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Original Articles

In Vitro Analysis of Early Genotoxic and Cytotoxic Effects of Okadaic Acid in Different Cell Types of the Mussel Mytilus galloprovincialis

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Diego Figueroa, Ailen Signore, Oscar Araneda, Héctor R. Contreras, Miguel Concha & Carlos García. (2020) Toxicity and differential oxidative stress effects on zebrafish larvae following exposure to toxins from the okadaic acid group. Journal of Toxicology and Environmental Health, Part A 83:15-16, pages 573-588.
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Andrew Collins, Peter Møller, Goran Gajski, Soňa Vodenková, Abdulhadi Abdulwahed, Diana Anderson, Ezgi Eyluel Bankoglu, Stefano Bonassi, Elisa Boutet-Robinet, Gunnar Brunborg, Christy Chao, Marcus S. Cooke, Carla Costa, Solange Costa, Alok Dhawan, Joaquin de Lapuente, Cristian Del Bo’, Julien Dubus, Maria Dusinska, Susan J. Duthie, Naouale El Yamani, Bevin Engelward, Isabel Gaivão, Lisa Giovannelli, Roger Godschalk, Sofia Guilherme, Kristine B. Gutzkow, Khaled Habas, Alba Hernández, Oscar Herrero, Marina Isidori, Awadhesh N. Jha, Siegfried Knasmüller, Ingeborg M. Kooter, Gudrun Koppen, Marcin Kruszewski, Carina Ladeira, Blanca Laffon, Marcelo Larramendy, Ludovic Le Hégarat, Angélique Lewies, Anna Lewinska, Guillermo E. Liwszyc, Adela López de Cerain, Mugimane Manjanatha, Ricard Marcos, Mirta Milić, Vanessa Moraes de Andrade, Massimo Moretti, Damian Muruzabal, Matjaž Novak, Rui Oliveira, Ann-Karin Olsen, Norah Owiti, Mário Pacheco, Alok K. Pandey, Stefan Pfuhler, Bertrand Pourrut, Kerstin Reisinger, Emilio Rojas, Elise Rundén-Pran, Julen Sanz-Serrano, Sergey Shaposhnikov, Ville Sipinen, Karen Smeets, Helga Stopper, João Paulo Teixeira, Vanessa Valdiglesias, Mahara Valverde, Frederique van Acker, Frederik-Jan van Schooten, Marie Vasquez, Johannes F. Wentzel, Maciej Wnuk, Annelies Wouters, Bojana Žegura, Tomas Zikmund, Sabine A. S. Langie & Amaya Azqueta. (2023) Measuring DNA modifications with the comet assay: a compendium of protocols. Nature Protocols 18:3, pages 929-989.
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Karsoon Tan, Yizhou Sun, Hongkuan Zhang & Huaiping Zheng. (2023) Effects of harmful algal blooms on the physiological, immunity and resistance to environmental stress of bivalves: Special focus on paralytic shellfish poisoning and diarrhetic shellfish poisoning. Aquaculture 563, pages 739000.
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Christopher J. Coates & Kenneth Söderhäll. (2021) The stress–immunity axis in shellfish. Journal of Invertebrate Pathology 186, pages 107492.
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Jia-hui Huang, Yu-hu Jiao, Li Li, Da-wei Li, Hong-ye Li & Wei-dong Yang. (2021) Small RNA analysis of Perna viridis after exposure to Prorocentrum lima, a DSP toxins-producing dinoflagellate. Aquatic Toxicology 239, pages 105950.
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Norma Estrada, Erick J. Núñez-Vázquez, Alejandra Palacios, Felipe Ascencio, Laura Guzmán-Villanueva & Rubén G. Contreras. (2021) In vitro Evaluation of Programmed Cell Death in the Immune System of Pacific Oyster Crassostrea gigas by the Effect of Marine Toxins. Frontiers in Immunology 12.
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José Carlos Martins, Dany Domínguez-Pérez, Catarina Azevedo, Ana Catarina Braga, Pedro Reis Costa, Hugo Osório, Vitor Vasconcelos & Alexandre Campos. (2020) Molecular Responses of Mussel Mytilus galloprovincialis Associated to Accumulation and Depuration of Marine Biotoxins Okadaic Acid and Dinophysistoxin-1 Revealed by Shotgun Proteomics. Frontiers in Marine Science 7.
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Malwenn Lassudrie, Hélène Hégaret, Gary H. Wikfors & Patricia Mirella da Silva. (2020) Effects of marine harmful algal blooms on bivalve cellular immunity and infectious diseases: A review. Developmental & Comparative Immunology 108, pages 103660.
