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Journal of Toxicology and Environmental Health, Part A
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Volume 82, 2019 - Issue 5
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Articles

Inhibitory effects of protopanaxatriol type ginsenoside fraction (Rgx365) on particulate matter-induced pulmonary injury

Wonhwa LeeAging Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Deajeon, Republic of Korea;College of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics based Creative Drug Research Team, Kyungpook National University, Daegu, Republic of KoreaView further author information
,
Sae-Kwang KuDepartment of Histology and Anatomy, College of Korean Medicine, Daegu Haany University, Gyeongsan-si, Republic of KoreaView further author information
,
Ji-Eun KimCollege of Pharmacy, Chungnam National University, Daejon, Republic of KoreaView further author information
,
Soo-Hyun ChoCollege of Pharmacy, Chungnam National University, Daejon, Republic of KoreaView further author information
,
Gyu-Yong SongCollege of Pharmacy, Chungnam National University, Daejon, Republic of KoreaCorrespondence[email protected]
View further author information
&
Jong-Sup BaeCollege of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics based Creative Drug Research Team, Kyungpook National University, Daegu, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5756-9367View further author information
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Pages 338-350 | Published online: 27 Mar 2019

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Katharina Kappler, Torsten Grothe, Shalini Srivastava & Manjiri Jagtap. (2022) Evaluation of the Efficacy and Safety of Blue Fenugreek Kale Extract on Skin Health and Aging: In-vitro and Clinical Evidences. Clinical, Cosmetic and Investigational Dermatology 15, pages 2051-2064.
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Da Hye Kim, Hyesook Lee, Hyun Hwangbo, So Young Kim, Seon Yeong Ji, Min Yeong Kim, Seh-Kwang Park, Sung-Ho Park, Mi-Young Kim, Gi-Young Kim, Jaehun Cheong, Soo-Wan Nam & Yung Hyun Choi. (2022) Particulate matter 2.5 promotes inflammation and cellular dysfunction via reactive oxygen species/p38 MAPK pathway in primary rat corneal epithelial cells. Cutaneous and Ocular Toxicology 41:4, pages 273-284.
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Gi Ho Lee, Sun Woo Jin, Jae Ho Choi, Eun Hee Han, Yong Pil Hwang, Chul Yung Choi & Hye Gwang Jeong. (2021) Influence of o,p′-DDT on MUC5AC expression via regulation of NF-κB/AP-1 activation in human lung epithelial cells. Journal of Toxicology and Environmental Health, Part A 84:20, pages 836-845.
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Jin Ju Park, Junmin An, Jung Dae Lee, Hyang Yeon Kim, Jueng Eun Im, Eunyoung Lee, Jaehyoun Ha, Chang Hui Cho, Dong-Wan Seo & Kyu-Bong Kim. (2020) Effects of anti-wrinkle and skin-whitening fermented black ginseng on human subjects and underlying mechanism of action. Journal of Toxicology and Environmental Health, Part A 83:11-12, pages 470-484.
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Jin Ju Park, Junmin An, Jung Dae Lee, Hyang Yeon Kim, Jueng Eun Im, Eunyoung Lee, Jaehyoun Ha, Chang Hui Cho, Dong-Wan Seo & Kyu-Bong Kim. (2020) Effects of anti-wrinkle and skin-whitening fermented black ginseng on human subjects and underlying mechanism of action. Journal of Toxicology and Environmental Health, Part A 83:11-12, pages 423-437.
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Yong Chan Kwon, Hyung Sik Kim & Byung-Mu Lee. (2020) Detoxifying effects of optimal hyperoxia (40% oxygenation) exposure on benzo[a]pyrene-induced toxicity in human keratinocytes. Journal of Toxicology and Environmental Health, Part A 83:2, pages 82-94.
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Articles from other publishers (14)

