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Inger Varnbo, Anders Peterson & Erik Walum. (1985) Effects of toxic chemicals on the respiratory activity of cultured mouse neuroblastoma cells. Xenobiotica 15:8-9, pages 727-733.
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Daniela Nedelcheva, Stoyanka Stoeva, Sabcho Dimitrov, Ann Detroyer, Aziz Fadli, Reine Note, Delphine Blanchet & Ovanes Mekenyan. (2019) In silico mechanistically-based profiling module for acute oral toxicity. Computational Toxicology 12, pages 100109.
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Anna Forsby, Lisbeth E. Knudsen & Hanna Tähti. 2019. The History of Alternative Test Methods in Toxicology. The History of Alternative Test Methods in Toxicology
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Björn Ekwall, Frank A. Barile, Argelia Castano, Cecilia Clemedson, Richard H. Clothier, Paul Dierickx, Barbro Ekwall, Margherita Ferro, Geirid Fiskesjö, Lourdes Garza-Ocañas, Maria José Gómez-Lechón, Michael Gülden, Tony Hall, Boris Isomaa, Anne Kahru, Gustaw Kerszman, Udo Kristen, Manabu Kunimoto, Sirpa Kärenlampi, Lillemor Lewan, Anatoly Loukianov, Tadao Ohno, Guido Persoone, Lennart Romert, Thomas W. Sawyer, Ravi Shrivastava, Helmut Segner, Annalaura Stammati, Noriho Tanaka, Matteo Valentino, Erik Walum & Flavia Zucco. (2020) MEIC Evaluation of Acute Systemic Toxicity. Alternatives to Laboratory Animals 26:2_suppl, pages 617-658.
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E Walum. (1998) Acute oral toxicity.. Environmental Health Perspectives 106:suppl 2, pages 497-503.
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G J Harry, M Billingsley, A Bruinink, I L Campbell, W Classen, D C Dorman, C Galli, D Ray, R A Smith & H A Tilson. (1998) In vitro techniques for the assessment of neurotoxicity.. Environmental Health Perspectives 106:suppl 1, pages 131-158.
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Stefan Fennrich, Heike Stier, Karl-Josef F�hr, David Ray, Jean-Fran�ois Ghersi-Egea & Burkhard Schlosshauer. (1996) Organotypic rat brain culture as in vivo-like model system. Methods in Cell Science 18:4, pages 283-291.
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Erik Walum, Anna Forsby, Cecilia Clemedson & Björn Ekwall. (2020)
Dynamic Qualities of Validation and the Evolution of New
In Vitro
Toxicological Tests
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M.J. Garle, J.H. Fentem & J.R. Fry. (1994) In vitro cytotoxicity tests for the prediction of acute toxicity in vivo. Toxicology in Vitro 8:6, pages 1303-1312.
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L. Odland, L. Romert, C. Clemedson & E. Walum. (1994) Glutathione content, glutathione transferase activity and lipid peroxidation in acrylamide-treated neuroblastoma N1E 115 cells. Toxicology in Vitro 8:2, pages 263-267.
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Oliver Flint. 1994. Alternatives to Animal Testing. Alternatives to Animal Testing
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M.C. Calleja, G. Persoone & P. Geladi. (1994) Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties. Food and Chemical Toxicology 32:2, pages 173-187.
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Mabel C. Calleja, Guido Persoone & Paul Geladi. (2020) The Predictive Potential of a Battery of Ecotoxicological Tests for Human Acute Toxicity, as Evaluated with the First 50 MEIC Chemicals. Alternatives to Laboratory Animals 21:3, pages 330-349.
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M. Gülden. (1993) In vitro toxicity screening using cultured rat skeletal muscle cells. I. Surfactants and mitochondrial poisons. Toxicology in Vitro 7:1, pages 25-34.
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Michael Balls & Julia H. Fentem. (2020) The Use of Basal Cytotoxicity and Target Organ Toxicity Tests in Hazard Identification and Risk Assessment. Alternatives to Laboratory Animals 20:3, pages 368-388.
