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Original Articles

Determination of TiO2, ZrO2, and Al2O3 Nanoparticles on Genotoxic Responses in Human Peripheral Blood Lymphocytes and Cultured Embyronic Kidney Cells

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Pages 990-1002 | Received 26 Jul 2013, Accepted 29 Jul 2013, Published online: 24 Oct 2013

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Read on this site (6)

Peter Møller, Ditte Marie Jensen, Regitze Sølling Wils, Maria Helena Guerra Andersen, Pernille Høgh Danielsen & Martin Roursgaard. (2017) Assessment of evidence for nanosized titanium dioxide-generated DNA strand breaks and oxidatively damaged DNA in cells and animal models. Nanotoxicology 11:9-10, pages 1237-1256.
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Eşref Demir, Amadeu Creus & Ricard Marcos. (2014) Genotoxicity and DNA Repair Processes of Zinc Oxide Nanoparticles. Journal of Toxicology and Environmental Health, Part A 77:21, pages 1292-1303.
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. (2016) Re-evaluation of titanium dioxide (E 171) as a food additive. EFSA Journal 14:9, pages e04545.
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Elham Asadpour, Hamid R. Sadeghnia, Ahmad Ghorbani, Mehran Sedaghat & Mohammad T. Boroushaki. (2016) Oxidative stress-mediated cytotoxicity of zirconia nanoparticles on PC12 and N2a cells. Journal of Nanoparticle Research 18:1.
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Preeyaporn Koedrith, Rattana Boonprasert, Jee Young Kwon, Im-Soon Kim & Young Rok Seo. (2014) Recent toxicological investigations of metal or metal oxide nanoparticles in mammalian models in vitro and in vivo: DNA damaging potential, and relevant physicochemical characteristics. Molecular & Cellular Toxicology 10:2, pages 107-126.
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Zhangjian Chen, Yun Wang, Te Ba, Yang Li, Ji Pu, Tian Chen, Yanshuang Song, Yongen Gu, Qin Qian, Jinglin Yang & Guang Jia. (2014) Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro. Toxicology Letters 226:3, pages 314-319.
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Tao Chen, Jian Yan & Yan Li. (2014) Genotoxicity of titanium dioxide nanoparticles. Journal of Food and Drug Analysis 22:1, pages 95-104.
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