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Original Articles

Genotoxicity and DNA Repair Processes of Zinc Oxide Nanoparticles

, &
Pages 1292-1303 | Received 29 Apr 2014, Accepted 12 Jun 2014, Published online: 30 Sep 2014

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Samar Sakr & Vanessa Steenkamp. (2021) Zinc oxide nanoparticles induce oxidative stress and histopathological toxicity in the thyroid gland and liver of rats. Toxicological & Environmental Chemistry 103:4, pages 399-422.
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Sanjiv Singh. (2019) Zinc oxide nanoparticles impacts: cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity. Toxicology Mechanisms and Methods 29:4, pages 300-311.
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Seetharam Deepa, Raju Murugananthkumar, Yugantak Raj Gupta, Manjunatha Gowda K.S & Balasubramanian Senthilkumaran. (2019) Effects of zinc oxide nanoparticles and zinc sulfate on the testis of common carp, Cyprinus carpio. Nanotoxicology 13:2, pages 240-257.
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Cheng Teng Ng, Liang Qing Yong, Manoor Prakash Hande, Choon Nam Ong, Liya E Yu, Boon Huat Bay & Gyeong Hun Baeg. (2017) Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster. International Journal of Nanomedicine 12, pages 1621-1637.
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Kyu-Bong Kim, Young Woo Kim, Seong Kwang Lim, Tae Hyun Roh, Du Yeon Bang, Seul Min Choi, Duck Soo Lim, Yeon Joo Kim, Seol-Hwa Baek, Min-Kook Kim, Hyo-Seon Seo, Min-Hwa Kim, Hyung Sik Kim, Joo Young Lee, Sam Kacew & Byung-Mu Lee. (2017) Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens. Journal of Toxicology and Environmental Health, Part B 20:3, pages 155-182.
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Zhe Han, Qi Yan, Wei Ge, Zhi-Guo Liu, Sangiliyandi Gurunathan, Massimo De Felici, Wei Shen & Xi-Feng Zhang. (2016) Cytotoxic effects of ZnO nanoparticles on mouse testicular cells. International Journal of Nanomedicine 11, pages 5187-5203.
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Mohamed Alaraby, Balasubramanyam Annangi, Ricard Marcos & Alba Hernández. (2016) Drosophila melanogaster as a suitable in vivo model to determine potential side effects of nanomaterials: A review. Journal of Toxicology and Environmental Health, Part B 19:2, pages 65-104.
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Miguel Ferreira Pinto, Henriqueta Louro, Pedro M. Costa, Sandra Caeiro & Maria João Silva. (2015) Exploring the Potential Interference of Estuarine Sediment Contaminants with the DNA Repair Capacity of Human Hepatoma Cells. Journal of Toxicology and Environmental Health, Part A 78:9, pages 559-570.
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Jonghye Choi, Heyjin Kim, Pilje Kim, Eunhye Jo, Hyun-Mi Kim, Moo-Yeol Lee, Seon Mi Jin & Kwangsik Park. (2015) Toxicity of Zinc Oxide Nanoparticles in Rats Treated by Two Different Routes: Single Intravenous Injection and Single Oral Administration. Journal of Toxicology and Environmental Health, Part A 78:4, pages 226-243.
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Mostafa Vaghari-Tabari, Davoud Jafari-Gharabaghlou, Mozafar Mohammadi & Mohammad Sadegh Hashemzadeh. (2023) Zinc Oxide Nanoparticles and Cancer Chemotherapy: Helpful Tools for Enhancing Chemo-sensitivity and Reducing Side Effects?. Biological Trace Element Research.
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Abdallah H. Fathy, Riyadh Musaed Naji & Mohamed A. Bashandy. (2023) Antioxidant and Hepatoprotective Effects of Fig Fruit Extract with Olive Oil and Date-Palm Fruit Extract on Hepatic Toxicity of Oral Subchronic Exposure to Some Nanoparticles in Wistar Rats. Journal of Food Quality 2023, pages 1-13.
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Ajamaluddin Malik, Javed Masood Khan, Abdullah S. Alhomida, Mohammad Shamsul Ola, Mohammed Abdulkarim Alshehri & Aqeel Ahmad. (2022) Metal nanoparticles: biomedical applications and their molecular mechanisms of toxicity. Chemical Papers 76:10, pages 6073-6095.
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A. Mahalakshmi, S. Ramkumar, S. Vinurajkumar & G. Sasi. Synthesis of ZnO nanoparticles and its characterization techniques using XRD and FTIR. Synthesis of ZnO nanoparticles and its characterization techniques using XRD and FTIR.
Archna Panghal & Swaran Jeet Singh Flora. 2022. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology 323 345 .
Ritesh K Shukla, Ashish Badiye, Kamayani Vajpayee & Neeti Kapoor. (2021) Genotoxic Potential of Nanoparticles: Structural and Functional Modifications in DNA. Frontiers in Genetics 12.
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Hedaiat Moradpoor, Mohsen Safaei, Hamid Reza Mozaffari, Roohollah Sharifi, Mohammad Moslem Imani, Amin Golshah & Negin Bashardoust. (2021) An overview of recent progress in dental applications of zinc oxide nanoparticles. RSC Advances 11:34, pages 21189-21206.
