Oil Spill on Spotted Seatrout (Cynoscion nebulosus). Journal of Toxicology and Environmental Health, Part A 76:21, pages 1198-1209.
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Yongli Shi, Astrid M. Roy-Engel & He Wang. (2013) Effects of Corexit Dispersants on Cytotoxicity Parameters in a Cultured Human Bronchial Airway Cells, BEAS-2B. Journal of Toxicology and Environmental Health, Part A 76:13, pages 827-835.
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Articles from other publishers (25)

Stacey E. Anderson, Courtney E. W. Sulentic & Barbara L. F. Kaplan. 2003. Patty's Toxicology. Patty's Toxicology 1 55 .
Zhongbao Zhang, Hao Li, Ting Xu, Haowan Xu, Shaoting He, Zaixin Li & Zhi Zhang. (2021) Jianqu fermentation with the isolated fungi significantly improves the immune response in immunosuppressed mice. Journal of Ethnopharmacology 267, pages 113512.
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Jesse M Kemp, Lerin R Luckett-Chastain, Kaitlin N Calhoun, Benjamin Frempah, Tayler R Schartz, Linda E Harty, Philip M Kemp & Randle M Gallucci. (2020) Evaluation of skin irritation following weathered crude oil exposure in two mouse strains. Toxicology and Industrial Health 36:10, pages 788-799.
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Dana Stahl. 2020. Health and Safety in Emergency Management and Response. Health and Safety in Emergency Management and Response 1 37 .
Jay C. Fernandes, Niti R. Agrawal, Futoon O. Aljirafi, Geoffrey D. Bothun, Alon V. McCormick, Vijay T. John & Srinivasa R. Raghavan. (2019) Does the Solvent in a Dispersant Impact the Efficiency of Crude-Oil Dispersion?. Langmuir 35:50, pages 16630-16639.
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Fei Guo, Daniela de Lima Stebbins, Ryan G. Toomey & Norma A. Alcantar. (2019) Interfacial Phenomena of Natural Dispersants for Crude Oil Spills. Langmuir 35:48, pages 15904-15913.
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Kuttuvan Valappil Sajna & Lalitha Devi Gottumukkala. 2019. Microbes and Enzymes in Soil Health and Bioremediation. Microbes and Enzymes in Soil Health and Bioremediation 353 378 .
Charles M. Luft, Elango Munusamy, Jeanne E. Pemberton & Steven D. Schwartz. (2018) Molecular Dynamics Simulation of the Oil Sequestration Properties of a Nonionic Rhamnolipid. The Journal of Physical Chemistry B 122:14, pages 3944-3952.
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Sindhu Ramesh, Dwipayan Bhattacharya, Mohammed Majrashi, Marlee Morgan, T. Prabhakar Clement & Muralikrishnan Dhanasekaran. (2018) Evaluation of behavioral parameters, hematological markers, liver and kidney functions in rodents exposed to Deepwater Horizon crude oil and Corexit. Life Sciences 199, pages 34-40.
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Christopher StevensLouis. J. ThibodeauxEdward. B. OvertonKalliat T. ValsarajNan D. Walker. (2017) Dissolution and Heavy Residue Sinking of Subsurface Oil Droplets: Binary Component Mixture Dissolution Theory and Model-Oil Experiments. Journal of Environmental Engineering 143:10.
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Craig J. McGowan, Richard K. Kwok, Lawrence S. Engel, Mark R. Stenzel, Patricia A. Stewart & Dale P. Sandler. (2017) Respiratory, Dermal, and Eye Irritation Symptoms Associated with Corexit™ EC9527A/EC9500A following the Deepwater Horizon Oil Spill: Findings from the GuLF STUDY . Environmental Health Perspectives 125:9.
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Maureen Lichtveld, Samendra Sherchan, Kaitlyn B. Gam, Richard K. Kwok, Christopher Mundorf, Arti Shankar & Lissa Soares. (2016) The Deepwater Horizon Oil Spill Through the Lens of Human Health and the Ecosystem. Current Environmental Health Reports 3:4, pages 370-378.
