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Original Articles

In vivo percutaneous absorption and decontamination of pesticides in humans

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Pages 25-37 | Received 17 Dec 1984, Accepted 22 Apr 1985, Published online: 20 Oct 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (19)

Thomas James, Lydia Izon-Cooper, Samuel Collins, Haydn Cole & Tim Marczylo. (2022) The wash-in effect and its significance for mass casualty decontamination. Journal of Toxicology and Environmental Health, Part B 25:3, pages 113-134.
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Aileen M. Feschuk, Nadia Kashetsky, Chavy Chiang, Anuk Burli, Halie Burdick & Howard I. Maibach. (2022) Regional variation in percutaneous absorption in in vitro human models: a systematic review. Journal of Toxicology and Environmental Health, Part B 25:3, pages 97-112.
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Chavy Chiang, Nadia Kashetsky, Aileen Feschuk, Anuk Burli, Rebecca Law & Howard Maibach. (2021) Efficacy of water-based skin decontamination of occupational chemicals using in vitro human skin models: a systematic review. Journal of Toxicology and Environmental Health, Part B 24:7, pages 337-353.
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Nicole C. Rouse & Howard I. Maibach. (2016) The effect of volatility on percutaneous absorption. Journal of Dermatological Treatment 27:1, pages 5-10.
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Gayatri Sankaran, Li Chen, Zhenshan Chen, Yu Liu, Terry Lopez, John Ross, Sajleen Phagura, David A. Eastmond & Robert I. Krieger. (2015) The Importance of Hand Exposures to Absorbed Dosage of Hand Harvesters. Journal of Toxicology and Environmental Health, Part A 78:21-22, pages 1369-1383.
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Matthew A. Miller & Gerald B. Kasting. (2009) Toward a Better Understanding of Pesticide Dermal Absorption: Diffusion Model Analysis of Parathion Absorption in Vitro and in Vivo . Journal of Toxicology and Environmental Health, Part A 73:4, pages 284-300.
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RichardP. Moody, Mohammed Akram, Eva Dickson & Ih Chu. (2007) In Vitro Dermal Absorption of Methyl Salicylate, Ethyl Parathion, and Malathion: First Responder Safety. Journal of Toxicology and Environmental Health, Part A 70:12, pages 985-999.
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R. M. Brand, A. R. Charron, V. L. Sandler & J. L. Jendrzejewski. (2007) Moisturizing Lotions can Increase Transdermal Absorption of the Herbicide 2,4-Dichlorophenoxacetic Acid Across Hairless Mouse Skin. Cutaneous and Ocular Toxicology 26:1, pages 15-23.
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J. Scott Boone, John W. Tyler, M. Keith Davis & Janice E. Chambers. (2006) Effects of Topical Phosmet on Fur Residue and Cholinesterase Activity of Dogs. Toxicology Mechanisms and Methods 16:5, pages 275-280.
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James B. Knaak, Curt C. Dary, Fred Power, Carol B. Thompson & Jerry N. Blancato. (2004) Physicochemical and Biological Data for the Development of Predictive Organophosphorus Pesticide QSARs and PBPK/PD Models for Human Risk Assessment. Critical Reviews in Toxicology 34:2, pages 143-207.
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R. M. Brand, M. Spalding & C. Mueller. (2002) Sunscreens Can Increase Dermal Penetration of 2,4-Dichlorophenoxyacetic Acid. Journal of Toxicology: Clinical Toxicology 40:7, pages 827-832.
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RichardP. Moody, RonaldC. Wester, JosephL. Melendres & HowardI. Maibach. (1992) Dermal absorption of the phenoxy herbicide 2,4‐D dimethylamine in humans: Effect of DEET and anatomic site. Journal of Toxicology and Environmental Health 36:3, pages 241-250.
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RonaldC. Wester, HowardI. Maibach, Lena Sedik, Joseph Melendres, ChengL. Liao & Stephen DiZio. (1992) Percutaneous absorption of [14C]chlordane from soil. Journal of Toxicology and Environmental Health 35:4, pages 269-277.
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Jim E. Riviere & Nancy A. Monteiro-Riviere. (1991) The Isolated Perfused Porcine Skin Flap as anIn Vitro Model for Percutaneous Absorption and Cutaneous Toxicology. Critical Reviews in Toxicology 21:5, pages 329-344.
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Omer Pelletier, Leonard Ritter & Joan Caron. (1990) Effects of skin preapplication treatments and postapplication cleansing agents on dermal absorption of 2,4‐dichlorophenoxyacetic acid dimethylamine by Fischer 344 rats. Journal of Toxicology and Environmental Health 31:4, pages 247-260.
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Arik Tabak, Uri Taitelman & Erica Hoffer. (1990) Percutaneous Permeability to Paraqut: In Vitro Experiments with Human Skin. Journal of Toxicology: Cutaneous and Ocular Toxicology 9:4, pages 301-311.
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Omer Pelletier, Leonard Ritter, Joan Caron & Diana Somers. (1989) Disposition of 2,4‐dichlorophenoxyacetic acid dimethylamine salt by fischer 344 rats dosed orally and dermally. Journal of Toxicology and Environmental Health 28:2, pages 221-234.
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Erica Hoffer, Alla Tzipiniuk, Maya Gal & Uri Taitelman. (1989) Skin Versus Blood Distribution of Paraquat in Experimental Animals During Percutaneous Absorption. Journal of Toxicology: Cutaneous and Ocular Toxicology 8:2, pages 179-182.
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Articles from other publishers (73)

