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Journal of Toxicology and Environmental Health Volume 13, 1984 - Issue 4-6
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Original Articles

Haloacetonitrile excretion as thiocyanate and inhibition of dimethylnitrosamine demethylase: A proposed metabolic scheme

Michael A. Pereira U.S. Environmental Protection Agency, Health Effects Research Laboratory, 26 West St. Clair Street, Cincinnati, Ohio, 45268
,
Luan‐Ho C. Lin U.S. Environmental Protection Agency, Health Effects Research Laboratory, Cincinnati, Ohio
&
Joan K. Mattox U.S. Environmental Protection Agency, Health Effects Research Laboratory, Cincinnati, Ohio
Pages 633-641 | Received 04 Aug 1983, Accepted 12 Oct 1983, Published online: 20 Oct 2009

Citations (17)

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J.M. Mathews, D. Pulliam$suffix/text()$suffix/text(), S.R. Black & L.T. Burka. (2010) Metabolism and disposition of [14C]dibromoacetonitrile in rats and mice following oral and intravenous administration. Xenobiotica 40:7, pages 499-509.
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RichardJ. Bull, Glenn Rice & LindaK. Teuschler. (2009) Determinants of Whether or Not Mixtures of Disinfection By-Products are Similar. Journal of Toxicology and Environmental Health, Part A 72:7, pages 437-460.
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SuzanneA. Christ, EleanorJ. Read, JudyA. Stober & M. Kate Smith. (1995) The developmental toxicity of bromochloroacetonitrile in pregnant long‐evans rats. International Journal of Environmental Health Research 5:2, pages 175-188.
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Articles from other publishers (14)

Thomas Caspari, James Dyer, Nathalie Fenner, Christian Dunn & Chris Freeman. (2017) The drinking water contaminant dibromoacetonitrile delays G1-S transition and suppresses Chk1 activation at broken replication forks. Scientific Reports 7:1.
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Richard J. Bull. 2009. Environmental Toxicants. Environmental Toxicants 121 196 .
John C. Lipscomb, Ebtehal El-Demerdash & Ahmed E. Ahmed. 2009. Reviews of Environmental Contamination and Toxicology Volume 198. Reviews of Environmental Contamination and Toxicology Volume 198 1 32 .
Mark G. Muellner, Elizabeth D. Wagner, Kristin McCalla, Susan D. Richardson, Yin-Tak Woo & Michael J. Plewa. (2006) Haloacetonitriles vs. Regulated Haloacetic Acids:  Are Nitrogen-Containing DBPs More Toxic?. Environmental Science & Technology 41:2, pages 645-651.
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R Poon, I Chu, G LeBel, A Yagminas & V.E Valli. (2003) Effects of dibromoacetonitrile on rats following 13-week drinking water exposure. Food and Chemical Toxicology 41:8, pages 1051-1061.
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Ahmed M. Mohamadin. (2001) Possible role of hydroxyl radicals in the oxidation of dichloroacetonitrile by Fenton-like reaction. Journal of Inorganic Biochemistry 84:1-2, pages 97-105.
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. (1994) Appendix H: Chlorinated nitrogen chemicals. Regulatory Toxicology and Pharmacology 20:1, pages S939-S950.
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Ahmed E. Ahmed, Gamal I. Hussein, Jiann‐Ping Loh & Sherif Z. Abdel‐Rahman. (2006) Studies on the mechanism of haloacetonitrile‐induced gastrointestinal toxicity: Interaction of dibromoacetonitrile with glutathione and glutathione‐ S ‐transferase in rats . Journal of Biochemical Toxicology 6:2, pages 115-121.
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Edith L.C. Lin & Charles W. Guion. (1989) Interaction of haloacetonitriles with glutathione and glutathione-S-transferase. Biochemical Pharmacology 38:4, pages 685-688.
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M. K. Smith, J. L. Randall, D. R. Tocco, R. G. York, J. A. Stober & E. J. Read. (2005) Teratogenic effects of trichloroacetonitrile in the long‐evans rat. Teratology 38:2, pages 113-120.
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E L Lin, F B Daniel, S L Herren-Freund & M A Pereira. (1986) Haloacetonitriles: metabolism, genotoxicity, and tumor-initiating activity.. Environmental Health Perspectives 69, pages 67-71.
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M R Roby, S Carle, M A Pereira & D E Carter. (1986) Excretion and tissue disposition of dichloroacetonitrile in rats and mice.. Environmental Health Perspectives 69, pages 215-220.
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J R Hayes, L W CondieJrJr & J F Borzelleca. (1986) Toxicology of haloacetonitriles.. Environmental Health Perspectives 69, pages 183-202.
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M K Smith, H Zenick & E L George. (1986) Reproductive toxicology of disinfection by-products.. Environmental Health Perspectives 69, pages 177-182.
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