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Original Articles

Formation of DNA‐damaging nitroso compounds by interaction of drugs with nitrite. A preliminary screening for detecting potentially hazardous drugs

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Pages 1-24 | Received 04 Jun 1984, Accepted 07 Aug 1984, Published online: 15 Oct 2009

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Monika Lazarová, Juraj Lábaj, Peter Eckl, Grigorij Kogan & Darina Slameňová. (2006) Effects of Dietary Intake of a Fungal β-D-Glucan Derivative on the Level of DNA Damage Induced in Primary Rat Hepatocytes by Various Carcinogens. Nutrition and Cancer 56:1, pages 113-122.
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Darina Slamenova, Ivan Chalupa, Sona Robichova, Alena Gabelova, Timea Farkasova, L'ubica Hrusovska, Gabriela Bacova, Livia Sebova, Peter Eckl, Nikolaus Bresgen, Peter Zeitheim, Peter Schneider, Ladislava Wsolova, Magdalena Barancokova, Alena Kazimirova, Jana Navarova & Stefan Bezek. (2002) Effect of Dietary Intake of Vitamin A or E on the Level of DNA Damage, Chromosomal Aberrations, and Micronuclei Induced in Freshly Isolated Rat Hepatocytes by Different Carcinogens. Nutrition and Cancer 42:1, pages 117-124.
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Articles from other publishers (16)

Stephen Horne, Matthew D. Vera, Laxma R. Nagavelli, Vilayat A. Sayeed, Laurel Heckman, Deborah Johnson, Dan Berger, Yean Yean Yip, Carolina Lopes Krahn, Leticia Oyamada Sizukusa, Nayrton Flavio Moura Rocha, Robert N. Bream, Joachim Ludwig, David A. Keire & Gary Condran. (2023) Regulatory Experiences with Root Causes and Risk Factors for Nitrosamine Impurities in Pharmaceuticals. Journal of Pharmaceutical Sciences 112:5, pages 1166-1182.
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Jean D. Brender. 2015. Handbook of Fertility. Handbook of Fertility 61 74 .
Jean D. Brender, Martha M. Werler, Mayura U. Shinde, Ann M. Vuong, Katherine E. Kelley, John C. HuberJr.Jr., Joseph R. Sharkey, John S. Griesenbeck, Paul A. Romitti, Sadia Malik, Lucina Suarez, Peter H. Langlois & Mark A. Canfield,. (2012) Nitrosatable drug exposure during the first trimester of pregnancy and selected congenital malformations. Birth Defects Research Part A: Clinical and Molecular Teratology 94:9, pages 701-713.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 34 .
Jean D. Brender, Martha M. Werler, Katherine E. Kelley, Ann M. Vuong, Mayura U. Shinde, Qi Zheng, John C. HuberJrJr, Joseph R. Sharkey, John S. Griesenbeck, Paul A. Romitti, Peter H. Langlois, Lucina Suarez & Mark A. Canfield. (2011) Nitrosatable Drug Exposure During Early Pregnancy and Neural Tube Defects in Offspring. American Journal of Epidemiology 174:11, pages 1286-1295.
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Jean D. Brender, Katherine E. Kelley, Martha M. Werler, Peter H. Langlois, Lucina Suarez & Mark A. Canfield. (2011) Prevalence and patterns of nitrosatable drug use among U.S. women during early pregnancy. Birth Defects Research Part A: Clinical and Molecular Teratology 91:4, pages 258-264.
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Giovanni Brambilla & Antonietta Martelli. (2007) Genotoxic and carcinogenic risk to humans of drug–nitrite interaction products. Mutation Research/Reviews in Mutation Research 635:1, pages 17-52.
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Monika Lazarová, Juraj Lábaj, Peter Eckl & Darina Slameňová. (2006) Comparative evaluation of DNA damage by genotoxicants in primary rat cells applying the comet assay. Toxicology Letters 164:1, pages 54-62.
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Giovanni Brambilla & Antonietta Martelli. (2005) Keynote comment: nitrosatable drugs, cancer, and guidelines for genotoxicity. The Lancet Oncology 6:8, pages 538-539.
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Soňa Robichová, Darina Slameňová, Alena Gábelová, Ján Sedlák & Jana Jakubı́ková. (2004) An investigation of the genotoxic effects of N -nitrosomorpholine in mammalian cells. Chemico-Biological Interactions 148:3, pages 163-171.
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Soňa Robichová, Darina Slameňová, Ivan Chalupa & Lı́via Šebová. (2004) DNA lesions and cytogenetic changes induced by N-nitrosomorpholine in HepG2, V79 and VH10 cells: the protective effects of Vitamins A, C and E. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 560:2, pages 91-99.
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Jean D. Brender, Janus M. Olive, Marilyn Felkner, Lucina Suarez, Wendy Marckwardt & Katherine A. Hendricks. (2004) Dietary Nitrites and Nitrates, Nitrosatable Drugs, and Neural Tube Defects. Epidemiology 15:3, pages 330-336.
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Soňa Robichová & Darina Slameňová. (2002) Effects of vitamins C and E on cytotoxicity induced by N-nitroso compounds, N-nitrosomorpholine and N-methyl-N′-nitro-N-nitrosoguanidine in Caco-2 and V79 cell lines.. Cancer Letters 182:1, pages 11-18.
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Elmar Gocke. (1996) Review of the genotoxic properties of chlorpromazine and related phenothiazines. Mutation Research/Reviews in Genetic Toxicology 366:1, pages 9-21.
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Giovanni Brambilla, Luigi Robbiano, Antonietta Martelli, Enrica Cajelli, Alessandra Allavena & Mauro Mazzei. (1989) Genotoxicity of N-nitrosochlordiazepoxide in cultured mammalian cells. Toxicology and Applied Pharmacology 97:3, pages 480-488.
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Johann W. Faigle, Hans Blattner, Hansruedi Glatt, Hans‐Peter Kriemler, Hans Mory, Angelo Storni, Tammo Winkler & Franz Oesch. (2004) Structures and Mutagenic Properties of Products Obtained by C ‐Nitrosation of Opipramol . Helvetica Chimica Acta 70:5, pages 1296-1301.
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