Tobias Hundhammer, Regina Lindner, Leopold Caccia, Hannes Langbehn, Walter Petermichl, Michael Dittmar & Michael Gruber. (2023) Management of decontamination in chemical accidents: a laboratory model. Scientific Reports 13:1.
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Le H.D. Do, Rebecca M. Law & Howard I. Maibach. (2022) Dose response effect of chemical surface concentration on percutaneous penetration in human: In vivo + in vitro. Regulatory Toxicology and Pharmacology 132, pages 105186.
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Chavy Chiang, Nadia Kashetsky, Aileen Feschuk, Anuk Burli, Rebecca M. Law & Howard I. Maibach. (2021) Efficacy of water‐only or soap and water skin decontamination of chemical warfare agents or simulants using in vitro human models: A systematic review. Journal of Applied Toxicology 42:6, pages 930-941.
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Nadia Kashetsky, Rebecca M. Law & Howard I. Maibach. (2021) Efficacy of water skin decontamination in vivo in humans: A systematic review. Journal of Applied Toxicology 42:3, pages 346-359.
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Chavy Chiang, Nadia Kashetsky, Aileen M. Feschuk, Anuk Burli, Rebecca M. Law & Howard I. Maibach. 2022. Dermal Absorption and Decontamination. Dermal Absorption and Decontamination 59 81 .
Chavy Chiang, Nadia Kashetsky, Aileen M. Feschuk, Anuk Burli, Rebecca M. Law & Howard I. Maibach. 2022. Dermal Absorption and Decontamination. Dermal Absorption and Decontamination 39 58 .
Aileen M. Feschuk, Nadia Kashetsky, Chavy Chiang, Anuk Burli, Halie Burdick & Howard I. Maibach. 2022. Dermal Absorption and Decontamination. Dermal Absorption and Decontamination 235 257 .
Nadia Kashetsky, Rebecca M. Law & Howard I. Maibach. 2022. Dermal Absorption and Decontamination. Dermal Absorption and Decontamination 1 24 .
Stefan Mandić-Rajčević, Federico Maria Rubino & Claudio Colosio. 2021. Exposure and Risk Assessment of Pesticide Use in Agriculture. Exposure and Risk Assessment of Pesticide Use in Agriculture 199 224 .
Anuk Burli, Rebecca M. Law, Jocelyn Rodriguez & Howard I. Maibach. (2020) Organic compounds percutaneous penetration in vivo in man: Relationship to mathematical predictive model. Regulatory Toxicology and Pharmacology 112, pages 104614.
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Xiaoying Hui & Howard I. Maibach. 2020. Skin Decontamination. Skin Decontamination 1 24 .
Anne J. Keurentjes & Howard I. Maibach. (2019) Percutaneous penetration of drugs applied in transdermal delivery systems: an in vivo based approach for evaluating computer generated penetration models. Regulatory Toxicology and Pharmacology 108, pages 104428.
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Fan Chen, Yi Ye, Bo Jin, Bo Yi, Qingtao Wei & Linchuan Liao. (2018) Homicidal Paraquat Poisoning. Journal of Forensic Sciences 64:3, pages 941-945.
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Ruojie Zhang, Wenhao Wu, Zipei Zhang, Yeonhwa Park, Lili He, Baoshan Xing & David Julian McClements. (2017) Effect of the Composition and Structure of Excipient Emulsion on the Bioaccessibility of Pesticide Residue in Agricultural Products. Journal of Agricultural and Food Chemistry 65:41, pages 9128-9138.
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Sabine-Karen Lammoglia, Marc C. Kennedy, Enrique Barriuso, Lionel Alletto, Eric Justes, Nicolas Munier-Jolain & Laure Mamy. (2017) Assessing human health risks from pesticide use in conventional and innovative cropping systems with the BROWSE model. Environment International 105, pages 66-78.
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Howard W. Levitin & Christopher A. Kahn. 2016. Koenig and Schultz's Disaster Medicine. Koenig and Schultz's Disaster Medicine 232 240 .
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