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Laurence N. Warr, André Friese, Florian Schwarz, Frieder Schauer, Ralph J. Portier, Laura M. Basirico & Gregory M. Olson. (2016) Experimental study of clay-hydrocarbon interactions relevant to the biodegradation of the Deepwater Horizon oil from the Gulf of Mexico. Chemosphere 162, pages 208-221.
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Yanling Chen & David H. Reese. (2016) Corexit-EC9527A Disrupts Retinol Signaling and Neuronal Differentiation in P19 Embryonal Pluripotent Cells. PLOS ONE 11:9, pages e0163724.
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Danielle Major, Rebecca S. Derbes, He Wang & Astrid M. Roy-Engel. (2016) Effects of corexit oil dispersants and the WAF of dispersed oil on DNA damage and repair in cultured human bronchial airway cells, BEAS-2B. Gene Reports 3, pages 22-30.
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Bo Wang, Nicholas K. Geitner, Thomas P. Davis, Pu Chun Ke, David A. Ladner & Feng Ding. (2015) Deviation from the Unimolecular Micelle Paradigm of PAMAM Dendrimers Induced by Strong Interligand Interactions. The Journal of Physical Chemistry C 119:33, pages 19475-19484.
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Roger C. Prince. (2015) Oil Spill Dispersants: Boon or Bane?. Environmental Science & Technology 49:11, pages 6376-6384.
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Fu Jun Li, Ryan N. Duggal, Octavio M. Oliva, Suman Karki, Ranu Surolia, Zheng Wang, R. Douglas Watson, Victor J. Thannickal, Mickie Powell, Stephen Watts, Tejaswini Kulkarni, Hitesh Batra, Subhashini Bolisetty, Anupam Agarwal & Veena B. Antony. (2015) Heme Oxygenase-1 Protects Corexit 9500A-Induced Respiratory Epithelial Injury across Species. PLOS ONE 10:4, pages e0122275.
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Charlotte Bodinier, Fernando Galvez, Katherine Gautreaux, Arianna Rivera & Christopher Green. 2014. Impacts of Oil Spill Disasters on Marine Habitats and Fisheries in North America. Impacts of Oil Spill Disasters on Marine Habitats and Fisheries in North America 35 52 .
Joseph Ryan Polli, Yanqiong Zhang & Xiaoping Pan. (2014) Dispersed crude oil amplifies germ cell apoptosis in Caenorhabditis elegans, followed a CEP-1-dependent pathway. Archives of Toxicology.
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Jenny R. RobertsStacey E. AndersonHong KanKristine KrajnakJanet A. ThompsonAllison KenyonWilliam T. GoldsmithWalter McKinneyDavid G. FrazerMark JacksonJeffrey S. Fedan. (2015) Evaluation of Pulmonary and Systemic Toxicity of Oil Dispersant (COREXIT EC9500A ® ) following Acute Repeated Inhalation Exposure . Environmental Health Insights 8s1, pages EHI.S15262.
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Mengyuan Zheng, Manuj Ahuja, Dwipayan Bhattacharya, T. Prabhakar Clement, Joel S. Hayworth & Muralikrishnan Dhanasekaran. (2014) Evaluation of differential cytotoxic effects of the oil spill dispersant Corexit 9500. Life Sciences 95:2, pages 108-117.
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Blanca Laffon, Francisco Aguilera, Julia Ríos-Vázquez, Julia García-Lestón, Dietmar Fuchs, Vanessa Valdiglesias & Eduardo Pásaro. (2013) Endocrine and immunological parameters in individuals involved in Prestige spill cleanup tasks seven years after the exposure. Environment International 59, pages 103-111.
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Yanqiong Zhang, Dongliang Chen, Adrien C. Ennis, Joseph R. Polli, Peng Xiao, Baohong Zhang, Edmund J. Stellwag, Anthony Overton & Xiaoping Pan. (2012) Chemical dispersant potentiates crude oil impacts on growth, reproduction, and gene expression in Caenorhabditis elegans. Archives of Toxicology 87:2, pages 371-382.
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Nicholas K. Geitner, Rhonda R. Powell, Terri Bruce, David A. Ladner & Pu Chun Ke. (2013) Effects of dendrimer oil dispersants on Dictyostelium discoideum. RSC Advances 3:48, pages 25930.
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