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Original Articles

Polybrominated Diphenyl Ether (PBDE)-Induced Suppression of Phosphoenolpyruvate Carboxykinase (PEPCK) Decreases Hepatic Glyceroneogenesis and Disrupts Hepatic Lipid Homeostasis

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Pages 1437-1449 | Received 11 Aug 2015, Accepted 18 Sep 2015, Published online: 21 Dec 2015

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David C. Dorman, Weihsueh Chiu, Barbara F. Hales, Russ Hauser, Kamin J. Johnson, Ellen Mantus, Susan Martel, Karen A. Robinson, Andrew A. Rooney, Ruthann Rudel, Sheela Sathyanarayana, Susan L. Schantz & Katrina M. Waters. (2018) Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence. Journal of Toxicology and Environmental Health, Part B 21:4, pages 269-289.
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Lilian C Pereira, Alecsandra O Souza, Maria J Tasso, Alana M C Oliveira, Filipe V Duarte, Carlos M Palmeira & Daniel J Dorta. (2017) Exposure to decabromodiphenyl ether (BDE-209) produces mitochondrial dysfunction in rat liver and cell death. Journal of Toxicology and Environmental Health, Part A 80:19-21, pages 1129-1144.
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Articles from other publishers (10)

Yiran Chen, Jiayun Lv, Lei Fu, Yan Wu, Si Zhou, Shiwei Liu, Linjie Zheng, Wenru Feng & Lin Zhang. (2023) Metabolome-wide association study of four groups of persistent organic pollutants and abnormal blood lipids. Environment International 173, pages 107817.
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Kei Nomiyama, Yasuo Yamamoto, Akifumi Eguchi, Hiroyuki Nishikawa, Hazuki Mizukawa, Nozomu Yokoyama, Osamu Ichii, Mitsuyoshi Takiguchi, Shouta M.M. Nakayama, Yoshinori Ikenaka & Mayumi Ishizuka. (2022) Health impact assessment of pet cats caused by organohalogen contaminants by serum metabolomics and thyroid hormone analysis. Science of The Total Environment 842, pages 156490.
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Zifan Wang, Cuilin Zhang, Paige L. Williams, Andrea Bellavia, Blair J. Wylie, Michele R. Hacker, Kurunthachalam Kannan, Michael S. Bloom, Kelly J. Hunt, Russ Hauser & Tamarra James-Todd. (2022) Polybrominated diphenyl ethers in early pregnancy and preterm birth: Findings from the NICHD Fetal Growth Studies. International Journal of Hygiene and Environmental Health 243, pages 113978.
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Svenja Neumann, Mikael Harju, Dorte Herzke, Tycho Anker-Nilssen, Signe Christensen-Dalsgaard, Magdalene Langset & Geir Wing Gabrielsen. (2021) Ingested plastics in northern fulmars (Fulmarus glacialis): A pathway for polybrominated diphenyl ether (PBDE) exposure?. Science of The Total Environment 778, pages 146313.
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Yupeng Zhu, Li Jing, Xiangyang Li, Dan Zheng, Guiqing Zhou, Yue Zhang, Yujian Sang, Zhixiong Shi, Zhiwei Sun & Xianqing Zhou. (2021) Decabromodiphenyl ether disturbs hepatic glycolipid metabolism by regulating the PI3K/AKT/GLUT4 and mTOR/PPARγ/RXRα pathway in mice and L02 cells. Science of The Total Environment 763, pages 142936.
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Angela Zhang, Cindy Yanfei Li, Edward J. Kelly, Lianne Sheppard & Julia Yue Cui. (2020) Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA- PCG pairs involved in intermediary metabolism. PLOS ONE 15:2, pages e0224644.
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David K. Scoville, Cindy Yanfei Li, Dongfang Wang, Joseph L. Dempsey, Daniel Raftery, Sridhar Mani, Haiwei Gu & Julia Yue Cui. (2019) Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome–Related Aqueous Metabolites in Mice. Drug Metabolism and Disposition 47:8, pages 928-940.
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Venu Seenappa, Manjunath B. Joshi & Kapaettu Satyamoorthy. (2019) Intricate Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Isoforms in Normal Physiology and Disease. Current Molecular Medicine 19:4, pages 247-272.
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Xin Liu, Lei Zhang, Jingguang Li, Guimin Meng, Min Chi, Tiantian Li, Yunfeng Zhao & Yongning Wu. (2018) A nested case-control study of the association between exposure to polybrominated diphenyl ethers and the risk of gestational diabetes mellitus. Environment International 119, pages 232-238.
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Ahmed Khalil, Mikhail Parker, Richard Mpanga, Sebnem E. Cevik, Cassandra Thorburn & Alexander Suvorov. (2017) Developmental Exposure to 2,2′,4,4′–Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice. Journal of the Endocrine Society 1:4, pages 323-344.
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