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T.S. Kumaravel, B. Brabu, N. Parthiban, S.S. Murugan & A.N. Jha. (2021) ‘Site of contact genotoxicity’ assessment for implants - Potential use of single cell gel electrophoresis in biocompatibility testing of medical devices. Toxicology Letters 341, pages 59-67.
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Sneh M. Toprani, Dimitrios Bitounis, Qiansheng Huang, Nathalia Oliveira, Kee Woei Ng, Chor Yong Tay, Zachary D. Nagel & Philip Demokritou. (2021) High-Throughput Screening Platform for Nanoparticle-Mediated Alterations of DNA Repair Capacity. ACS Nano 15:3, pages 4728-4746.
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Eşref Demir. (2020) A review on nanotoxicity and nanogenotoxicity of different shapes of nanomaterials. Journal of Applied Toxicology 41:1, pages 118-147.
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Atena Khodabandeh, Rana Yakhchian, Anwarul Hasan, Bilal Ahamad Paray, Farshad Shahi, Behnam Rasti, Mirsasan Mirpour, Majid Sharifi, Hossein Derakhshankhah, Keivan Akhtari, Zhenxia Zhang, Guowei Gong, Yuzhong Zheng & Mojtaba Falahati. (2020) Silybin as a potent inhibitor of a-synuclein aggregation and associated cytotoxicity against neuroblastoma cells induced by zinc oxide nanoparticles. Journal of Molecular Liquids 310, pages 113198.
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Mona G. Amer & Rehab A. Karam. (2018) Morphological and Biochemical Features of Cerebellar Cortex After Exposure to Zinc Oxide Nanoparticles: Possible Protective Role of Curcumin. The Anatomical Record 301:8, pages 1454-1466.
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Giray Buğra Akbaba & Hasan Türkez. (2018) Investigation of the Genotoxicity of Aluminum Oxide, β-Tricalcium Phosphate, and Zinc Oxide Nanoparticles In Vitro. International Journal of Toxicology 37:3, pages 216-222.
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Helena Moratin, Agmal Scherzad, Thomas Gehrke, Pascal Ickrath, Katrin Radeloff, Norbert Kleinsasser & Stephan Hackenberg. (2018) Toxicological characterization of ZnO nanoparticles in malignant and non-malignant cells. Environmental and Molecular Mutagenesis 59:3, pages 247-259.
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Thomas Schneider, Martin Westermann & Michael Glei. (2017) In vitro uptake and toxicity studies of metal nanoparticles and metal oxide nanoparticles in human HT29 cells. Archives of Toxicology 91:11, pages 3517-3527.
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Andrew Collins, Naouale El Yamani & Maria Dusinska. (2017) Sensitive detection of DNA oxidation damage induced by nanomaterials. Free Radical Biology and Medicine 107, pages 69-76.
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Avnika Singh Anand, Dipti N. Prasad, Shashi Bala Singh & Ekta Kohli. (2017) Chronic exposure of zinc oxide nanoparticles causes deviant phenotype in Drosophila melanogaster. Journal of Hazardous Materials 327, pages 180-186.
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Marie Carriere, Sylvie Sauvaigo, Thierry Douki & Jean-Luc Ravanat. (2017) Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses. Mutagenesis 32:1, pages 203-213.
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Qian Liu, Cheng Xu, Guixiang Ji, Hui Liu, Yiqun Mo, David J. Tollerud, Aihua Gu & Qunwei Zhang. (2016) Sublethal effects of zinc oxide nanoparticles on male reproductive cells. Toxicology in Vitro 35, pages 131-138.
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Madalina G. Albu, Todorka G. Vladkova, Iliana A. Ivanova, Ahmed S. A. Shalaby, Veselina S. Moskova-Doumanova, Anna D. Staneva, Yanko B. Dimitriev, Anelya S. Kostadinova & Tanya I. Topouzova-Hristova. (2016) Preparation and Biological Activity of New Collagen Composites, Part I: Collagen/Zinc Titanate Nanocomposites. Applied Biochemistry and Biotechnology 180:1, pages 177-193.
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Joanna Roszak, Julia Catalán, Hilkka Järventaus, Hanna K. Lindberg, Satu Suhonen, Minnamari Vippola, Maciej Stępnik & Hannu Norppa. (2016) Effect of particle size and dispersion status on cytotoxicity and genotoxicity of zinc oxide in human bronchial epithelial cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 805, pages 7-18.
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Chunping Xu, Manuel Ojeda, Rick A. D. Arancon, Antonio A. Romero, José Luis Domingo, Mercedes Gómez, Jordi Blanco & Rafael Luque. (2015) Bioinspired Porous ZnO Nanomaterials from Fungal Polysaccharides: Advanced Materials with Unprecedented Low Toxicity in Vitro for Human Cells . ACS Sustainable Chemistry & Engineering 3:11, pages 2716-2725.
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Mohamed Alaraby, Balasubramanyam Annangi, Alba Hernández, Amadeu Creus & Ricard Marcos. (2015) A comprehensive study of the harmful effects of ZnO nanoparticles using Drosophila melanogaster as an in vivo model. Journal of Hazardous Materials 296, pages 166-174.
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Lina Ghibelli & Sanjay Mathur. (2014) Biological interactions of oxide nanoparticles: The good and the evil. MRS Bulletin 39:11, pages 949-954.
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