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Min Dou, Yu-hu Jiao, Jian-wei Zheng, Gong Zhang, Hong-ye Li, Jie-sheng Liu & Wei-dong Yang. (2020) De novo transcriptome analysis of the mussel Perna viridis after exposure to the toxic dinoflagellate Prorocentrum lima. Ecotoxicology and Environmental Safety 192, pages 110265.
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Zheng-bing He, Guo-fang Duan, Cai-ying Liang, Hong-ye Li, Jie-sheng Liu & Wei-dong Yang. (2019) Up-regulation of Nrf2-dependent antioxidant defenses in Perna viridis after exposed to Prorocentrum lima. Fish & Shellfish Immunology 90, pages 173-179.
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Xiao-Meng Wei, Mi-Yu Lu, Guo-Fang Duan, Hong-Ye Li, Jie-Sheng Liu & Wei-Dong Yang. (2019) Responses of CYP450 in the mussel Perna viridis after short-term exposure to the DSP toxins-producing dinoflagellate Prorocentrum lima. Ecotoxicology and Environmental Safety 176, pages 178-185.
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Christopher J. Coates, Jenson Lim, Katie Harman, Andrew F. Rowley, David J. Griffiths, Helena Emery & Will Layton. (2018) The insect, Galleria mellonella, is a compatible model for evaluating the toxicology of okadaic acid. Cell Biology and Toxicology 35:3, pages 219-232.
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Raquel A.F. Neves, Tainá Cristina Santiago, Wanderson F. Carvalho, Edson dos Santos Silva, Patricia Mirella da Silva & Silvia M. Nascimento. (2019) Impacts of the toxic benthic dinoflagellate Prorocentrum lima on the brown mussel Perna perna: Shell-valve closure response, immunology, and histopathology. Marine Environmental Research 146, pages 35-45.
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Ling-ling Fu, Xiao-yu Zhao, Lin-dan Ji & Jin Xu. (2019) Okadaic acid (OA): Toxicity, detection and detoxification. Toxicon 160, pages 1-7.
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Cheng Chi, Sib Giri, Jin Jun, Sang Kim, Hyoun Kim, Jeong Kang & Se Park. (2018) Detoxification- and Immune-Related Transcriptomic Analysis of Gills from Bay Scallops (Argopecten irradians) in Response to Algal Toxin Okadaic Acid. Toxins 10:8, pages 308.
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Eny Kusrini, Fatimah Hashim, Cindy Gunawan, Riti Mann, Wan Nor Nadhirah Wan Noor Azmi & Nakisah Mat Amin. (2018) Anti-amoebic activity of acyclic and cyclic-samarium complexes on Acanthamoeba. Parasitology Research 117:5, pages 1409-1417.
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M.V. Prego-Faraldo, L.R. Vieira, J.M. Eirin-Lopez, J. Méndez & L. Guilhermino. (2017) Transcriptional and biochemical analysis of antioxidant enzymes in the mussel Mytilus galloprovincialis during experimental exposures to the toxic dinoflagellate Prorocentrum lima. Marine Environmental Research 129, pages 304-315.
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Yu-hu Jiao, Min Dou, Guang Wang, Hong-ye Li, Jie-sheng Liu, Xuesong Yang & Wei-dong Yang. (2017) Exposure of okadaic acid alters the angiogenesis in developing chick embryos. Toxicon 133, pages 74-81.
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Rodrigo Gonzalez-Romero, Victoria Suarez-Ulloa, Javier Rodriguez-Casariego, Daniel Garcia-Souto, Gabriel Diaz, Abraham Smith, Juan Jose Pasantes, Gary Rand & Jose M. Eirin-Lopez. (2017) Effects of Florida Red Tides on histone variant expression and DNA methylation in the Eastern oyster Crassostrea virginica. Aquatic Toxicology 186, pages 196-204.
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María Prego-Faraldo, Vanessa Valdiglesias, Blanca Laffon, Josefina Mendez & Jose Eirin-Lopez. (2016) Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis. Toxins 8:6, pages 159.
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Marisa Silva, Inés Rodriguez, Aldo Barreiro, Manfred Kaufmann, Ana Neto, Meryem Hassouani, Brahim Sabour, Amparo Alfonso, Luis Botana & Vitor Vasconcelos. (2015) New Invertebrate Vectors of Okadaic Acid from the North Atlantic Waters—Portugal (Azores and Madeira) and Morocco. Toxins 7:12, pages 5337-5347.
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Victoria Suarez-Ulloa, Juan Fernandez-Tajes, Vanessa Aguiar-Pulido, M. Veronica Prego-Faraldo, Fernanda Florez-Barros, Alexia Sexto-Iglesias, Josefina Mendez & Jose M. Eirin-Lopez. (2015) Unbiased high-throughput characterization of mussel transcriptomic responses to sublethal concentrations of the biotoxin okadaic acid. PeerJ 3, pages e1429.
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