Hye-Jin Lee, Hui-Ji Choi, Sang-Ah Lee, Dong Hyuk Baek, Jong Beom Heo, Gyu Yong Song & Wonhwa Lee. (2023) Myogenesis Effects of RGX365 to Improve Skeletal Muscle Atrophy. Nutrients 15:19, pages 4307.
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Mi-Ran Kim, Jin-Hwa Lee, Mo-Un Ku, Ki-Young Kim, Su Shin, Eun-Jin Hong, Sae-Kwang Ku & Jae-Suk Choi. (2023) Effectiveness of Immature Asian Pear Extract on Pulmonary Injury Caused by Particulate Matter in Mice. Applied Sciences 13:17, pages 9578.
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Bertoka Fajar Surya Perwira Negara, Joo Wan Kim, Khawaja Muhammad Imran Bashir, Jin-Hwa Lee, Mo-Un Ku, Ki-Young Kim, Su Shin, Eun-Jin Hong, Sae-Kwang Ku & Jae-Suk Choi. (2023) Expectorant Effects of Immature Asian Pear Extract on PM2.5-Induced Subacute Pulmonary Injury in Mice. Journal of Food Biochemistry 2023, pages 1-19.
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Lu Ding, Hongyu Qi, Yisa Wang, Zepeng Zhang, Qing Liu, Chen Guo, Jiaqi Liu, Zhaoqiang Chen, Jing Li, JinJin Chen, Qingxia Huang, Daqing Zhao, Zeyu Wang & Xiangyan Li. (2023) Recent advances in ginsenosides against respiratory diseases: Therapeutic targets and potential mechanisms. Biomedicine & Pharmacotherapy 158, pages 114096.
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Cuizhu Wang, Luying Tan, Juntong Liu, Dongxing Fu, Caixia Wang, Pingya Li, Zhuo Li & Jinping Liu. (2022) Integrated Metabolomics and Network Pharmacology to Decipher the Latent Mechanisms of Protopanaxatriol against Acetic Acid-Induced Gastric Ulcer. International Journal of Molecular Sciences 23:20, pages 12097.
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Seok-Man Park, Cheol-Jong Jung, Dae-Geon Lee, Beom-Rak Choi, Tae-Hun Ku, Im-Joung La, Il-Je Cho & Sae-Kwang Ku. (2022) Adenophora Stricta Root Extract Protects Lung Injury from Exposure to Particulate Matter 2.5 in Mice. Antioxidants 11:7, pages 1376.
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Xi Yang, Jia You, Yuanfeng Wei, Huawei Li, Ling Gao, Qing Guo, Ying Huang, Changyang Gong & Cheng Yi. (2021) Emerging nanomaterials applied for tackling the COVID-19 cytokine storm. Journal of Materials Chemistry B 9:39, pages 8185-8201.
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Wenhua Yang, Jianli Zhou, Jean Damascene Harindintwali & Xiaobin Yu. (2021) Production of minor ginsenosides by combining Stereum hirsutum and cellulase. PLOS ONE 16:8, pages e0255899.
Crossref
Hee Ho Park, Hyelim Kim, Han Sol Lee, Eun U Seo, Ji-Eun Kim, Jee-Hyun Lee, Yong-Hyeon Mun, So-Yeol Yoo, Jiseon An, Mi-Young Yun, Nae-Won Kang, Dae-Duk Kim, Dong Hee Na, Kyung Soo Hong, Jong Geol Jang, June Hong Ahn, Jong-Sup Bae, Gyu Yong Song, Jae-Young Lee, Hong Nam Kim & Wonhwa Lee. (2021) PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses. Biomaterials 273, pages 120827.
Crossref
Hye-Ji Lee & Hye-Jin Park. (2021) Germinated Rhynchosia nulubilis Fermented with Lactobacillus pentosus SC65 Reduces Particulate Matter Induced Type II Alveolar Epithelial Apoptotic Cell Death. International Journal of Molecular Sciences 22:7, pages 3660.
Crossref
Wonhwa Lee, Dongyup Hahn, Hyunchae Sim, Samyeol Choo, Sangkyu Lee, Taeho Lee & Jong-Sup Bae. (2020) Inhibitory functions of cardamonin against particulate matter-induced lung injury through TLR2,4-mTOR-autophagy pathways. Fitoterapia 146, pages 104724.
Crossref
So Yeon Jeong, Jaehong Kim, Eui Kyun Park, Moon-Chang Baek & Jong-Sup Bae. (2020) Inhibitory functions of maslinic acid on particulate matter-induced lung injury through TLR4-mTOR-autophagy pathways. Environmental Research 183, pages 109230.
Crossref
Si-Ling Chen, Zhi-Wen Li, Shao-Ming Chi, Hui-Wen Yang, Yun-Yun Zhang, Yu-Fei Wang, Hong-You Zhu & Yan Zhao. (2020) Preparation, characterization and solubilization evaluation of two novel host-guest complexes based on two different functional groups of modified β-cyclodextrins and 20(S)-protopanaxatriol. Journal of Molecular Structure 1204, pages 127494.
Crossref
So Yeon Jeong, Ji-Eun Kim, Gyu-Yong Song & Jong-Sup Bae. (2020) Rgx365, a Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-κB. The American Journal of Chinese Medicine 48:05, pages 1091-1102.
Crossref

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