Advanced search
Publication Cover
Journal of Toxicology and Environmental Health Volume 5, 1979 - Issue 1: NCTR/NCI Symposium on the Use of Inbred and Ootbred Animals in Toxicological Testing
Journal homepage
1
Views
15
CrossRef citations to date
0
Altmetric
Session 4: Genetics and statistical aspects of toxicological testing: Chairperson: David W. Gaylor, National Center for Toxicological Research

Statistical design of toxicity assays: Role of genetic structure of test animal population

J. K. Haseman Biometry Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, 27709
&
D. G. Hoel Biometry Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
Pages 89-101 | Published online: 19 Oct 2009

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

GeorgeL. Wolff, DavidW. Gaylor, Boon‐Nam Blackwell & GaryE. Moore. (1991) Bladder and liver tumorigenesis induced by 2‐acetylaminofluorene in different F1 mouse hybrids: Variation within genotypes and effects of using more than one genotype on risk assessment. Journal of Toxicology and Environmental Health 33:3, pages 327-348.
Read now
Robert Paul Felton & DavidW. Gaylor. (1989) Multistrain experiments for screening toxic substances. Journal of Toxicology and Environmental Health 26:4, pages 399-411.
Read now
Michael F. W. Festing & Elliot S. Vesell. (1987) Genetic Factors in Toxicology: Implications for Toxicological Screening. CRC Critical Reviews in Toxicology 18:1, pages 1-26.
Read now
MichaelF. W. Festing. (1979) Properties of inbred strains and outbred stocks, with special reference to toxicity testing. Journal of Toxicology and Environmental Health 5:1, pages 53-68.
Read now

Articles from other publishers (11)

Michael F. W. Festing. (2010) Inbred Strains Should Replace Outbred Stocks in Toxicology, Safety Testing, and Drug Development. Toxicologic Pathology 38:5, pages 681-690.
Crossref
Werner K. Lutz, Roman W. Lutz & Melvin E. Andersen. (2006) Dose-Incidence Relationships Derived from Superposition of Distributions of Individual Susceptibility on Mechanism-Based Dose Responses for Biological Effects. Toxicological Sciences 90:1, pages 33-38.
Crossref
Ruth Chia, Francesca Achilli, Michael F W Festing & Elizabeth M C Fisher. (2005) The origins and uses of mouse outbred stocks. Nature Genetics 37:11, pages 1181-1186.
Crossref
Shayne Gad. 2005. Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition. Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition 241 280 .
M F Festing. (1995) Use of a multistrain assay could improve the NTP carcinogenesis bioassay.. Environmental Health Perspectives 103:1, pages 44-52.
Crossref
. 1991. Evaluation of Environmental Data for Regulatory and Impact Assessment. Evaluation of Environmental Data for Regulatory and Impact Assessment 363 419 .
I. Ralph Edwards, Donald G. Ferry & Wayne A. Temple. 1991. Classes of Pesticides. Classes of Pesticides 1409 1470 .
Daniel Krewski & Michael Goddard. (2016) Principles of Bioassay Design. Drug Information Journal 24:2, pages 381-394.
Crossref
D.P. Lovell, D. Anderson & P.C. Jenkinson. (1987) The use of a battery of strains of mice in a factorial design to study the induction of dominant lethal mutations. Mutation Research/Genetic Toxicology 187:1, pages 37-44.
Crossref
L.G. Hart, J.E. Huff, J.A. Moore & D.P. Rall. 1983. Hazard Assessment of Chemicals. Hazard Assessment of Chemicals 191 244 .
I.C. Munro & D.R. Krewski. (1981) Risk assessment and regulatory decision making. Food and Cosmetics Toxicology 19, pages 549-560.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.