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F. Villena, G. Montoya, R. Klaasen, R. Fleckenstein & M. Suwalsky. (1992) Morphological changes on nerves and histopathological effects on liver and kidney of rats by pentachlorophenol (PCP). Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 101:2, pages 353-363.
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Willi Halle & Horst Spielmann. (2020) Two Procedures for the Prediction of Acute Toxicity (LD50) from Cytotoxicity Data. Alternatives to Laboratory Animals 20:1, pages 40-49.
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Meredith Halks-Miller, Veronica Fedor & Charles A. Tyson. (2016) Overview of Approaches to In Vitro Neurotoxicity Testing. Journal of the American College of Toxicology 10:6, pages 727-736.
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Tanii Hideji & Hashimoto Kazuo. (1991) In vitro neurotoxicity study with dorsal root ganglia for acrylamide and its derivatives. Toxicology Letters 58:2, pages 209-213.
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Willi Halle, Ingo Baeger, Björn Ekwall & Horst Spielmann. (2020)
Correlation between
In Vitro
Cytotoxicity and Octanol/Water Partition Coefficient of 29 Substances from the MEIC Programme
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Björn Ekwall, Inger Bondesson, Sven Hellberg, Johan Högberg, Lennart Romert, Kjell Stenberg & Erik Walum. (2020)
Validation of
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Edward U. Maduh, Joseph L. Borowitz & Gary E. Isom. (2006) Cyanide‐induced alteration of the adenylate energy pool in a rat neurosecretory cell line. Journal of Applied Toxicology 11:2, pages 97-101.
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J.C. Phillips, W.B. Gibson, J. Yam, C.L. Alden & G.C. Hard. (1990) Survey of the QSAR and in vitro approaches for developing non-animal methods to supersede the in vivo LD50 test. Food and Chemical Toxicology 28:5, pages 375-394.
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Inger Bondesson, Björn Ekwall, Sven Hellberg, Lennart Romert, Kjell Stenberg & Erik Walum. (1989) MEIC—A new international multicenter project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests. Cell Biology and Toxicology 5:3, pages 331-347.
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Björn Ekwall & Karl Ekwall. (2020) Comments on the Use of Diverse Cell Systems in Toxicity Testing. Alternatives to Laboratory Animals 15:3, pages 193-201.
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E. Walum. (2020) A Comparison of Different Endpoints in Neuroblastoma Cell Toxicity Tests of Three Heavy Metal Compounds. Alternatives to Laboratory Animals 14:3, pages 164-166.
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S.M. Hunt, C. Chrzanowska, C.R. Barnett & J.K. Fawell. (2020)
The Application of
In Vitro
Cytotoxicity Assays to the Water Industry
. Alternatives to Laboratory Animals 14:2, pages 64-71.
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P. TACHON, J. COTOVIO, K. G. DOSSOUy & M. PRUNIERAS. (2007) Alternative method for checking toxicity of hair dyes. International Journal of Cosmetic Science 8:6, pages 265-273.
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E. Walum, I. Varnbo & A. Peterson. (1986) A multiple cell-culture toxicity test system based on neuroblastoma C1300 cells and differentiated primary cultures of brain, muscle, heart and liver cells. Food and Chemical Toxicology 24:6-7, pages 567-568.
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H. Babich, J. A. Puerner & E. Borenfreund. (1986) In vitro cytotoxicity of metals to bluegill (BF-2) cells. Archives of Environmental Contamination and Toxicology 15:1, pages 31-37.
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Vibeke Bernson, Jørgen Clausen, Björn Ekwall, Arne Hensten-Pettersen, Jørn Holme, Johan Högberg, Mikko Niemi & Erik Walum. (2020) Trends in Scandinavian Cell Toxicology. Alternatives to Laboratory Animals 13:3, pages 162-179.
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